EGFR

The epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is a transmembrane protein that is a receptor for members of the epidermal growth factor family (EGF family) of extracellular protein ligands.

Cat. No.	Product name	CAS No.	Purity
T3024	Avitinib	1557267-42-1	99.87%
T3024	Avitinib, also known as AC0010 or AC0010MA, is an orally available, irreversible, epidermal growth factor receptor (EGFR) mutant-selective inhibitor, with potent...
T0078	Lapatinib	231277-92-2	99.89%
T0078	Lapatinib is a dual inhibitor of Lapatinib is a dual ErbB2/EGFR (IC50: 9.2/10.8 nM) inhibitor
T21312	Afatinib	850140-72-6	99.9%
T21312	Afatinib is an irreversible inhibitor of EGFR family (EGFR-wt, EGFR-L858R, EGFR-L858R/T790M and HER2 with IC50s of 0.5 nM, 0.4 nM, 10 nM and 14 nM , respectively...
T2446	KI8751	228559-41-9	99.9%
T2446	KI8751 is a potent and selective inhibitor of VEGFR2 with IC50 of 0.9 nM.
T2491	AZ-5104	1421373-98-9	99.9%
T2491	AZ5104 is a potent EGFR inhibitor.
T19814	CP-380736	179688-29-0	99.91%
T19814	CP-380736 is an epidermal growth factor receptor (EGFR) inhibitor. EGFR is a tyrosine kinase that activates MAPK, JNK, and Akt pathways, and is an important medi...
T1144L	Lidocaine Hydrochloride hydrate	6108-05-0	99.91%
T1144L	Lidocaine Hydrochloride hydrate is an amide local anesthetic, has anti-inflammatory property.
T1431	Khellin	82-02-0	99.92%
T1431	Khellin is a vasodilator that also has bronchodilatory action.
T3621	Brigatinib	1197953-54-0	99.93%
T3621	Brigatinib is a highly potent and selective ALK inhibitor.
T2364	Tucatinib	937263-43-9	99.96%
T2364	Irbinitinib(ARRY-380; ONT-380) is a potent and selective HER2 inhibitor (IC50: 8 nM).
T4485	Lazertinib	1903008-80-9	99.96%
T4485	Lazertinib is an effective, highly mutant-selective and irreversible EGFR-TKI with IC50 values of 1.7 nM, 2 nM, 5 nM, 20.6 nM and 76 nM for Del19/T790M, L858R/T7...
T2303	(S)-Afatinib	439081-18-2	99.96%
T2303	Afatinib (BIBW 2992) is an irreversible EGFR family inhibitor with IC50s of 0.5/0.4/10/14/1 nM for EGFRwt, EGFR (L858R), EGFR (L858R/T790M), HER2, and HER4, resp...
T6196	PP1	172889-26-8	99.97%
T6196	PP1, a specific and effective Src inhibitor, is with IC50 for Lck/Fyn is 5 nM/ 6 nM, respectively.
T0373	Erlotinib	183321-74-6	99.98%
T0373	Erlotinib is an EGFR inhibitor (IC50: 2 nM). It is used for the treatment of non-small cell lung cancer.
T12594	Pyrotinib dimaleate	1397922-61-0	98%
T12594	Pyrotinib dimaleate is a potent and selective dual inhibitor of EGFR/HER2 (IC50 s of 13 and 38 nM, respectively).
T22974	Methyl 2,5-dihydroxycinnamate	63177-57-1	98%
T22974	EGF receptor-associated tyrosine kinases inhibitor
T11160	EGFR-IN-5	2225887-26-1	98%
T11160	EGFR-IN-5 is a selective inhibitor of EGFR. The IC50s for EGFR, EGFR(L858R), EGFR(L858R/T790M), and EGFR(L858R/T790M/C797S) are 10.4, 1.1, 34, 7.2 nM, respective...
T23127	PD-161570	192705-80-9	98%
T23127	FGFR inhibitor
TQ0092	Naquotinib	1448232-80-1	98%
TQ0092	Naquotinib (ASP8273) is an orally available, mutant-selective and irreversible EGFR inhibitor; (IC50s: 8-33 nM and 230 nM toward EGFR mutants and EGFR.
T15621	Rilematovir	1383450-81-4	98%
T15621	Rilematovir is an inhibitor of fusion protein with antiviral activity and low cytotoxicity. Rilematovir can be used in studies about respiratory syncytial virus ...