T0851 |
Pregnenolone
|
145-13-1
|
98%
|
|
Pregnenolone is an endogenous steroid hormone synthesized from cholesterol, used in the treatment of Alzheimer's disease.
|
T6417 |
BML-190
|
2854-32-2
|
98%
|
|
BML-190 is a specific CB2 receptor inverse agonist (Ki: 435 nM), with 50-fold selectivity over CB1 receptor.
|
T67745 |
CB2R/FAAH modulator-2
|
2876918-68-0
|
98%
|
|
CB2R/FAAH modulator-2 (compound 26) is a dual modulator targeting at CB2R and FAAH. CB2R/FAAH modulator-2 acts as a CB2R agonist and FAAH inhibitor, the Ki value...
|
T8571 |
ML-184
|
794572-10-4
|
98%
|
|
ML-184 is a potent synthetic agonist of GPR55 with EC50 of 0.26 µM.
|
T3S0738 |
Yangonin
|
500-62-9
|
98%
|
|
1. Yangonin is a novel CB receptor ligand, it exhibits affinity for the human recombinant CB receptor. 2. Yangonin could be a valuable candidate for the interv...
|
T5996 |
CB1-IN-1
|
1429239-98-4
|
98%
|
|
CB1-IN-1 is a peripherally restricted CB1R antagonist, for CB1R and CB2R with Ki of 0.3 nM and 21 nM,respectively.
|
T36520 |
COR659
|
544450-68-2
|
98%
|
|
COR659 is a GABAB positive allosteric modulator (PAM) . COR659 suppresses alcohol and chocolate self-administration in rats[1].
COR659 apparently exerts its effe...
|
T16928 |
SR144528
|
192703-06-3
|
98%
|
|
SR144528 is an antagonist of the CB2 receptor (Ki = 0.6 nM) and inhibits microsomal ACAT activity (IC50 = 3.6 μM).
|
T4478 |
CID 16020046
|
834903-43-4
|
98%
|
|
CID16020046 is a selective GPR55 antagonist, inhibiting GPR55 constitutive activity with IC50 of 0.15 μM in yeast.
|
T3699 |
Bay 59-3074
|
406205-74-1
|
98%
|
|
Bay 59-3074 is a CB1/CB2 receptor partial agonist (Ki: 48.3/45.5 nM). In rat models of chronic neuropathic and inflammatory pain, it displays anti-hyperalgesic a...
|
T12306 |
OMDM-5
|
616884-66-3
|
98%
|
|
OMDM-5 is a selective anandamide cellular uptake (ACU)inhibitor(Ki of 4.8 μM).
|
T22114 |
NESS 0327
|
494844-07-4
|
98%
|
|
NESS 0327 is a high selectivity antagonist of the cannabinoid CB1 receptor. NESS 0327 is more than 60,000-fold selective for the CB1 receptor.
|
T3736 |
Olivetol
|
500-66-3
|
98%
|
|
Olivetol (5-pentylresorcinol, 5-pentyl-1,3-benzenediol) is an organic compound found in certain species of lichen; it is also a precursor in various syntheses of...
|
TC0019 |
Pregnenolone acetate
|
1778-02-5
|
98%
|
|
Pregnenolone acetate is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. It acts as a signaling-specific inhibi...
|
T33452 |
ML192
|
460331-61-7
|
98%
|
|
ML192 is a selective GPR55 ligand antagonist. ML192 is an inhibitor that inhibits β-arrestin transport, ERK1/2 phosphorylation, and PKCβII translocation.
|
T1796 |
Otenabant hydrochloride
|
686347-12-6
|
98%
|
|
Otenabant hydrochloride (CP-945598) is a competitive, high affinity, selective antagonist of the CB1 receptor (Ki: 0.7 nM).
|
T22103 |
ML-193
|
713121-80-3
|
98%
|
|
ML-193 is a potent and selective GPR55 antagonist( IC50 : 221 nM). It shows more than 27-fold selectivity for GPR55 over GPR35, CB1 and CB2, and can improve the ...
|
T21861 |
Drinabant
|
358970-97-5
|
98%
|
|
Drinabant is an orally active CB1 receptor antagonist. Drinabant inhibits the agonist-stimulated calcium signal with IC50 values of 25 nM and 10 nM for the hCB1-...
|
T4654 |
(±)-Ibipinabant
|
362519-49-1
|
98%
|
|
SLV319 has been used in trials studying the treatment of Obesity and Obesity and Type 2 Diabetes.
|
TN2268 |
Tetrahydromagnolol
|
20601-85-8
|
98%
|
|
Tetrahydromagnolol can activate cannabinoid (CB) receptors.
|