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Endogenous Metabolite

Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as sex, age, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T20654 Heparin 9005-49-6 98%
Heparin
Heparin (Adomiparin) is a mucopolysaccharide sulfate often used as an anticoagulant in clinical medicine.Heparin has shown partial anti-inflammatory activity in ...
T81973 KR-27425 98%
KR-27425
Compound 13, an AChE activator 1, is a non-pyridinium oxime that reactivates paraoxon-inhibited acetylcholinesterase (AChE) [1].
T8110 (+)-Longifolene 475-20-7 98%
(+)-Longifolene
(+)-Longifolene is a naturally occurring.
T9455 4-hydroxyestrone-4-methyl ether 58562-33-7 98%
4-hydroxyestrone-4-methyl ether
4-hydroxyestrone-4-methyl ether (4-Methoxy Estrone) is the methylation of 4-OHE1, which is catalyzed by COMT.
T10029 1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine 35418-59-8 98%
1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine
1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine is an endogenous metabolite that has been found in the aging mouse brain.
T10185 6-Phosphogluconic acid 921-62-0 98%
6-Phosphogluconic acid
6-Phosphogluconic acid is a potent and competitive phosphoglucose isomerase (PGI) inhibitor (Kis: 48 μM for glucose 6-phosphate and 42 μM for fructose 6-phosphat...
T21500 Sphingosine-1-phosphate 26993-30-6 98%
Sphingosine-1-phosphate
Sphingosine-1-phosphate (S1P) is an agonist for S1P1-5 receptors and a ligand for GPR3, GPR6, GPR12.Sphingosine-1-phosphate is an intracellular second messenger ...
T19443L N-Acetylhistamine acetate 98%
N-Acetylhistamine acetate
N-Acetylhistamine acetate is a histamine metabolite. It can be used as a potential biomarker of histidine metabolism for anaphylactoid reactions.
T37991 15-keto Prostaglandin F2α 35850-13-6 98%
15-keto Prostaglandin F2α
15-keto Prostaglandin F2α is a metabolite of Prostaglandin F2α that lowers intraocular pressure in rabbits.
T10020 1-Methyluric acid 708-79-2 98%
1-Methyluric acid
1-Methyluric acid (1-Methylurate) acts on the bladder mucosa and increases the levels of insulin, triglycerides, cholesterol, and blood glucose.
T40887 N1,N12-Diacetylspermine dihydrochloride 77928-71-3 98%
N1,N12-Diacetylspermine dihydrochloride
N1,N12-Diacetylspermine dihydrochloride (Diacetylspermine 2HCl) is a diacetylated derivative of Spermine. The occurrence of cancer is associated with the up-regu...
T73602 Phosphorylcholine 3616-04-4 98%
Phosphorylcholine
Phosphorylcholine is widely present in the biological world, which is a phospholipid present in the eukaryotic biofilm, and also in the symbiotic bacteria or pat...
T75525 UDP-rhamnose 1955-26-6 98%
UDP-rhamnose
UDP-rhamnose (UDP-L-rhamnose) is a sugar nucleotide widely found in plants and animals and is used in the synthesis of pectin in cell walls.UDP-rhamnose is recog...
T76121 Phosphoglucomutase 9001-81-4 98%
Phosphoglucomutase
Phosphoglucomutase, an enzyme critical in glycolysis and gluconeogenesis, facilitates the interconversion of glucose-1-phosphate and glucose-6-phosphate by trans...
T76125 Creatininase 9025-13-2 98%
Creatininase
Creatininase (CAH) is a homohexameric enzyme found in Pseudomonas putida, which can be used in the study of biosensors for creatinine assays and chronic renal fa...
T8282 (S)-(−)-Perillyl alcohol 18457-55-1 98%
(S)-(−)-Perillyl alcohol
(S)-(−)-Perillyl alcohol (Perillyl alcohol) , a monoterpene found in lavender, inhibits the farnesylation of Ras, upregulates the mannose-6-phosphate receptor an...
T36667 2'-Deoxyadenosine-5'-triphosphate 1927-31-7 98%
2'-Deoxyadenosine-5'-triphosphate
2'-Deoxyadenosine-5'-triphosphate (Deoxyadenosine 5-triphosphate) (dATP) is a naturally occurring small molecule nucleotide used in cells for DNA synthesis or re...
T5614 3-Oxopentanedioic acid 542-05-2 98%
3-Oxopentanedioic acid
3-Oxopentanedioic acid (1,3-Acetonedicarboxylic acid) is a simple carboxylic acid, which may be used as a building block in organic chemistry. It has been found ...
