Endogenous Metabolite

Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as sex, age, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No.	Product name	CAS No.	Purity
T8110	(+)-Longifolene	475-20-7	98%
T8110	(+)-Longifolene is a naturally occurring.
T7475	S-Adenosyl-L-methionine	29908-03-0	98%
T7475	S-Adenosyl-L-methionine is an intermediate metabolite of methionine,for treatment of primary biliary cirrhosis and major depressive disorder.
T13733	Hydroxyphenylacetylglycine	28116-23-6	98%
T13733	Hydroxyphenylacetylglycine is an endogenous human metabolite.
T10164	5,6-Dihydroxyindole	3131-52-0	98%
T10164	5,6-Dihydroxyindole is a melanin precursor and has a broad-spectrum antibacterial, antiviral, antifungal, antiparasitic activity. It has cytotoxic effects and is...
T37280	PE(18:1(9Z)/0:0)	89576-29-4	98%
T37280	PE(18:1(9Z)/0:0) is a naturally-occurring lysophospholipid and an analog of plasmalogen lysophosphatidylethanolamine. PE(18:1(9Z)/0:0) induces transient increase...
T7173	[Leu5]-Enkephalin	58822-25-6	98%
T7173	[Leu5]-Enkephalin is an endogenous neuropeptide involved in nociception and an agonist of δ-opioid and µ-opioid receptors (Kis = 4.0 and 3.4 nM, respectively)
T7711	Uridine triphosphate	63-39-8	98%
T7711	Uridine triphosphate increases proliferation of human cancerous pancreatic duct epithelial cells by activating P2Y2 receptor.
PDK0014	3-Methylxanthine	1076-22-8	98%
PDK0014	3-Methylxanthine, a xanthine derivative, is a cyclic guanosine monophosphate (GMP) inhibitor, with an IC50 of 920 μM on guinea-pig isolated trachealis muscle.3-M...
T20172L	Kyotorphin acetate	T20172L	98%
T20172L	Kyotorphin acetate is an endogenous peptide with analgesia activity and can be used as a biomarker of Alzheimer disease.
T19302	D(-)-2-Aminobutyric acid	2623-91-8	98%
T19302	D(-)-2-Aminobutyric acid is the substrate of D-amino acid oxidase.
T4940	3-Methylhistamine dihydrochloride	36475-47-5	98%
T4940	N tau-methylhistamine is one of the histamine metabolites. N tau-methylhistamine in plasma and urine is a good parameter for histamine release, and the determina...
T13499	3-Methyluridine	2140-69-4	98%
T13499	3-Methyluridine is a modified nucleoside of cellular RNA.
TQ0284	Hydroxyphenyllactic acid	306-23-0	98%
TQ0284	Hydroxyphenyllactic acid is an antifungal metabolite.
T38022	2,6-Dibromophenol	608-33-3	98%
T38022	2,6-Dibromophenol is extracted from the skin and muscle of flatfish.
T37709	2,2,2-Trichloroethanol	115-20-8	98%
T37709	2,2,2-Trichloroethanol, the active form of the sedative hypnotic drug chloral hydrate, is an agonist for the nonclassical K2P channels TREK-1 (KCNK2) and TRAAK (...
T11054	DL-Norvaline	760-78-1	98%
T11054	DL-Norvaline is a non-competitive inhibitor of arginase. Derivatives of L-norvaline.
T36788	2-Methylacetophenone	577-16-2	98%
T36788	2-Methylacetophenone is a human endogenous metabolite.
T37501	Ethoxyacetic acid	627-03-2	98%
T37501	Ethoxyacetic acid is an endogenous metabolite.
T37859	SY-640	168705-70-2	98%
T37859	SY-640 is an Acetamide derivative. SY-640 exhibits potent hepatoprotective effect. SY-640 reduces liver injury in mice induced by Propionibacterium acnes and Lip...
TN3748	D-Asparagine	2058-58-4	98%
TN3748	D-Asparagine is a source of nitrogen for yeast strains. D-Asparagine is a competitive inhibitor of L-Asparagine hydrolysis (Ki = 0.24 mM).