GluR

Glutamate receptors are synaptic and non synaptic receptors located primarily on the membranes of neuronal and glial cells.Glutamate receptors are responsible for the glutamate-mediated postsynaptic excitation of neural cells, and are important for neural communication, memory formation, learning, and regulation.

Cat. No.	Product name	CAS No.	Purity
T60224	1H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)-	175340-21-3	99.69%
T60224	1H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)- is a low activity isomer of S 18986. S 18986 is a AMPA receptor positive modu...
T65135	Kynurenic acid	492-27-3	99.69%
T65135	Kynurenic acid (Quinurenic acid) is an endogenous tryptophan active metabolite, a triple antagonist of NMDA, glutamate, α7 nicotinic acetylcholine receptor, and ...
T6727	VU0364770	61350-00-3	99.66%
T6727	VU0364770 (VU 0364770)(EC50=1.1 μM), a positive allosteric modulator(PAM) of mGlu4, shows insignificant activity at 68 other receptors, including other mGlu subt...
T22638	CBiPES hydrochloride	856702-40-4	99.66%
T22638	CBiPES hydrochloride (CBiPES HCl) is a potent orthosteric modulator of the mGlu2 receptor with an EC50 value of 92.8 nM.CBiPES hydrochloride blocks the action of...
T0024	Primidone	125-33-7	99.66%
T0024	Primidone (NCI-C56360) is a potent anticonvulsant agent. It is a neuronal voltage-gated sodium channel blocker and has value in the study of epilepsy, essential ...
T29126	VU0360172	1310012-12-4	99.65%
T29126	VU0360172 is a positive allosteric modulator of mGlu5 receptors (EC50 = 16 nM; Ki = 195 nM).
T23215L	(R)-3,4-DCPG HCl	T23215L	99.64%
T23215L	(R)-3,4-DCPG HCl is a potent and selective mGlu8a receptor agonist that activates metabotropic glutamate receptors on primary afferent terminals in the neonatal ...
T0051	Urethane	51-79-6	99.63%
T0051	Urethane (Ethylurethane) was an antineoplastic agent .Now is used for other medicinal purposes.
T37734	AMPA receptor modulator-2	2034181-36-5	99.62%
T37734	AMPA receptor modulator-2 (Example 134) is a AMPA receptor modulator, with a pIC50 of 10.1 for TARPγ2 dependent AMPA receptor[1]. pIC50 = -lgIC50. [1]. BERRY CYN...
T10881	CPPHA	693288-97-0	99.61%
T10881	CPPHA, a positive allosteric modulator of glutamate receptors mGluR5 and mGluR1, is commonly used in development for central nervous system diseases.
TQ0094	JNJ-40411813	1127498-03-6	99.57%
TQ0094	JNJ-40411813 (ADX-71149) (ADX-71149) is a new positive allosteric modulator of the metabotropic glutamate 2 receptor (mGlu2R, EC50: 147 nM).
T21995	XAP044	196928-50-4	99.56%
T21995	XAP044 is a mGlu7-selective antagonist which inhibits lateral amygdala long term potentiation (LTP) in brain slices from wild type mice with a half-maximal block...
T5509	FPTQ	864863-72-9	99.56%
T5509	FPTQ is a highly effective antagonist of mGluR 1, displaying IC50 values of 6 nM and 1.4 nM for human and mouse mGluR1 respectively [1]. In addition to its robus...
T11032	DHPG	146255-66-5	99.55%
T11032	DHPG ((RS)-3,5-DHPG) ((RS)-3,5-DHPG) is an effective antagonist of mGluR linked to phospholipase D. It is an amino acid that can be used as a selective and poten...
T11393	GET73	202402-01-5	99.54%
T11393	GET73 (Gamma hydroxybutyric acid analogue) is an negative allosteric modulator of mGluR5. GET73 is a naturally occurring neurotransmitter. GET73 has anti-alcohol...
T3484	Trans-ACPD	67684-64-4	99.53%
T3484	trans-ACPD ((±)-trans-ACPD) is an equimolecular mixture of (1S, 3R)- and (1R, 3S)-ACPD. trans-ACPD is a selective agonist of the mGluR (metabotropic glutamate re...
T10573	BMT-145027	2018282-44-3	99.5%
T10573	BMT-145027 is a positive allosteric modulator of mGluR5 without inherent agonist activity (EC50 = 47 nM).
T10432L	AZD-8529 mesylate	1314217-69-0	99.5%
T10432L	AZD-8529 mesylate is a highly selective, and orally bioavailable positive allosteric modulator of mGluR2 (EC50: 285 nM). It shows no positive allosteric modulato...
T8626	Transtorine	13593-94-7	99.49%
T8626	Transtorine (1,4-DIHYDRO-4-OXOQUINOLINE-2-CARBOXYLIC ACID) is a GluR and NMDA inhibitor.
T8779	HBT1	489408-02-8	99.48%
T8779	HBT1 is an AMPA receptor potentiator that induces production of brain-derived neurotrophic factor (BDNF) and exhibits little agonistic effect in primary neurons....