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Immunology/Inflammation related

Immunology is a branch of biology and medicine that covers the study of immune systems in all organisms. Inflammation is part of the complex biological response of body tissues to harmful stimuli, such as pathogens, damaged cells, or irritants, and is a protective response involving immune cells, blood vessels, and molecular mediators. Immunology/Inflammation related compound can target related diseases.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
TN4220 Homobutein 34000-39-0 99.50%
Homobutein
Homobutein (3-O-Methylbutein) is a dual inhibitor of HDACs and NF-κB with IC50s of 190 and 38 μM. Homobutein is an iron chelator with anticancer, anti-inflammato...
T64359 Anti-inflammatory agent 36 2293951-01-4 99.47%
Anti-inflammatory agent 36
Anti-inflammatory agent 36 is an anti-inflammatory agent. It exhibited dose-dependent inhibition of LPS-induced release of TNF-a and IL-6 in active RAW 264.7 mou...
T3834 8-Epideoxyloganic acid 88668-99-9 99.41%
8-Epideoxyloganic acid
8-Epideoxyloganic acid possesses bioactivities of analgesia, homeostasis and anti-inflammatory. It has the potential to serve as anti-inflammatory agents during ...
TN1705 Glycyrrhisoflavone 116709-70-7 99.4%
Glycyrrhisoflavone
Glycyrrhisoflavone is a tyrosinase inhibitor with anti-inflammatory effects. Glycyrrhisoflavone inhibits α-glucosidase and monoamine oxidase.
TN1455 Bryodulcosigenin 4965-97-3 99.24%
Bryodulcosigenin
Bryodulcosigenin has anti-inflammatory effect, it shows potent inhibitory effects on EBV-EA induction.
T23636 Adenosine N1-oxide 146-92-9 99.24%
Adenosine N1-oxide
Adenosine N1-oxide (1-Oxoadenosine), which is found in royal jelly, inhibited the secretion of inflammatory mediators by activated macrophages and reduced lethal...
TN1823 Kaempferol 3-O-β-D-galactopyranoside 23627-87-4 99.22%
Kaempferol 3-O-β-D-galactopyranoside
Kaempferol 3-O-β-D-galactopyranoside has antioxidant, anti-inflammatory and antinociceptive activities.
TN1039 Tamarixetin 603-61-2 99.21%
Tamarixetin
Tamarixetin (4'-O-Methyl Quercetin) (4'-O-Methyl Quercetin) is a natural flavonoid derivative of quercetin, with anti-inflammatory and anti-oxidative effects. Ta...
TN1961 Myricetin 3-O-glucoside 19833-12-6 99.17%
Myricetin 3-O-glucoside
Myricetin 3-O-glucoside (Myricetin 3-O-beta-D-glucopyranoside) is a flavonol extracted from Tibouchina paratropica. Myricetin 3-O-glucoside has many activities, ...
T3832 11-O-Galloylbergenin 82958-44-9 99.16%
11-O-Galloylbergenin
11-O-Galloylbergenin is isolated from of Mallotus philippinensis with antioxidant and antiplasmodial activities.
T14955 Chlorthenoxazine 132-89-8 99.10%
Chlorthenoxazine
Chlorthenoxazine (Chlorethylbenzmethoxazone) has anti-inflammatory activity.
TN1131 Handelin 62687-22-3 99.02%
Handelin
Handelin has anti-inflammatory activity by inhibiting NF-κB activation and pro-inflammatory cytokine productions.
TL0013 Heraclenin 2880-49-1 98.95%
Heraclenin
Heraclenin has anticoagulant, and anti-inflammatory activities, it also has mutagenicity in Chlamydomonas reinhardii. Heraclenin can induce apoptosis in Jurkat l...
TN1166 1,3,6-Tri-O-galloyl-beta-D-glucose 18483-17-5 98.94%
1,3,6-Tri-O-galloyl-beta-D-glucose
1,3,6-Tri-O-galloyl-beta-D-glucose (1,3,6-Tri-O-galloylglucose) is a phenolic compound in Black Walnut Kernels. It shows anti-inflammatory activity.
TN1599 Eburicoic acid 560-66-7 98.94%
Eburicoic acid
Eburicoic acid (ZINC4655149) exhibits anti-inflammatory and antioxidant activity thereby protecting the liver from CCl4-induced hepatic damage and can be used in...
T27654 JG26 1464910-32-4 98.92%
JG26
JG26 is a potent inhibitor of ADAM17, which can inhibit ADAM8, ADAM17, ADAM10 and MMP-12, with IC50 values of 12 nM, 1.9 nM, 150 nM and 9.4 nM, respectively, and...
T9748 Anti-inflammatory agent 34 867301-81-3 98.82%
Anti-inflammatory agent 34
Anti-inflammatory agent 34 shows moderate acute anti-inflammatory activity and analgesic activity in vivo.
