HIV Protease

HIV-1 protease (PR) is a retroviral aspartyl protease (retropepsin), an enzyme involved with peptide bond hydrolysis in retroviruses, that is essential for the life-cycle of HIV, the retrovirus that causes AIDS. HIV protease cleaves newly synthesized polyproteins (namely, Gag and Gag-Pol[3]) at nine cleavage sites to create the mature protein components of an HIV virion, the infectious form of a virus outside of the host cell. Without effective HIV protease, HIV virions remain uninfectious.

Cat. No.	Product name	CAS No.	Purity
T10111	3-Deazaadenosine hydrochloride	86583-19-9	99.99%
T10111	3-Deazaadenosine hydrochloride is an inhibitor of S-adenosylhomocysteine hydrolase (Ki: 3.9 µM). It has anti-inflammatory, anti-proliferative, and anti-HIV activ...
T4493	Bictegravir	1611493-60-7	99.98%
T4493	Bictegravir (GS-9883) is a potent inhibitor of HIV-1 integrase (IC50: 7.5 nM).
T8689	Chloroquine	54-05-7	99.98%
T8689	Chloroquine is a Toll-like receptor inhibitor that inhibits autophagy. Chloroquine has anti-malarial and anti-inflammatory activity and is widely used in the tre...
T0828	Bromhexine hydrochloride	611-75-6	99.98%
T0828	Bromhexine hydrochloride (Bisolvon) is a mucolytic agent used in the treatment of respiratory disorders associated with viscid or excessive mucus.
T3122	Fangchinoline	436-77-1	99.98%
T3122	Fangchinoline (Tetrandrine B) is extracted from Stephania tetrandra S. Moore.
T3172	Trovirdine	149488-17-5	99.97%
T3172	Trovirdine (LY300046) is a thiourea non-nucleoside reverse transcriptase inhibitor.
T3730	Methyl gallate	99-24-1	99.96%
T3730	Methyl gallate (Gallincin) is a reverse transcriptase inhibitor with antioxidant, anti-HIV-1 and HIV-1 enzyme inhibition activities.
T4962	Zingibroside R1	80930-74-1	99.96%
T4962	Zingibroside R1 (Ginsenoside Z-R1) has anti-HIV-1 activity.
T4S1718	Punicalin	65995-64-4	99.95%
T4S1718	Punicalin exerts anti-inflammatory, antioxidative, and anti-hepatotoxic activities, it shows inhibitory activity on HIV-1 reverse transcriptase in a dose-depende...
T41249	Tenofovir alafenamide fumarate	379270-38-9	99.95%
T41249	Tenofovir alafenamide fumarate (GS-7340 fumarate) is an orally available Tenofovir precursor compound Tenofovir alafenamide fumarate has anti-HIV activity and ca...
T4537	Cholic acid sodium	361-09-1	99.95%
T4537	Cholic acid sodium (SodiumCholate) exhibits a strong spermicidal and antiviral [anti-human immunodeficiency virus (HIV)-1] activity.
T10570	Fostemsavir Tris	864953-39-9	99.95%
T10570	Fostemsavir Tris (BMS-663068 Tris) is the prodrug of BMS-626529,is a oral, safe and effective inhibitor of HIV-1 attachment. It inhibits human immunodeficiency v...
T0457	Probenecid	57-66-9	99.95%
T0457	Probenecid (Benemid) is a benzoic acid derivative with antihyperuricemic property.
TN1059	Ganoderic acid B	81907-61-1	99.95%
TN1059	Ganoderic acid B is a chemical marker in quality control of G. lucidum and related products. Ganoderic acid B-containing herbs has potential influence towards th...
T1267	Abacavir	136470-78-5	99.94%
T1267	Abacavir (Ziagen) is a nucleoside reverse transcriptase inhibitor analog of guanosine. This agent decreases HIV viral loads, retards or prevents the damage to th...
T31860	Fosdevirine	1018450-26-4	99.94%
T31860	Fosdevirine (GSK2248761) is a selective and potent non-nucleoside reverse transcriptase (NNRTI) inhibitor with anti-HIV activity for the study of neurological re...
T0289	9-Aminoacridine	90-45-9	99.93%
T0289	9-Aminoacridine is a highly fluorescent anti-infective dye used clinically as a topical antiseptic and experimentally as a mutagen, due to its interaction with D...
T6214	Emtricitabine	143491-57-0	99.93%
T6214	Emtricitabine (FTC) (FTC), a nucleoside reverse transcriptase inhibitor, exhibits inhibition activity against human immunodeficiency virus (HIV) and hepatitis B ...
T0710	L-Cycloserine	339-72-0	99.92%
T0710	L-Cycloserine ((-)-Cycloserine) irreversibly inhibits GABA pyridoxal 5′-phosphate-dependent aminotransferase in E. coli, as well in the brains of various animals...
T6846	Vesatolimod	1228585-88-3	99.92%
T6846	Vesatolimod (GS-9620) is an effective and specific orally active agonist of Toll-like receptor 7.