T16402 |
Org-26576
|
1026791-61-6
|
99.94%
|
|
Org-26576 is a positive allosteric modulator of the AMPA receptor.
|
T8862 |
ML 254
|
1428630-86-7
|
99.94%
|
|
ML254 competitively interacts with the MPEP allosteric binding site. ML254 is highly selective for mGlu5 versus other mGlu receptors, has a clean ancillary Ricer...
|
T6468 |
D-glutamine
|
5959-95-5
|
99.92%
|
|
D-glutamine, an D type stereoisomer of glutamine, is one of the 20 amino acids which is encoded by the standard genetic code.
|
T23353 |
(E/Z)-SIB-1893
|
6266-99-5
|
99.92%
|
|
(E/Z)-SIB-1893 (SIB 1893) is the racemate of (E)-SIB-1893 and (Z)-SIB-1893. (E)-SIB-1893 is a selective, noncompetitive mGluR5 antagonist with anticonvulsant act...
|
T22954 |
LY 456236 hydrochloride
|
338736-46-2
|
99.89%
|
|
LY 456236 hydrochloride (MPMQ hydrochloride) is an mGlu1 receptor antagonist with an ic50 value of 143 nM. LY456236 has selective, non-competitive and oral activ...
|
T3379 |
Decanoic Acid
|
334-48-5
|
99.87%
|
|
Decanoic Acid (Caprynic acid) acts as a non-competitive AMPA receptor antagonist.
|
T22692 |
CPCCOEt
|
179067-99-3
|
99.87%
|
|
CPCCOEt is a low affinity, selective, non-competitive and reversible antagonist of mGluR1b
|
T6726 |
VU0361737
|
1161205-04-4
|
99.86%
|
|
VU0361737 (ML-128) is a specific positive allosteric modulator (PAM) of mGlu4 receptor.The EC50 of VU 0361737 is 240 nM for the human receptors. The EC50 of VU 0...
|
T27951 |
LY392098
|
211311-39-6
|
99.85%
|
|
LY392098 (AMPA receptor modulator-3) is an allosteric modulator of AMPA receptor with EC50 of 4.4 μM and can be used in studies about mammalian nervous system.
|
T23440 |
TC-N 22A
|
1314140-00-5
|
99.84%
|
|
TC-N 22A is a strong, selective, oral active mGlu4 forward allosteric regulator (PAM) that can cross the blood-brain barrier. EC50 expression of TC-N 22A in BHK ...
|
T15369L |
Gamma-DGG acetate(6729-55-1 free base)
|
2935387-13-4
|
99.81%
|
|
gamma-DGG acetate(6729-55-1 free base) (γ-D-Glutamylglycine) is a competitive blocker of AMPA receptor.
|
T0333 |
Aniracetam
|
72432-10-1
|
99.8%
|
|
Aniracetam (Ro 13-5057)(Ro 13-5057), a nootropic and neuroprotective drug, selectively modulates the AMPA receptor and nAChR.
|
T23509 |
VU 0285683
|
327056-22-4
|
99.8%
|
|
VU 0285683 is a specific negative allosteric modulator of mGluR5 with a high affinity for the MPEP binding site. VU 0285683 shows anxiolytic-like activity.
|
TN7044 |
S-(4-Hydroxybenzyl)glutathione
|
129636-38-0
|
99.78%
|
|
L-γ-Glutamyl-S-[(4-hydroxyphenyl)methyl] was isolated as the major principle responsible for the inhibition of the in vitro binding of kainic acid to brain gluta...
|
T2497 |
MPEP hydrochloride
|
219911-35-0
|
99.75%
|
|
MPEP hydrochloride is an effective and highly specific non-competitive antagonist at the mGlu5 receptor subtype (IC50: 36 nM).
|
T13424 |
(1R,2S)-VU0155041
|
1263273-14-8
|
99.73%
|
|
(1R,2S)-VU0155041 is the cis regioisomer of VU0155041 and a partial agonist of mGluR4.
|
T10191L |
7-Chlorokynurenic acid
|
18000-24-3
|
99.72%
|
|
7-Chlorokynurenic acid (7-chloro-4-hydroxy-2-carboxyquinoline) is an effecitve and selective antagonist of NMDA receptor with IC50 of 0.56 μM for the glycine B c...
|
T0426 |
Piracetam
|
7491-74-9
|
99.72%
|
|
Piracetam (UCB-6215), a cyclic derivative of the neurotransmitter gamma-aminobutyric acid (GABA), is used in therapy of the extensive cognitive disorders.
|
T6134 |
IEM 1754 2HBr
|
162831-31-4
|
99.72%
|
|
IEM 1754 2HBr (IEM 1754 dihydrobromide) is a selective AMPA/kainate receptor blockers for GluR1 and GluR3 with IC50 of 6 μM.
|
T60224 |
1H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)-
|
175340-21-3
|
99.69%
|
|
1H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)- is a low activity isomer of S 18986. S 18986 is a AMPA receptor positive modu...
|