T13123 Tentoxin 28540-82-1 98%
Tentoxin
Tentoxin, a cyclic peptide produced by phytopathogenic fungi, inactivates the F1 motor in sensitive plants at nanomolar to micromolar concentrations, whereas hig...
T66935 1-Aminopropan-2-ol 78-96-6 98%
1-Aminopropan-2-ol
1-Aminopropan-2-ol is involved in the metabolism of threonine in Bacillus subtilis strains and can be used as a nitrogen source on fungal media.
Heparin
T20654
Heparin (Adomiparin) is a mucopolysaccharide sulfate often used as an anticoagulant in clinical medicine.Heparin has shown partial anti-inflammatory activity in ...
KR-27425
T81973
Compound 13, an AChE activator 1, is a non-pyridinium oxime that reactivates paraoxon-inhibited acetylcholinesterase (AChE) [1].
(+)-Longifolene
T8110
(+)-Longifolene is a naturally occurring.
4-hydroxyestrone-4-methyl ether
T9455
4-hydroxyestrone-4-methyl ether (4-Methoxy Estrone) is the methylation of 4-OHE1, which is catalyzed by COMT.
1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine
T10029
1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine is an endogenous metabolite that has been found in the aging mouse brain.
6-Phosphogluconic acid
T10185
6-Phosphogluconic acid is a potent and competitive phosphoglucose isomerase (PGI) inhibitor (Kis: 48 μM for glucose 6-phosphate and 42 μM for fructose 6-phosphat...
Sphingosine-1-phosphate
T21500
Sphingosine-1-phosphate (S1P) is an agonist for S1P1-5 receptors and a ligand for GPR3, GPR6, GPR12.Sphingosine-1-phosphate is an intracellular second messenger ...
N-Acetylhistamine acetate
T19443L
N-Acetylhistamine acetate is a histamine metabolite. It can be used as a potential biomarker of histidine metabolism for anaphylactoid reactions.
15-keto Prostaglandin F2α
T37991
15-keto Prostaglandin F2α is a metabolite of Prostaglandin F2α that lowers intraocular pressure in rabbits.
1-Methyluric acid
T10020
1-Methyluric acid (1-Methylurate) acts on the bladder mucosa and increases the levels of insulin, triglycerides, cholesterol, and blood glucose.
N1,N12-Diacetylspermine dihydrochloride
T40887
N1,N12-Diacetylspermine dihydrochloride (Diacetylspermine 2HCl) is a diacetylated derivative of Spermine. The occurrence of cancer is associated with the up-regu...
Phosphorylcholine
T73602
Phosphorylcholine is widely present in the biological world, which is a phospholipid present in the eukaryotic biofilm, and also in the symbiotic bacteria or pat...
UDP-rhamnose
T75525
UDP-rhamnose (UDP-L-rhamnose) is a sugar nucleotide widely found in plants and animals and is used in the synthesis of pectin in cell walls.UDP-rhamnose is recog...
Phosphoglucomutase
T76121
Phosphoglucomutase, an enzyme critical in glycolysis and gluconeogenesis, facilitates the interconversion of glucose-1-phosphate and glucose-6-phosphate by trans...
Creatininase
T76125
Creatininase (CAH) is a homohexameric enzyme found in Pseudomonas putida, which can be used in the study of biosensors for creatinine assays and chronic renal fa...
(S)-(−)-Perillyl alcohol
T8282
(S)-(−)-Perillyl alcohol (Perillyl alcohol) , a monoterpene found in lavender, inhibits the farnesylation of Ras, upregulates the mannose-6-phosphate receptor an...
2'-Deoxyadenosine-5'-triphosphate
T36667
2'-Deoxyadenosine-5'-triphosphate (Deoxyadenosine 5-triphosphate) (dATP) is a naturally occurring small molecule nucleotide used in cells for DNA synthesis or re...
3-Oxopentanedioic acid
T5614
3-Oxopentanedioic acid (1,3-Acetonedicarboxylic acid) is a simple carboxylic acid, which may be used as a building block in organic chemistry. It has been found ...
Tentoxin
T13123
Tentoxin, a cyclic peptide produced by phytopathogenic fungi, inactivates the F1 motor in sensitive plants at nanomolar to micromolar concentrations, whereas hig...
1-Aminopropan-2-ol
T66935
1-Aminopropan-2-ol is involved in the metabolism of threonine in Bacillus subtilis strains and can be used as a nitrogen source on fungal media.
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TargetMol