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GluR

Glutamate receptors are synaptic and non synaptic receptors located primarily on the membranes of neuronal and glial cells.Glutamate receptors are responsible for the glutamate-mediated postsynaptic excitation of neural cells, and are important for neural communication, memory formation, learning, and regulation.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T16402 Org-26576 1026791-61-6 99.94%
Org-26576
Org-26576 is a positive allosteric modulator of the AMPA receptor.
T8862 ML 254 1428630-86-7 99.94%
ML 254
ML254 competitively interacts with the MPEP allosteric binding site. ML254 is highly selective for mGlu5 versus other mGlu receptors, has a clean ancillary Ricer...
T6468 D-glutamine 5959-95-5 99.92%
D-glutamine
D-glutamine, an D type stereoisomer of glutamine, is one of the 20 amino acids which is encoded by the standard genetic code.
T23353 (E/Z)-SIB-1893 6266-99-5 99.92%
(E/Z)-SIB-1893
(E/Z)-SIB-1893 (SIB 1893) is the racemate of (E)-SIB-1893 and (Z)-SIB-1893. (E)-SIB-1893 is a selective, noncompetitive mGluR5 antagonist with anticonvulsant act...
T22954 LY 456236 hydrochloride 338736-46-2 99.89%
LY 456236 hydrochloride
LY 456236 hydrochloride (MPMQ hydrochloride) is an mGlu1 receptor antagonist with an ic50 value of 143 nM. LY456236 has selective, non-competitive and oral activ...
T3379 Decanoic Acid 334-48-5 99.87%
Decanoic Acid
Decanoic Acid (Caprynic acid) acts as a non-competitive AMPA receptor antagonist.
T22692 CPCCOEt 179067-99-3 99.87%
CPCCOEt
CPCCOEt is a low affinity, selective, non-competitive and reversible antagonist of mGluR1b
T6726 VU0361737 1161205-04-4 99.86%
VU0361737
VU0361737 (ML-128) is a specific positive allosteric modulator (PAM) of mGlu4 receptor.The EC50 of VU 0361737 is 240 nM for the human receptors. The EC50 of VU 0...
T27951 LY392098 211311-39-6 99.85%
LY392098
LY392098 (AMPA receptor modulator-3) is an allosteric modulator of AMPA receptor with EC50 of 4.4 μM and can be used in studies about mammalian nervous system.
T23440 TC-N 22A 1314140-00-5 99.84%
TC-N 22A
TC-N 22A is a strong, selective, oral active mGlu4 forward allosteric regulator (PAM) that can cross the blood-brain barrier. EC50 expression of TC-N 22A in BHK ...
T15369L Gamma-DGG acetate(6729-55-1 free base) 2935387-13-4 99.81%
gamma-DGG acetate(6729-55-1 free base)
gamma-DGG acetate(6729-55-1 free base) (γ-D-Glutamylglycine) is a competitive blocker of AMPA receptor.
T0333 Aniracetam 72432-10-1 99.8%
Aniracetam
Aniracetam (Ro 13-5057)(Ro 13-5057), a nootropic and neuroprotective drug, selectively modulates the AMPA receptor and nAChR.
T23509 VU 0285683 327056-22-4 99.8%
VU 0285683
VU 0285683 is a specific negative allosteric modulator of mGluR5 with a high affinity for the MPEP binding site. VU 0285683 shows anxiolytic-like activity.
TN7044 S-(4-Hydroxybenzyl)glutathione 129636-38-0 99.78%
S-(4-Hydroxybenzyl)glutathione
L-γ-Glutamyl-S-[(4-hydroxyphenyl)methyl] was isolated as the major principle responsible for the inhibition of the in vitro binding of kainic acid to brain gluta...
T2497 MPEP hydrochloride 219911-35-0 99.75%
MPEP hydrochloride
MPEP hydrochloride is an effective and highly specific non-competitive antagonist at the mGlu5 receptor subtype (IC50: 36 nM).
T13424 (1R,2S)-VU0155041 1263273-14-8 99.73%
(1R,2S)-VU0155041
(1R,2S)-VU0155041 is the cis regioisomer of VU0155041 and a partial agonist of mGluR4.
T10191L 7-Chlorokynurenic acid 18000-24-3 99.72%
7-Chlorokynurenic acid
7-Chlorokynurenic acid (7-chloro-4-hydroxy-2-carboxyquinoline) is an effecitve and selective antagonist of NMDA receptor with IC50 of 0.56 μM for the glycine B c...
