T22976 |
MFZ 10-7
|
1224431-15-5
|
98%
|
|
MFZ 10-7 is anegative allosteric modulator of the mGluR5.
|
T23259 |
(RS)-3-Hydroxyphenylglycine
|
31932-87-3
|
98%
|
|
PI-linked metabotropic glutamate receptors agonist
|
T29135 |
VU0422288
|
1630936-95-6
|
98%
|
|
VU0422288 (ML396) is a potent orthosteric modulator of type III mGlu receptors (mGlus).VU0422288 shows inhibition of mGluR4, mGluR7, and mGluR8 in a calcium mobi...
|
T23303 |
S-Sulfo-L-cysteine sodium salt
|
7381-67-1
|
98%
|
|
S-Sulfo-L-cysteine sodium salt shows a weak affinity for mGluR1α and mGluR5a at high concentrations and has potential antioxidant activity.
|
T13321 |
VU6005649
|
2137047-43-7
|
98%
|
|
VU6005649 is an agonist of CNS penetrant mGlu7/8 receptor (EC50s: 0.65 μM and 2.6 μM for mGlu7 receptor and mGlu8 receptor, respectively).
|
T41301 |
L-Cysteinesulfinic acid monohydrate
|
207121-48-0
|
98%
|
|
L-Cysteinesulfinic acid monohydrate is a potent agonist at rat metabotropic glutamate receptors (mGluRs) with pEC50s of 3.92, 4.6, 3.9, 2.7, 4.0, and 3.94 for mG...
|
T15456 |
GYKI 53655 hydrochloride
|
143692-48-2
|
98%
|
|
GYKI 53655 hydrochloride (LY300168 hydrochloride) is an antagonist of AMPA and is used in the study of neurological disorders.
|
T3473 |
(S)-ATPO
|
252930-37-3
|
98%
|
|
(S)-ATPO is Competitive antagonist at GluR1-4 (AMPA-preferring) receptors.
|
T22711 |
DCB
|
6971-97-7
|
98%
|
|
DCB (3,3'-dichlorobenzaldazine) is an allosteric ligand for mGluR5 and shows the negative modulatory effect of 3,3′-dimethoxybenzaldazine (DMeOB). DCB blocks the...
|
T3479 |
(RS)-MCPG
|
146669-29-6
|
98%
|
|
(RS)-MCPG ((±)-MCPG) is a non-selective group I/II metabotropic glutamate receptor antagonist.
|
T1443 |
Memantine hydrochloride
|
41100-52-1
|
98%
|
|
Memantine hydrochloride (Memantine HCl) is an AMANTADINE derivative that has some dopaminergic effects. Memantine hydrochloride has been proposed as an antiparki...
|
T22840 |
HexylHIBO
|
334887-43-3
|
98%
|
|
HexylHIBO is a type I mGluR antagonist that inhibits mGlu1a and mGlu5a, with Kb values of 140 and 110 μM, respectively.HexylHIBO decreases sEPSC in rats.
|
T9133 |
Caroverine hydrochloride
|
55750-05-5
|
98%
|
|
Caroverine hydrochloride (Caroverine HCL) is a potent, competitive and reversible antagonist of NMDA and AMPA glutamate receptor. It is also an antioxidant and c...
|
T22638 |
CBiPES hydrochloride
|
856702-40-4
|
98%
|
|
CBiPES hydrochloride (CBiPES HCl) is a potent orthosteric modulator of the mGlu2 receptor with an EC50 value of 92.8 nM.CBiPES hydrochloride blocks the action of...
|
T6562 |
Latrepirdine dihydrochloride
|
97657-92-6
|
98%
|
|
Latrepirdine dihydrochloride (Dimebolin dihydrochloride) is an orally active, and neuroactive antagonist of multiple drug targets, including histamine receptors,...
|
T13323 |
VU6012962
|
2313526-86-0
|
98%
|
|
VU6012962 is an orally bioavailable negative allosteric modulator of CNS-penetrant metabotropic glutamate receptor 7(mGlu7; IC50: 347 nM).
|
T20571 |
Cis-PDA
|
46026-75-9
|
98%
|
|
cis-PDA (cis PDA) is a general ionotropic receptor antagonist. cis-PDA acts by blocking NMDA, AMPA, and kainate-mediated responses.
|
T20191 |
(-)-Camphoric acid
|
560-09-8
|
98%
|
|
(-)-Camphoric acid (L-Camphoric acid) is a less active enantiomer of Camphoric acid which induces GluR expression.
|
T9011 |
VU0155094
|
731006-86-3
|
98%
|
|
VU0155094 (ML 397) is a positive allosteric modulator with differential activity at the various group III mGluRs.
|
T15819 |
LY377604
|
204592-94-9
|
98%
|
|
LY377604 is a human β3-adrenergic receptor agonist (EC50: 2.4 nM). It also a β1- and β2-adrenergic receptor antagonist.
|