Nucleoside Antimetabolite/Analog

Nucleoside analogues are molecules that act like nucleosides in DNA synthesis. They include a range of antiviral products used to prevent viral replication in infected cells. Nucleoside analogues can be used against hepatitis B virus, hepatitis C virus, herpes simplex, and HIV. Once they are phosphorylated, they work as antimetabolites by being similar enough to nucleotidesto be incorporated into growing DNA strands.

Cat. No.	Product name	CAS No.	Purity
TQ0006	Ethynylcytidine	180300-43-0	98%
TQ0006	Ethynylcytidine is a nucleoside antimetabolite.
T15378	Gemcitabine elaidate	210829-30-4	98%
T15378	Gemcitabine elaidate, is a lipophilic, unsaturated fatty acid ester derivative of gemcitabine (dFdC), an antimetabolite deoxynucleoside analogue, with potential ...
T65979	Adenosine 5'-monophosphate disodium salt	4578-31-8	98%
T65979	Adenosine 5'-monophosphate disodium salt is a purine nucleotide involved in ATP metabolism and is used to study the effects of ATP on cells and organisms. Adenos...
T5539	GS-443902	1355149-45-9	98%
T5539	GS-441524 was shown to be a safe and effective treatment for feline infectious peritonitis (FIP). The optimum dosage was found to be 4.0 mg/kg SC q24h for at lea...
TQ0245	Sapacitabine	151823-14-2	98%
TQ0245	Sapacitabine is a nucleoside analog prodrug with antitumor activity.
T38236	2′-Deoxy-2′-fluoroguanosine	78842-13-4	98%
T38236	2′-Deoxy-2′-fluoroguanosine, a nucleoside analog, is a potent inhibitor of influenza virus strains, with an EC90 of <0.35 μM for influenza virus A and B strains....
T38238	2'-Deoxy-2'-fluorocytidine	10212-20-1	98%
T38238	2'-Deoxy-2'-fluorocytidine, an nucleoside analog, is a potent inhibitor of Crimean-Congo hemorrhagic fever virus (CCHFV) replication. 2′-deoxy-2′-fluorocytidine ...
T36572	N6-Methyladenine	443-72-1	98%
T36572	N6-Methyladenine is a modified purine commonly found in genomes of prokaryotes, protists, and plants. N6-methyladenine affects diverse DNA functions, including r...
T19083	1-Methylinosine	2140-73-0	98%
T19083	1-Methylinosine is a modified nucleotide found at position 37 in tRNA 3' to the anticodon of eukaryotic tRNA.
T13659	DMTr-LNA-5MeU-3-CED-phosphoramidite	206055-75-6	98%
T13659	DMTr-LNA-5MeU-3-CED-phosphoramidite is a nucleoside derivative.
T15235	Enocitabine	55726-47-1	98%
T15235	Enocitabine, a nucleoside analog, is a potent DNA replication inhibitor and a DNA chain terminator. Enocitabine inhibits the replication of human cytomegalovirus...
T0010	6-Mercaptopurine	50-44-2	98%
T0010	Mercaptopurine is an antimetabolite antineoplastic agent with immunosuppressant properties. It interferes with nucleic acid synthesis by inhibiting purine metabo...
T38958	DMT-2′Fluoro-dU Phosphoramidite	146954-75-8	98%
T38958	DMT-2′Fluoro-dU Phosphoramidite can be used to modify nucleosides.
T9727	2'-Fluoro-2'-Deoxyadenosine	64183-27-3	98%
T9727	2'-Fluoro-2'-Deoxyadenosine is efficiently cleaved to the toxic 2-fluoroadenine (FAde) by Escherichia coli purine nucleoside phosphorylase (PNP). 2'-Fluoro-2'-De...
T20102	8-Azahypoxanthine	2683-90-1	98%
T20102	8-Azahypoxanthine is an antimalarial. It inhibits hypoxanthine-guanine-xanthine phosphoribosyltransferase.
T38237	2′-O-Methylcytidine	2140-72-9	98%
T38237	2'-O-Methylcytidine is a nucleoside derivative and an inhibitor of hepatitis C virus (HCV) non-structural protein 5B (NS5B; IC50= 3.8 μM).1It inhibits HCV replic...
T9726	2’-OMe-Guanosine	2140-71-8	98%
T9726	2'-OMe-Guanosine is a modified nucleoside produced by the action of tRNA guanosine-2'-o-methyltransferase. 2'-OMe-Guanosine has a certain pro-apoptotic effect.
T36866	3-Deazauridine	23205-42-7	98%
T36866	3-Deazauridine is a structural analog of uridine that inhibits the biosynthesis of Cytidine-5'-Triphosphate by competitive inhibition of Cytidine Triphosphate sy...
T40192	DGTP	2564-35-4	98%
T40192	dGTP is one of the guanosine nucleotides which is highly susceptible to oxidative damage to 8-O-GDP, 8-O-dGTP, 8-O-GTP, and 8-O-dGTP.
T36944	Ara-G	38819-10-2	98%
T36944	Ara-G is an analog of the nucleoside guanosine and an active metabolite of nelarabine .1,2 Ara-G accumulates in T lymphoblasts and malignant T-lymphoid cells, wh...