GluR

Glutamate receptors are synaptic and non synaptic receptors located primarily on the membranes of neuronal and glial cells.Glutamate receptors are responsible for the glutamate-mediated postsynaptic excitation of neural cells, and are important for neural communication, memory formation, learning, and regulation.

Cat. No.	Product name	CAS No.	Purity
T5083	L-Cysteic acid monohydrate	23537-25-9	99.28%
T5083	L-Cysteic acid monohydrate (3-Sulfo-L-alanine Monohydrate) is an oxidation product of L-cysteine that may be used as a competitive inhibitor of the bacterial asp...
T23008L	MMPIP hydrochloride	1215566-78-1	99.26%
T23008L	MMPIP hydrochloride is a selective antagonist of allosteric mGluR7. MMPIP hydrochloride can be used in research on the roles of mGluR7 on central nervous system ...
T16816	S 18986	175340-20-2	99.25%
T16816	S 18986 is a selective, orally active, brain penetrant positive allosteric modulator of AMPA-type receptors, showcasing cognitive-enhancing properties in rodents...
T8457	NPS2390	226878-01-9	99.24%
T8457	NPS2390 is a first generation quinoxaline derivative that acts as a noncompetitive antagonist of mGluR1 and mGluR5 (IC50 of 5.2 and 82 nM, respectively)
T23514	VU-1545	890764-63-3	99.24%
T23514	VU-1545 is mGlu5 positive allosteric modulator.
T12012	Methoxy-PEPy	524924-76-3	99.20%
T12012	Methoxy-PEPy is a potent and selective mGlu5 receptor inhibitor with an IC50 value of 1 nM.
T23291	(S)-3-Hydroxyphenylglycine	71301-82-1	99.18%
T23291	(S)-3-Hydroxyphenylglycine is an agonist of group I metabotropic glutamate receptors (mGluRs).
T2053	ADX-47273	851881-60-2	99.18%
T2053	ADX-47273 (BA 94673139) is a positive and selective allosteric modulator for the metabotropic glutamate receptor subtype mGluR5(EC50=170 nM).
T3451	JNJ-42153605	1254977-87-1	99.13%
T3451	JNJ-42153605 is a mGlu2 receptor positive allosteric modulator (EC50: 17 nM).
T23000	ML289	1382481-79-9	99.09%
T23000	ML289 (VU0463597) is a potent, selective, and CNS-penetrant negative allosteric modulator of mGlu3 (IC50=0.66 μM), demonstrating over 15-fold selectivity compare...
T23003	ML337	1443118-44-2	99.09%
T23003	ML337 is a negative allosteric modulator of mGlu3 with an IC50 of 593 nM.
T23288L	(S)-3,4-DCPG HCl	T23288L	99.06%
T23288L	(S)-3,4-DCPG HCl ((S)-3,4-Dicarboxyphenylglycine HCl) is a selective metabotropic glutamate receptor 8a (mGluR8a) agonist that has an effect on human mGluR8-expr...
T3486	3-MATIDA	518357-51-2	99.05%
T3486	3-MATIDA is an effective mGluR-1 antagonist (IC50: 6.3 μM, rat mGluR-1a). Displays ≥ 40-fold selectivity over other receptors: mGluR-5, mGluR-2, mGluR-4 (mGluR-4...
T61972	Pomaglumetad methionil hydrochloride	635318-26-2	99.01%
T61972	Pomaglumetad methionine hydrochloride (LY2140023 hydrochloride) is a methionine prodrug of LY404039 with oral activity. LY404039 is a selective mGlu2/3 receptor ...
T9970	MGluR3 modulator-1	374548-18-2	98.99%
T9970	mGluR3 modulator-1 (1-ethyl-3-(morpholin-4-yl)-5,6,7,8-tetrahydroisoquinoline-4-carbonitrile) is a positive allosteric modulator of mGluR3 and can be used in stu...
T13318	VU0650786	1809085-30-0	98.96%
T13318	VU0650786 is a selective and potent CNS penetrant negative allosteric modulator of metabotropic glutamate receptor subtype 3 (mGlu3 NAM) (IC50: 392 nM), with ant...
T13323	VU6012962	2313526-86-0	98.95%
T13323	VU6012962 is an orally bioavailable negative allosteric modulator of CNS-penetrant metabotropic glutamate receptor 7(mGlu7; IC50: 347 nM).
T0313	Evans blue	314-13-6	98.85%
T0313	Evans blue (C.I. 23860) is an azo dye, inhibits L-glutamate uptake via the membrane-bound excitatory amino acid transporter (EAAT).
T31208	Dasolampanel	503294-13-1	98.81%
T31208	Dasolampanel (NGX-426) is an orally available ionotropic glutamate receptor AMPA and Kainate receptor antagonist for the study of chronic pain disorders, includi...
T4573	Cyclothiazide	2259-96-3	98.74%
T4573	Cyclothiazide is a benzothiadiazide that acts as a potentiator of AMPA receptorsthat potently inhibits AMPA receptor desensitization, positively modulating its r...