T9114 |
β-Caryophyllene
|
87-44-5
|
97.31%
|
|
β-Caryophyllene acts as an CB2 receptor agonist.
|
T1915 |
AM251
|
183232-66-8
|
97.88%
|
|
AM251 is a effective CB1 receptor antagonist (IC50/Ki: 8 /7.49 nM) that displays 306-fold selectivity over CB2 receptors; also effective GPR55 agonist (EC50: 39 ...
|
T2635 |
Org 27569
|
868273-06-7
|
98%
|
|
Org 27569, an allosteric modulator of cannabinoid CB1 receptor, can induce a CB1 receptor state that is characterized by decreased inverse agonist affinity and e...
|
T5996 |
CB1-IN-1
|
1429239-98-4
|
98%
|
|
CB1-IN-1 is a peripherally restricted CB1R antagonist, for CB1R and CB2R with Ki of 0.3 nM and 21 nM,respectively.
|
T7375 |
A-836339
|
959746-77-1
|
98%
|
|
A-836339 acts as a potent cannabinoid receptor full agonist which has a higher affinity for the peripheral CB2 receptor (Ki = 0.64 nM) over the central CB1 recep...
|
T28468 |
PSNCBAM-1
|
877202-74-9
|
98.18%
|
|
PSNCBAM-1 is a CB1 receptor negative allosteric modulator (EC50 = 0.1 μM) with hypophagic effects in vivo. PSNCBAM-1 can be used for obesity studies.
|
T2264 |
AM281
|
202463-68-1
|
98.6%
|
|
AM 281, a cannabinoid antagonist, reduces neurologic dysfunction and mortality rate after cecal ligation and puncture in rats.
|
T7316 |
LY2828360
|
1231220-79-3
|
98.61%
|
|
LY2828360 is a cannabinoid (CB) receptor 2 agonist (Ki = 40.3 nM). It selectively activates CB2 over CB1 in a GTPγS binding assay (EC50s = 20.1 and >100,000 nM, ...
|
T6755 |
AM1241
|
444912-48-5
|
98.72%
|
|
AM-1241 is a selective cannabinoid CB2 receptor agonist with Ki of 3.4 nM, exhibits 82-fold selectivity over CB1 receptor.
|
T2S0271 |
Voacamine
|
3371-85-5
|
98.73%
|
|
Voacamine is an indole alkaloid. Voacamine exhibits potent cannabinoid CB1 receptor antagonistic activity. Voacamine also inhibits P-glycoprotein (P-gp) action i...
|
T8975 |
PSB-SB-487
|
1399049-81-0
|
98.78%
|
|
PSB-SB-487 is antagonist of GPR55.
|
T4453 |
JD-5037
|
1392116-14-1
|
98.87%
|
|
JD-5037 is a novel, peripherally restricted CB1R antagonist with an IC50 of 1.5 nM.
|
T10696 |
CB2 modulator 1
|
666261-80-9
|
99.02%
|
|
CB2 modulator 1 is a potent CB2 modulator. It can be used for the research for immune disorders, osteoporosis, inflammation, renal ischemia.
|
T21380 |
Pravadoline
|
92623-83-1
|
99.20%
|
|
Pravadoline is a cannabinoid receptor agonist. Pravadoline inhibited the PGs synthesis in mouse brain and displayed antinociceptive activity in rodents subjected...
|
TP1901L1 |
Hemopressin (rat) acetate(568588-77-2 free base)
|
TP1901L1
|
99.37%
|
|
Hemopressin (rat) acetate is a nonapeptide derived from the α1-chain of hemoglobin, is originally isolated from rat brain homogenates. Hemopressin is orally acti...
|
T3530 |
Otenabant
|
686344-29-6
|
99.44%
|
|
Otenabant has been investigated for the treatment of Obesity.
|
T12307 |
OMDM-6
|
616884-67-4
|
99.49%
|
|
OMDM-6 is a dual agonist of TRPV1(EC50 = 75 nM) and CB1 (Ki = 3.2 μM). OMDM-6 inhibits anandamide cellular uptake with a Ki of 7.0 μM.
|
T0851 |
Pregnenolone
|
145-13-1
|
99.5%
|
|
Pregnenolone is an endogenous steroid hormone synthesized from cholesterol, used in the treatment of Alzheimer's disease.
|
T6417 |
BML-190
|
2854-32-2
|
99.51%
|
|
BML-190 is a specific CB2 receptor inverse agonist (Ki: 435 nM), with 50-fold selectivity over CB1 receptor.
|
T8571 |
ML-184
|
794572-10-4
|
99.53%
|
|
ML-184 is a potent synthetic agonist of GPR55 with EC50 of 0.26 µM.
|