TN1249 3-Epiursolic acid 989-30-0 98.81%
3-Epiursolic acid
3-Epiursolic acid may have antiinflammatory activity, it shows inhibition on Cathepsins L (catL), the IC50 value of 6.5 μM, cathepsins L (catL) and B play an imp...
T7522 GI254023X 260264-93-5 98.56%
GI254023X
GI254023X is a potent MMP9 and ADAM10 inhibitor (IC50s: 2.5 and 5.3 nM) with 100-fold selectivity for the α-secretase ADAM10 over ADAM17 (TACE). GI254023X can re...
TN1475 Caulophyllogenin 52936-64-8 98.56%
Caulophyllogenin
Caulophyllogenin is a partial PPARγ agonist (EC50 = 12.6 μM) derived from the stem bark of Kalopanax pictus (Araliaceae). Caulophyllogenin inhibits pro-inflammat...
Homobutein
TN4220
Homobutein (3-O-Methylbutein) is a dual inhibitor of HDACs and NF-κB with IC50s of 190 and 38 μM. Homobutein is an iron chelator with anticancer, anti-inflammato...
Anti-inflammatory agent 36
T64359
Anti-inflammatory agent 36 is an anti-inflammatory agent. It exhibited dose-dependent inhibition of LPS-induced release of TNF-a and IL-6 in active RAW 264.7 mou...
8-Epideoxyloganic acid
T3834
8-Epideoxyloganic acid possesses bioactivities of analgesia, homeostasis and anti-inflammatory. It has the potential to serve as anti-inflammatory agents during ...
Glycyrrhisoflavone
TN1705
Glycyrrhisoflavone is a tyrosinase inhibitor with anti-inflammatory effects. Glycyrrhisoflavone inhibits α-glucosidase and monoamine oxidase.
Bryodulcosigenin
TN1455
Bryodulcosigenin has anti-inflammatory effect, it shows potent inhibitory effects on EBV-EA induction.
Adenosine N1-oxide
T23636
Adenosine N1-oxide (1-Oxoadenosine), which is found in royal jelly, inhibited the secretion of inflammatory mediators by activated macrophages and reduced lethal...
Kaempferol 3-O-β-D-galactopyranoside
TN1823
Kaempferol 3-O-β-D-galactopyranoside has antioxidant, anti-inflammatory and antinociceptive activities.
Tamarixetin
TN1039
Tamarixetin (4'-O-Methyl Quercetin) (4'-O-Methyl Quercetin) is a natural flavonoid derivative of quercetin, with anti-inflammatory and anti-oxidative effects. Ta...
Myricetin 3-O-glucoside
TN1961
Myricetin 3-O-glucoside (Myricetin 3-O-beta-D-glucopyranoside) is a flavonol extracted from Tibouchina paratropica. Myricetin 3-O-glucoside has many activities, ...
11-O-Galloylbergenin
T3832
11-O-Galloylbergenin is isolated from of Mallotus philippinensis with antioxidant and antiplasmodial activities.
Chlorthenoxazine
T14955
Chlorthenoxazine (Chlorethylbenzmethoxazone) has anti-inflammatory activity.
Handelin
TN1131
Handelin has anti-inflammatory activity by inhibiting NF-κB activation and pro-inflammatory cytokine productions.
Heraclenin
TL0013
Heraclenin has anticoagulant, and anti-inflammatory activities, it also has mutagenicity in Chlamydomonas reinhardii. Heraclenin can induce apoptosis in Jurkat l...
1,3,6-Tri-O-galloyl-beta-D-glucose
TN1166
1,3,6-Tri-O-galloyl-beta-D-glucose (1,3,6-Tri-O-galloylglucose) is a phenolic compound in Black Walnut Kernels. It shows anti-inflammatory activity.
Eburicoic acid
TN1599
Eburicoic acid (ZINC4655149) exhibits anti-inflammatory and antioxidant activity thereby protecting the liver from CCl4-induced hepatic damage and can be used in...
JG26
T27654
JG26 is a potent inhibitor of ADAM17, which can inhibit ADAM8, ADAM17, ADAM10 and MMP-12, with IC50 values of 12 nM, 1.9 nM, 150 nM and 9.4 nM, respectively, and...
Anti-inflammatory agent 34
T9748
Anti-inflammatory agent 34 shows moderate acute anti-inflammatory activity and analgesic activity in vivo.
3-Epiursolic acid
TN1249
3-Epiursolic acid may have antiinflammatory activity, it shows inhibition on Cathepsins L (catL), the IC50 value of 6.5 μM, cathepsins L (catL) and B play an imp...
GI254023X
T7522
GI254023X is a potent MMP9 and ADAM10 inhibitor (IC50s: 2.5 and 5.3 nM) with 100-fold selectivity for the α-secretase ADAM10 over ADAM17 (TACE). GI254023X can re...
Caulophyllogenin
TN1475
Caulophyllogenin is a partial PPARγ agonist (EC50 = 12.6 μM) derived from the stem bark of Kalopanax pictus (Araliaceae). Caulophyllogenin inhibits pro-inflammat...
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TargetMol