T3024 |
Avitinib
|
1557267-42-1
|
99.87%
|
|
Avitinib, also known as AC0010 or AC0010MA, is an orally available, irreversible, epidermal growth factor receptor (EGFR) mutant-selective inhibitor, with potent...
|
T0078 |
Lapatinib
|
231277-92-2
|
99.89%
|
|
Lapatinib is a dual inhibitor of Lapatinib is a dual ErbB2/EGFR (IC50: 9.2/10.8 nM) inhibitor
|
T21312 |
Afatinib
|
850140-72-6
|
99.9%
|
|
Afatinib is an irreversible inhibitor of EGFR family (EGFR-wt, EGFR-L858R, EGFR-L858R/T790M and HER2 with IC50s of 0.5 nM, 0.4 nM, 10 nM and 14 nM , respectively...
|
T2446 |
KI8751
|
228559-41-9
|
99.9%
|
|
KI8751 is a potent and selective inhibitor of VEGFR2 with IC50 of 0.9 nM.
|
T2491 |
AZ-5104
|
1421373-98-9
|
99.9%
|
|
AZ5104 is a potent EGFR inhibitor.
|
T19814 |
CP-380736
|
179688-29-0
|
99.91%
|
|
CP-380736 is an epidermal growth factor receptor (EGFR) inhibitor. EGFR is a tyrosine kinase that activates MAPK, JNK, and Akt pathways, and is an important medi...
|
T1144L |
Lidocaine Hydrochloride hydrate
|
6108-05-0
|
99.91%
|
|
Lidocaine Hydrochloride hydrate is an amide local anesthetic, has anti-inflammatory property.
|
T1431 |
Khellin
|
82-02-0
|
99.92%
|
|
Khellin is a vasodilator that also has bronchodilatory action.
|
T3621 |
Brigatinib
|
1197953-54-0
|
99.93%
|
|
Brigatinib is a highly potent and selective ALK inhibitor.
|
T2364 |
Tucatinib
|
937263-43-9
|
99.96%
|
|
Irbinitinib(ARRY-380; ONT-380) is a potent and selective HER2 inhibitor (IC50: 8 nM).
|
T4485 |
Lazertinib
|
1903008-80-9
|
99.96%
|
|
Lazertinib is an effective, highly mutant-selective and irreversible EGFR-TKI with IC50 values of 1.7 nM, 2 nM, 5 nM, 20.6 nM and 76 nM for Del19/T790M, L858R/T7...
|
T2303 |
(S)-Afatinib
|
439081-18-2
|
99.96%
|
|
Afatinib (BIBW 2992) is an irreversible EGFR family inhibitor with IC50s of 0.5/0.4/10/14/1 nM for EGFRwt, EGFR (L858R), EGFR (L858R/T790M), HER2, and HER4, resp...
|
T6196 |
PP1
|
172889-26-8
|
99.97%
|
|
PP1, a specific and effective Src inhibitor, is with IC50 for Lck/Fyn is 5 nM/ 6 nM, respectively.
|
T0373 |
Erlotinib
|
183321-74-6
|
99.98%
|
|
Erlotinib is an EGFR inhibitor (IC50: 2 nM). It is used for the treatment of non-small cell lung cancer.
|
T12594 |
Pyrotinib dimaleate
|
1397922-61-0
|
98%
|
|
Pyrotinib dimaleate is a potent and selective dual inhibitor of EGFR/HER2 (IC50 s of 13 and 38 nM, respectively).
|
T22974 |
Methyl 2,5-dihydroxycinnamate
|
63177-57-1
|
98%
|
|
EGF receptor-associated tyrosine kinases inhibitor
|
T11160 |
EGFR-IN-5
|
2225887-26-1
|
98%
|
|
EGFR-IN-5 is a selective inhibitor of EGFR. The IC50s for EGFR, EGFR(L858R), EGFR(L858R/T790M), and EGFR(L858R/T790M/C797S) are 10.4, 1.1, 34, 7.2 nM, respective...
|
T23127 |
PD-161570
|
192705-80-9
|
98%
|
|
FGFR inhibitor
|
TQ0092 |
Naquotinib
|
1448232-80-1
|
98%
|
|
Naquotinib (ASP8273) is an orally available, mutant-selective and irreversible EGFR inhibitor; (IC50s: 8-33 nM and 230 nM toward EGFR mutants and EGFR.
|
T15621 |
Rilematovir
|
1383450-81-4
|
98%
|
|
Rilematovir is an inhibitor of fusion protein with antiviral activity and low cytotoxicity. Rilematovir can be used in studies about respiratory syncytial virus ...
|