Cannabinoid Receptor

Cannabinoid receptors are of a class of cell membrane receptors in the G protein-coupled receptor superfamily. As is typical of G protein-coupled receptors, the cannabinoid receptors contain seven transmembrane spanning domains. Cannabinoid receptors are activated by three major groups of ligands: endocannabinoids, produced by the mammillary body;[citation needed] plant cannabinoids (such as cannabidiol, produced by the cannabis plant); and synthetic cannabinoids (such as HU-210). All of the endocannabinoids and phytocannabinoids (plant based cannabinoids) are lipophilic, such as fat soluble compounds.

Cat. No.	Product name	CAS No.	Purity
T0851	Pregnenolone	145-13-1	98%
T0851	Pregnenolone is an endogenous steroid hormone synthesized from cholesterol, used in the treatment of Alzheimer's disease.
T6417	BML-190	2854-32-2	98%
T6417	BML-190 is a specific CB2 receptor inverse agonist (Ki: 435 nM), with 50-fold selectivity over CB1 receptor.
T67745	CB2R/FAAH modulator-2	2876918-68-0	98%
T67745	CB2R/FAAH modulator-2 (compound 26) is a dual modulator targeting at CB2R and FAAH. CB2R/FAAH modulator-2 acts as a CB2R agonist and FAAH inhibitor, the Ki value...
T8571	ML-184	794572-10-4	98%
T8571	ML-184 is a potent synthetic agonist of GPR55 with EC50 of 0.26 µM.
T3S0738	Yangonin	500-62-9	98%
T3S0738	1. Yangonin is a novel CB receptor ligand, it exhibits affinity for the human recombinant CB receptor. 2. Yangonin could be a valuable candidate for the interv...
T5996	CB1-IN-1	1429239-98-4	98%
T5996	CB1-IN-1 is a peripherally restricted CB1R antagonist, for CB1R and CB2R with Ki of 0.3 nM and 21 nM,respectively.
T36520	COR659	544450-68-2	98%
T36520	COR659 is a GABAB positive allosteric modulator (PAM) . COR659 suppresses alcohol and chocolate self-administration in rats[1]. COR659 apparently exerts its effe...
T16928	SR144528	192703-06-3	98%
T16928	SR144528 is an antagonist of the CB2 receptor (Ki = 0.6 nM) and inhibits microsomal ACAT activity (IC50 = 3.6 μM).
T4478	CID 16020046	834903-43-4	98%
T4478	CID16020046 is a selective GPR55 antagonist, inhibiting GPR55 constitutive activity with IC50 of 0.15 μM in yeast.
T3699	Bay 59-3074	406205-74-1	98%
T3699	Bay 59-3074 is a CB1/CB2 receptor partial agonist (Ki: 48.3/45.5 nM). In rat models of chronic neuropathic and inflammatory pain, it displays anti-hyperalgesic a...
T12306	OMDM-5	616884-66-3	98%
T12306	OMDM-5 is a selective anandamide cellular uptake (ACU)inhibitor(Ki of 4.8 μM).
T22114	NESS 0327	494844-07-4	98%
T22114	NESS 0327 is a high selectivity antagonist of the cannabinoid CB1 receptor. NESS 0327 is more than 60,000-fold selective for the CB1 receptor.
T3736	Olivetol	500-66-3	98%
T3736	Olivetol (5-pentylresorcinol, 5-pentyl-1,3-benzenediol) is an organic compound found in certain species of lichen; it is also a precursor in various syntheses of...
TC0019	Pregnenolone acetate	1778-02-5	98%
TC0019	Pregnenolone acetate is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. It acts as a signaling-specific inhibi...
T33452	ML192	460331-61-7	98%
T33452	ML192 is a selective GPR55 ligand antagonist. ML192 is an inhibitor that inhibits β-arrestin transport, ERK1/2 phosphorylation, and PKCβII translocation.
T1796	Otenabant hydrochloride	686347-12-6	98%
T1796	Otenabant hydrochloride (CP-945598) is a competitive, high affinity, selective antagonist of the CB1 receptor (Ki: 0.7 nM).
T22103	ML-193	713121-80-3	98%
T22103	ML-193 is a potent and selective GPR55 antagonist( IC50 : 221 nM). It shows more than 27-fold selectivity for GPR55 over GPR35, CB1 and CB2, and can improve the ...
T21861	Drinabant	358970-97-5	98%
T21861	Drinabant is an orally active CB1 receptor antagonist. Drinabant inhibits the agonist-stimulated calcium signal with IC50 values of 25 nM and 10 nM for the hCB1-...
T4654	(±)-Ibipinabant	362519-49-1	98%
T4654	SLV319 has been used in trials studying the treatment of Obesity and Obesity and Type 2 Diabetes.
TN2268	Tetrahydromagnolol	20601-85-8	98%
TN2268	Tetrahydromagnolol can activate cannabinoid (CB) receptors.