T0426 Piracetam 7491-74-9 99.72%
Piracetam
Piracetam (UCB-6215), a cyclic derivative of the neurotransmitter gamma-aminobutyric acid (GABA), is used in therapy of the extensive cognitive disorders.
T6134 IEM 1754 2HBr 162831-31-4 99.72%
IEM 1754 2HBr
IEM 1754 2HBr (IEM 1754 dihydrobromide) is a selective AMPA/kainate receptor blockers for GluR1 and GluR3 with IC50 of 6 μM.
T60224 1H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)- 175340-21-3 99.69%
1H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)-
1H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)- is a low activity isomer of S 18986. S 18986 is a AMPA receptor positive modu...
Org-26576
T16402
Org-26576 is a positive allosteric modulator of the AMPA receptor.
ML 254
T8862
ML254 competitively interacts with the MPEP allosteric binding site. ML254 is highly selective for mGlu5 versus other mGlu receptors, has a clean ancillary Ricer...
D-glutamine
T6468
D-glutamine, an D type stereoisomer of glutamine, is one of the 20 amino acids which is encoded by the standard genetic code.
(E/Z)-SIB-1893
T23353
(E/Z)-SIB-1893 (SIB 1893) is the racemate of (E)-SIB-1893 and (Z)-SIB-1893. (E)-SIB-1893 is a selective, noncompetitive mGluR5 antagonist with anticonvulsant act...
LY 456236 hydrochloride
T22954
LY 456236 hydrochloride (MPMQ hydrochloride) is an mGlu1 receptor antagonist with an ic50 value of 143 nM. LY456236 has selective, non-competitive and oral activ...
Decanoic Acid
T3379
Decanoic Acid (Caprynic acid) acts as a non-competitive AMPA receptor antagonist.
CPCCOEt
T22692
CPCCOEt is a low affinity, selective, non-competitive and reversible antagonist of mGluR1b
VU0361737
T6726
VU0361737 (ML-128) is a specific positive allosteric modulator (PAM) of mGlu4 receptor.The EC50 of VU 0361737 is 240 nM for the human receptors. The EC50 of VU 0...
LY392098
T27951
LY392098 (AMPA receptor modulator-3) is an allosteric modulator of AMPA receptor with EC50 of 4.4 μM and can be used in studies about mammalian nervous system.
TC-N 22A
T23440
TC-N 22A is a strong, selective, oral active mGlu4 forward allosteric regulator (PAM) that can cross the blood-brain barrier. EC50 expression of TC-N 22A in BHK ...
gamma-DGG acetate(6729-55-1 free base)
T15369L
gamma-DGG acetate(6729-55-1 free base) (γ-D-Glutamylglycine) is a competitive blocker of AMPA receptor.
Aniracetam
T0333
Aniracetam (Ro 13-5057)(Ro 13-5057), a nootropic and neuroprotective drug, selectively modulates the AMPA receptor and nAChR.
VU 0285683
T23509
VU 0285683 is a specific negative allosteric modulator of mGluR5 with a high affinity for the MPEP binding site. VU 0285683 shows anxiolytic-like activity.
S-(4-Hydroxybenzyl)glutathione
TN7044
L-γ-Glutamyl-S-[(4-hydroxyphenyl)methyl] was isolated as the major principle responsible for the inhibition of the in vitro binding of kainic acid to brain gluta...
MPEP hydrochloride
T2497
MPEP hydrochloride is an effective and highly specific non-competitive antagonist at the mGlu5 receptor subtype (IC50: 36 nM).
(1R,2S)-VU0155041
T13424
(1R,2S)-VU0155041 is the cis regioisomer of VU0155041 and a partial agonist of mGluR4.
7-Chlorokynurenic acid
T10191L
7-Chlorokynurenic acid (7-chloro-4-hydroxy-2-carboxyquinoline) is an effecitve and selective antagonist of NMDA receptor with IC50 of 0.56 μM for the glycine B c...
Piracetam
T0426
Piracetam (UCB-6215), a cyclic derivative of the neurotransmitter gamma-aminobutyric acid (GABA), is used in therapy of the extensive cognitive disorders.
IEM 1754 2HBr
T6134
IEM 1754 2HBr (IEM 1754 dihydrobromide) is a selective AMPA/kainate receptor blockers for GluR1 and GluR3 with IC50 of 6 μM.
1H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)-
T60224
1H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)- is a low activity isomer of S 18986. S 18986 is a AMPA receptor positive modu...
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TargetMol