T7010 |
VER-155008
|
1134156-31-2
|
98%
|
|
VER-155008 is a potent Hsp70 family inhibitor with IC50 of 0.5 μM, 2.6 μM, and 2.6 μM in cell-free assays for HSP70, HSC70, and GRP78, respectively, >100-fold se...
|
T8829 |
2',4'-DIHYDROXYCHALCONE
|
1776-30-3
|
98%
|
|
2',4'-Dihydroxychalcone as a compound with Hsp90 inhibitory and antifungal effects
|
T9996 |
NCT-58
|
2411429-33-7
|
98%
|
|
NCT-58 is a potent C-terminal HSP90 inhibitor. NCT-58 does not induce the heat shock response (HSR). NCT-58 elicits anti-tumor activity via the simultaneous dow...
|
T21883 |
Gedunin
|
2753-30-2
|
98%
|
|
Gedunin is an important limonoid present in several genera of the Meliaceae family, mainly in seeds. Gedunin is an Hsp90 inhibitor, and inhibits ovarian cancer c...
|
T8858 |
DTHIB
|
897326-30-6
|
98%
|
|
DTHIB robustly inhibits the HSF1 cancer gene signature and prostate cancer cell proliferation.
|
T9202 |
DDO-5936
|
2355377-13-6
|
98%
|
|
DDO-5936 is a potent and specific HSP90-Cdc37 PPI inhibitor.
|
T1501 |
Rifabutin
|
72559-06-9
|
98%
|
|
Rifabutin inhibits bacterial DNA-dependent RNA polymerase, thereby suppressing the initiation of RNA formation and leading to inhibition of RNA synthesis and tra...
|
T13553 |
Arimoclomol
|
289893-25-0
|
98%
|
|
Arimoclomol is a co-inducer of heat shock proteins (HSP) and can be used in studies about the treatment of amyotrophic lateral sclerosis (ALS).
|
T2286 |
BIIB021
|
848695-25-0
|
98%
|
|
BIIB021 is an orally-available, fully synthetic inhibitor of HSP90(Ki=1.7 nM, EC50=38 nM).
|
T6609 |
NMS-E973
|
1253584-84-7
|
98%
|
|
NMS-E973 is a potent and selective Hsp90 inhibitor with DC50 of <10 nM for Hsp90 binding, no activiy against a panel of 52 diverse protein kinases.
|
T6284 |
Onalespib
|
912999-49-6
|
98%
|
|
Onalespib is a synthetic, orally bioavailable, small-molecule inhibitor of heat shock protein 90 (Hsp90) with potential antineoplastic activity. Onalespib select...
|
T2179 |
Triptolide
|
38748-32-2
|
98%
|
|
Triptolide is a diterpenes trioxide, immunosuppressive agent extracted from the Chinese herb Tripterygium wilfordii.
|
T6290 |
Tanespimycin
|
75747-14-7
|
98%
|
|
Tanespimycin (17-AAG) is an inhibitor of Hsp90 that selectively inhibits BT474 tumor cell Hsp90 (IC50: 5 nM).
|
T28824 |
SNX0723
|
1073969-18-2
|
98%
|
|
SNX0723 is a potent Hsp90 Inhibitor with anti-Plasmodium activity. SNX0723 shows high binding affinity for HsHsp90 and PfHsp90 with Kis of 4.4 and 47 nM, respect...
|
T6855 |
HA15
|
1609402-14-3
|
98%
|
|
HA15 targets specifically BiP/GRP78/HSPA5. HA15 exhibits anti-cancerous activity on all melanoma cells tested, including cells isolated from patients and cells t...
|
T2908 |
Palmitic acid
|
57-10-3
|
98%
|
|
Palmitic acid is the most common saturated fatty acid found in animals, plants and microorganisms with anti-tumor activity.
|
T3652 |
KRIBB11
|
342639-96-7
|
98%
|
|
KRIBB11 is an inhibitor of Heat shock factor (HSF) inhibitor.
|
T3454 |
VER-49009
|
558640-51-0
|
98%
|
|
VER-49009 is a potent Hsp90 inhibitor(IC50 of 25 nM and Kd of 78 nM).
|
T6297 |
Alvespimycin hydrochloride
|
467214-21-7
|
98%
|
|
17-DMAG is a potent HSP90 inhibitor with IC50 of 62 nM. Phase 2.
|
T2258 |
VER-50589
|
747413-08-7
|
98%
|
|
VER-50589 is a potent HSP90 inhibitor.
|