T15303 |
FMK 9a
|
1955550-51-2
|
98.97%
|
|
FMK 9a is an irreversible inhibitor of ATG4B with IC50 values of 80 and 73 nM in the TR-FRET and cellular-based LRA assays.
|
TN1249 |
3-Epiursolic acid
|
989-30-0
|
98.81%
|
|
3-Epiursolic acid may have antiinflammatory activity, it shows inhibition on Cathepsins L (catL), the IC50 value of 6.5 μM, cathepsins L (catL) and B play an imp...
|
T27695 |
JTE-607
|
188791-09-5
|
98.72%
|
|
JTE-607 is a cytokine production inhibitor. JTE-607 induces apoptosis accompanied by an increase in p21waf1/cip1 in acute myelogenous leukemia cells.
|
T27730 |
KGP94
|
1131456-28-4
|
98.52%
|
|
KGP94 is an inhibitor of cysteine protease Cathepsin L(CTSL).
|
T21616 |
L-006235
|
294623-49-7
|
98.38%
|
|
L-006235 is a potent and reversible inhibitor of cathepsin K with IC50 of 0.25 nM.
|
T19384 |
Isovalerylcarnitine
|
31023-24-2
|
98.24%
|
|
Isovalerylcarnitine (3-methylbutyrylcarnitine) is a small molecule compound produced by the catabolism of L-leucine and the accumulation of isovaleric acid. Isov...
|
T20626 |
Esomeprazole
|
119141-88-7
|
98.20%
|
|
Esomeprazole is the S-isomer of omeprazole, inhibits the lysosomal cysteine protease legumain to prevent cancer metastasis. Esomeprazole is a proton pump inhibit...
|
T12909 |
SID 26681509
|
958772-66-2
|
98.16%
|
|
SID 26681509 is a selective, reversible and competitive human cathepsin L inhibitor (IC50 of 56 nM).
|
T60150 |
(1S,2R)-Alicapistat
|
2221010-57-5
|
98.05%
|
|
(1S,2R)-Alicapistat ((1S,2R)-ABT-957) is a highly efficient, orally active compound that selectively inhibits human calpains 1 and 2, with promising implications...
|
T6583 |
MG-101
|
110044-82-1
|
98%
|
|
MG-101 (Calpain inhibitor I) is a cell-permeable and potent inhibitor of cysteine proteases including calpains and lysosomal cathepsins.
|
T3088 |
N-Ethylmaleimide
|
128-53-0
|
98%
|
|
N-Ethylmaleimide (NEM) is a sulfhydryl reagent that is widely used in experimental biochemical studies.
|
T7451 |
2-Cyanopyrimidine
|
14080-23-0
|
98%
|
|
2-Cyanopyrimidine (m-Hydroxyphenylpropionic acid) is inhibitor of cathepsin K(IC50 : 170 nM)
|
TQ0116 |
LY 3000328
|
1373215-15-6
|
97.83%
|
|
LY 3000328 (Cathepsin S inhibitor) is a potent, highly selective Cathepsin S (Cat S) inhibitor (IC50s: 7.7 and 1.67 nM for hCat S and mCat S).
|
T21509 |
CA 074
|
134448-10-5
|
97.80%
|
|
CA 074 is a potent inhibitor of cathepsin B with a Ki value of 2 to 5 nM.CA 074 inhibits ischemic hippocampal neuronal death in primates and attenuates retinopat...
|
T1850 |
Balicatib
|
354813-19-7
|
97.78%
|
|
Balicatib (AAE581) is a potent and selective inhibitor of cathepsin K, used in trials studying the treatment of osteoporosis.
|
T3420 |
CA-074 methyl ester
|
147859-80-1
|
97.26%
|
|
CA-074 methyl ester (Cathepsin B Inhibitor IV) is a specific inhibitor of Cathepsin B with neuroprotective, anti-cancer, and anti-inflammatory effects.
|
T16089 |
MK-0674
|
887781-62-6
|
100%
|
|
MK-0674 is an orally available, selective and potent cathepsin K inhibitor (IC50: 0.4 nM) that inhibits Cat B, Cat F, Cat L, and Cat S. It can be used in metabol...
|
T0448 |
(S)-(+)-Ibuprofen
|
51146-56-6
|
100%
|
|
(S)-(+)-Ibuprofen (Dexibuprofen) , is a non-steroidal anti-inflammatory drug (NSAID), inhibiting cyclooxygenase (COX).
|
T2470 |
MDL-28170
|
88191-84-8
|
|
|
MDL-28170 (Calpain Inhibitor III) is a Cysteine protease.
|
T19503 |
Papain
|
9001-73-4
|
|
|
Papain is a cysteine protease of the peptidase C1 family. Papain is used in food, pharmaceutical, textile, and cosmetic industries.
|