Nucleoside Antimetabolite/Analog

Nucleoside analogues are molecules that act like nucleosides in DNA synthesis. They include a range of antiviral products used to prevent viral replication in infected cells. Nucleoside analogues can be used against hepatitis B virus, hepatitis C virus, herpes simplex, and HIV. Once they are phosphorylated, they work as antimetabolites by being similar enough to nucleotidesto be incorporated into growing DNA strands.

Cat. No.	Product name	CAS No.	Purity
TNU0007	3'-Deoxy-3'-fluoroadenosine	75059-22-2	99.84%
TNU0007	3'-Deoxy-3'-fluoroadenosine is a purine nucleoside analogue with a wide range of anti-tumor and anti-viral activity, and has inhibitory effects on tick-borne enc...
T0984	5-Fluorouracil	51-21-8	99.83%
T0984	5-Fluorouracil (5-FU) is a uracil analog, an inhibitor of DNA synthesis. 5-Fluorouracil has antitumor activity and affects pyrimidine synthesis through inhibitio...
T3658	Trifluridine/tipiracil hydrochloride mixture	733030-01-8	99.82%
T3658	Trifluridine/tipiracil hydrochloride mixture (TAS-102) is a novel oral combination drug containing trifluridine (TFT) and Tipiracil hydrochloride (TTP) in a mola...
T1339	5-Azacytidine	320-67-2	99.78%
T1339	5-Azacytidine (Ladakamycin) is a cytidine nucleoside analog, a DNA methylation inhibitor with specificity. 5-Azacytidine regulates gene expression by decreasing ...
TNU0355	N6-Methyl-2'-O-methyladenosine	57817-83-1	99.77%
TNU0355	N6-Methyl-2'-O-methyladenosine (N6,2′-O-Dimethyladenosine), a substrate for adiposity and obesity-related genes (FTO), is a reversible modifier compound found on...
T13621	CNDAC hydrochloride	134665-72-8	99.69%
T13621	CNDAC hydrochloride, a nucleoside analog, is a metabolite of the sapacitabine.
T0251	Gemcitabine	95058-81-4	99.67%
T0251	Gemcitabine (LY188011) is a synthetic cytosine nucleoside derivative and an inhibitor of DNA synthesis. Gemcitabine has antitumor and antimetabolic activities. G...
TNU1205	2’-Deoxy-N4-methylcytidine	22882-02-6	99.61%
TNU1205	2’-Deoxy-N4-methylcytidine (N(3)-Methyl-2'-deoxycytidine) is a purine nucleoside analog with potential antitumor activity for the study of apoptosis.
T38251	L-Uridine	26287-69-4	99.57%
T38251	L-Uridine is the enantiomer of D-uridine, a nucleoside that acts as a phosphate acceptor for nucleoside phosphotransferase, in the normal RNA component of a norm...
T0688	Ganciclovir	82410-32-0	99.55%
T0688	Ganciclovir (2'-Nor-2'-deoxyguanosine) is an ACYCLOVIR analog that is a potent inhibitor of the Herpesvirus family including cytomegalovirus. Ganciclovir is used...
TNU0266	9-(β-D-Xylofuranosyl)adenine	524-69-6	99.55%
TNU0266	9-(β-D-Xylofuranosyl)adenine (Adenine xyloside) is an adenine nucleoside analog that is a potential smooth muscle vasodilator.9-(β-D-Xylofuranosyl)adenine has an...
T16813	RX-3117	865838-26-2	99.55%
T16813	RX-3117 (fluorocyclopentenylcytosine) is a novel a cytidine analog. RX-3117 displays anticancer activity in several cancer cell lines, including gemcitabine-resi...
T1408	Capecitabine	154361-50-9	99.53%
T1408	Capecitabine (Capecitibine) is a fluoropyrimidine carbamate belonging to the class of antineoplastic agents called antimetabolites. As a prodrug, capecitabine is...
T36687	Ac-rC Phosphoramidite	121058-88-6	99.49%
T36687	Ac-rC Phosphoramidite can modify phosphodisulfide oligonucleotides.
T22337	Ganciclovir sodium	107910-75-8	99.47%
T22337	Ganciclovir sodium (Cytovene IV sodium) is the sodium salt of Ganciclovir with antiviral activity, especially against cytomegalovirus (CMV) and herpes simplex vi...
T2366	Tipiracil hydrochloride	183204-72-0	99.45%
T2366	Tipiracil hydrochloride (MA-1 hydrochloride) is a thymidine phosphorylase inhibitor (TPI). Tipiracil hydrochloride is one of the active components in TAS-102, wh...
TNU0541	8-Azaguanosine	2133-80-4	99.44%
TNU0541	8-Azaguanosine is a purine nucleoside analog with a broad spectrum of antitumor activity and is used in the study of a variety of tumor diseases.
TNU0085	2'-Deoxy-2'-fluoroarabinoadenosine	20227-41-2	99.44%
TNU0085	2'-Deoxy-2'-fluoroarabinoadenosine is a nucleoside analogue with extensive anti-tumor activity and can be used for the study of tumor diseases.
T19464	N6,N6-Dimethyladenosine	2620-62-4	99.42%
T19464	N6,N6-Dimethyladenosine is find in mycobacterium bovis Bacille Calmette-Guérin tRNA.
T4061	LY2334737	892128-60-8	99.4%
T4061	LY2334737 is an orally available prodrug of gemcitabine with antineoplastic activity.