MMP

Matrix metallopeptidases (MMPs), also known as matrix metalloproteinases or matrixins, are metalloproteinases that are calcium-dependent zinc-containing endopeptidases; other family members are adamalysins, serralysins, and astacins. The MMPs belong to a larger family of proteases known as the metzincin superfamily.

Cat. No.	Product name	CAS No.	Purity
T7449	O-Phenanthroline monohydrate	5144-89-8	99.15%
T7449	o-Phenanthroline monohydrate (1, 10-Phenanthroline monohydrate) is an inhibitor of metallopeptidases, inhibits zinc-dependent hydrolysis of Fa-Gly-Leu-NH2 by B. ...
T61271	MMP2-IN-3	897799-81-4	99.13%
T61271	MMP2-IN-3 is a potent inhibitor of matrix metalloproteinases (MMP-2) (IC50: 31 μM). MMP2-IN-3 inhibits MMP-9 and MMP-8 with IC50s of 26.6 and 32 μM, respectively...
T3860	Isoliquiritin apioside	120926-46-7	99.01%
T3860	Isoliquiritin apioside, isolated from Glycyrrhizae radix rhizome, significantly decreases PMA-induced increases in MMP9 activities and suppresses PMA-induced act...
T27654	JG26	1464910-32-4	98.92%
T27654	JG26 is a potent inhibitor of ADAM17, which can inhibit ADAM8, ADAM17, ADAM10 and MMP-12, with IC50 values of 12 nM, 1.9 nM, 150 nM and 9.4 nM, respectively, and...
T2834	Nobiletin	478-01-3	98.88%
T2834	Nobiletin (Hexamethoxyflavone) is a natural polymethoxylated flavone isolated from citrus peels with anti-inflammatory and anti-tumor activities. Nobiletin is pr...
T8259	Doxycycline monohydrate	17086-28-1	98.87%
T8259	Doxycycline monohydrate is an inhibitor of metalloproteinase (MMP)
T37048	MMP-3 Inhibitor	158841-76-0	98.87%
T37048	MMP-3 Inhibitor is a peptide matrix metalloproteinase-3 (MMP-3) inhibitor with a Ki value of 95 nM.MMP-3 inhibitor has anticancer and antitumor activity.
T2973	Astragaloside IV	84687-43-4	98.85%
T2973	Astragaloside IV (AS-IV), an active component isolated from Astragalus membranaceus, suppresses the activation of ERK1/2 and JNK, and downregulates matrix metall...
T2987	(-)-Epigallocatechin	970-74-1	98.83%
T2987	(-)-Epigallocatechin, the predominant flavonoid in green tea, possesses the unique ability to attach to unfolded native polypeptides, thereby inhibiting their tr...
TN6784	Ethyl rosmarinate	174591-47-0	98.82%
TN6784	Methyl rosmarinate (Methyl rosmarinate) inhibit the activity of tyrosinase, α-glucosidase, and matrix metalloproteinase-1 (MMP-1).
TP1741L	Histatin 5 acetate	TP1741L	98.72%
TP1741L	Histatin 5 acetate inhibits the activity of the host matrix metalloproteinases MMP-2 and MMP-9 with IC50s of 0.57 and 0.25 μM, respectively.
T4S0181	Hinokiflavone	19202-36-9	98.67%
T4S0181	Hinokiflavone, a novel modulator of pre-mRNA splicing activity both in vitro and in cellulo, inhibits the assembly of the spliceosome, particularly blocking the ...
T7522	GI254023X	260264-93-5	98.56%
T7522	GI254023X is a potent MMP9 and ADAM10 inhibitor (IC50s: 2.5 and 5.3 nM) with 100-fold selectivity for the α-secretase ADAM10 over ADAM17 (TACE). GI254023X can re...
T6011	Batimastat	130370-60-4	98.55%
T6011	Batimastat (BB94) (BB-94) is an effective, broad-spectrum matrix metalloprotease (MMP) inhibitor. Batimastat induces extracellular matrix degradation and inhibit...
T14322	ARP-100	704888-90-4	98.34%
T14322	ARP-100 (MMP-2 Inhibitor III) is a potent and selective matrix metalloproteinase MMP-2 inhibitor (IC50=12 nM). ARP-100 interacts with the S1' pocket of MMP-2 and...
T6S0444	Salvianolic acid A	96574-01-5	98.31%
T6S0444	Salvianolic acid A (Dan Phenolic Acid A) could protect the blood brain barrier through inhibition of matrix metallopeptidase 9 (MMP-9) and anti-inflammation.
T3S0640	Triolein	122-32-7	98.28%
T3S0640	Glyceryl Trioleate has been investigated for the treatment of Adrenoleukodystrophy.
T28145	ND-322 HCl	1333379-23-9	98.14%
T28145	ND-322 HCl (ND 322 Hydrochloride) is a selective inhibitor of MT1-MMP and MMP2 and reduces in vitro melanoma cell growth, migration and invasion.
T6885	Marimastat	154039-60-8	98.11%
T6885	Marimastat (BB2516) (BB-2516) is a potent, broad spectrum matrix metalloprotease (MMP) inhibitor. MMP-9 (IC50=3 nM), MMP-1 (IC50=5 nM), MMP-2 (IC50=6 nM), MMP-14...
T3767	Polygalacic acid	22338-71-2	98.11%
T3767	Polygalacic acid (Virgaureagenin G)(PA) significantly improves cholinergic system reactivity, as indicated by decreased acetylcholinesterase (AChE) activity, inc...