Home Tools
Log in
Cart

EGFR

The epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is a transmembrane protein that is a receptor for members of the epidermal growth factor family (EGF family) of extracellular protein ligands.
Cat. No. Product name CAS No. Purity Chemical Structure
T3024 Avitinib 1557267-42-1 99.87%
Avitinib, also known as AC0010 or AC0010MA, is an orally available, irreversible, epidermal growth factor receptor (EGFR) mutant-selective inhibitor, with potent...
T0078 Lapatinib 231277-92-2 99.89%
Lapatinib is a dual inhibitor of Lapatinib is a dual ErbB2/EGFR (IC50: 9.2/10.8 nM) inhibitor
T21312 Afatinib 850140-72-6 99.9%
Afatinib is an irreversible inhibitor of EGFR family (EGFR-wt, EGFR-L858R, EGFR-L858R/T790M and HER2 with IC50s of 0.5 nM, 0.4 nM, 10 nM and 14 nM , respectively...
T2446 KI8751 228559-41-9 99.9%
KI8751 is a potent and selective inhibitor of VEGFR2 with IC50 of 0.9 nM.
T2491 AZ-5104 1421373-98-9 99.9%
AZ5104 is a potent EGFR inhibitor.
T19814 CP-380736 179688-29-0 99.91%
CP-380736 is an epidermal growth factor receptor (EGFR) inhibitor. EGFR is a tyrosine kinase that activates MAPK, JNK, and Akt pathways, and is an important medi...
T1144L Lidocaine Hydrochloride hydrate 6108-05-0 99.91%
Lidocaine Hydrochloride hydrate is an amide local anesthetic, has anti-inflammatory property.
T1431 Khellin 82-02-0 99.92%
Khellin is a vasodilator that also has bronchodilatory action.
T3621 Brigatinib 1197953-54-0 99.93%
Brigatinib is a highly potent and selective ALK inhibitor.
T2364 Tucatinib 937263-43-9 99.96%
Irbinitinib(ARRY-380; ONT-380) is a potent and selective HER2 inhibitor (IC50: 8 nM).
T4485 Lazertinib 1903008-80-9 99.96%
Lazertinib is an effective, highly mutant-selective and irreversible EGFR-TKI with IC50 values of 1.7 nM, 2 nM, 5 nM, 20.6 nM and 76 nM for Del19/T790M, L858R/T7...
T2303 (S)-Afatinib 439081-18-2 99.96%
Afatinib (BIBW 2992) is an irreversible EGFR family inhibitor with IC50s of 0.5/0.4/10/14/1 nM for EGFRwt, EGFR (L858R), EGFR (L858R/T790M), HER2, and HER4, resp...
T6196 PP1 172889-26-8 99.97%
PP1, a specific and effective Src inhibitor, is with IC50 for Lck/Fyn is 5 nM/ 6 nM, respectively.
T0373 Erlotinib 183321-74-6 99.98%
Erlotinib is an EGFR inhibitor (IC50: 2 nM). It is used for the treatment of non-small cell lung cancer.
T12594 Pyrotinib dimaleate 1397922-61-0 98%
Pyrotinib dimaleate is a potent and selective dual inhibitor of EGFR/HER2 (IC50 s of 13 and 38 nM, respectively).
T22974 Methyl 2,5-dihydroxycinnamate 63177-57-1 98%
EGF receptor-associated tyrosine kinases inhibitor
T11160 EGFR-IN-5 2225887-26-1 98%
EGFR-IN-5 is a selective inhibitor of EGFR. The IC50s for EGFR, EGFR(L858R), EGFR(L858R/T790M), and EGFR(L858R/T790M/C797S) are 10.4, 1.1, 34, 7.2 nM, respective...
T23127 PD-161570 192705-80-9 98%
FGFR inhibitor
TQ0092 Naquotinib 1448232-80-1 98%
Naquotinib (ASP8273) is an orally available, mutant-selective and irreversible EGFR inhibitor; (IC50s: 8-33 nM and 230 nM toward EGFR mutants and EGFR.
T15621 Rilematovir 1383450-81-4 98%
Rilematovir is an inhibitor of fusion protein with antiviral activity and low cytotoxicity. Rilematovir can be used in studies about respiratory syncytial virus ...
Avitinib
T3024
Avitinib, also known as AC0010 or AC0010MA, is an orally available, irreversible, epidermal growth factor receptor (EGFR) mutant-selective inhibitor, with potent...
Lapatinib
T0078
Lapatinib is a dual inhibitor of Lapatinib is a dual ErbB2/EGFR (IC50: 9.2/10.8 nM) inhibitor
Afatinib
T21312
Afatinib is an irreversible inhibitor of EGFR family (EGFR-wt, EGFR-L858R, EGFR-L858R/T790M and HER2 with IC50s of 0.5 nM, 0.4 nM, 10 nM and 14 nM , respectively...
KI8751
T2446
KI8751 is a potent and selective inhibitor of VEGFR2 with IC50 of 0.9 nM.
AZ-5104
T2491
AZ5104 is a potent EGFR inhibitor.
CP-380736
T19814
CP-380736 is an epidermal growth factor receptor (EGFR) inhibitor. EGFR is a tyrosine kinase that activates MAPK, JNK, and Akt pathways, and is an important medi...
Lidocaine Hydrochloride hydrate
T1144L
Lidocaine Hydrochloride hydrate is an amide local anesthetic, has anti-inflammatory property.
Khellin
T1431
Khellin is a vasodilator that also has bronchodilatory action.
Brigatinib
T3621
Brigatinib is a highly potent and selective ALK inhibitor.
Tucatinib
T2364
Irbinitinib(ARRY-380; ONT-380) is a potent and selective HER2 inhibitor (IC50: 8 nM).
Lazertinib
T4485
Lazertinib is an effective, highly mutant-selective and irreversible EGFR-TKI with IC50 values of 1.7 nM, 2 nM, 5 nM, 20.6 nM and 76 nM for Del19/T790M, L858R/T7...
(S)-Afatinib
T2303
Afatinib (BIBW 2992) is an irreversible EGFR family inhibitor with IC50s of 0.5/0.4/10/14/1 nM for EGFRwt, EGFR (L858R), EGFR (L858R/T790M), HER2, and HER4, resp...
PP1
T6196
PP1, a specific and effective Src inhibitor, is with IC50 for Lck/Fyn is 5 nM/ 6 nM, respectively.
Erlotinib
T0373
Erlotinib is an EGFR inhibitor (IC50: 2 nM). It is used for the treatment of non-small cell lung cancer.
Pyrotinib dimaleate
T12594
Pyrotinib dimaleate is a potent and selective dual inhibitor of EGFR/HER2 (IC50 s of 13 and 38 nM, respectively).
Methyl 2,5-dihydroxycinnamate
T22974
EGF receptor-associated tyrosine kinases inhibitor
EGFR-IN-5
T11160
EGFR-IN-5 is a selective inhibitor of EGFR. The IC50s for EGFR, EGFR(L858R), EGFR(L858R/T790M), and EGFR(L858R/T790M/C797S) are 10.4, 1.1, 34, 7.2 nM, respective...
PD-161570
T23127
FGFR inhibitor
Naquotinib
TQ0092
Naquotinib (ASP8273) is an orally available, mutant-selective and irreversible EGFR inhibitor; (IC50s: 8-33 nM and 230 nM toward EGFR mutants and EGFR.
Rilematovir
T15621
Rilematovir is an inhibitor of fusion protein with antiviral activity and low cytotoxicity. Rilematovir can be used in studies about respiratory syncytial virus ...
1 2 3 4 5 6 7 8 9 10 11 12