Nucleoside Antimetabolite/Analog

Nucleoside analogues are molecules that act like nucleosides in DNA synthesis. They include a range of antiviral products used to prevent viral replication in infected cells. Nucleoside analogues can be used against hepatitis B virus, hepatitis C virus, herpes simplex, and HIV. Once they are phosphorylated, they work as antimetabolites by being similar enough to nucleotidesto be incorporated into growing DNA strands.

Cat. No.	Product name	CAS No.	Purity
T0532	5,6-Dihydro-5-methyluracil	696-04-8	99.37%
T0532	5,6-Dihydro-5-methyluracil (Dihydrothymine) is an intermediate breakdown product of thymine.
TNU1431	(S)-GNA-T-phosphoramidite	168332-13-6	99.35%
TNU1431	(S)-GNA-T-phosphoramidite is a nucleoside analog commonly used in the synthesis of other active compounds.
TNU0091	3'-Deoxy-3'-fluoroguanosine	123402-21-1	99.33%
TNU0091	3'-Deoxy-3'-fluoroguanosine is a nucleoside phosphorylase inhibitor that inhibits RNA replication by binding replons. 3 '-Deoxy-3' -fluoroguanosine is used to tr...
T14329	Ascamycin	91432-48-3	99.29%
T14329	Ascamycin is a 5'-O-sulfonamide ribonucleoside antibiotic produced by Streptomyces spp. It shows selective antibacterial activity against Xanthomonas species and...
T12399	Peldesine	133432-71-0	99.27%
T12399	Peldesine (BCX 34) is an effective, competitive, reversible, and orally active inhibitor of purine nucleoside phosphorylase. Peldesine inhibits T-cell proliferat...
T6501	Fludarabine Phosphate	75607-67-9	99.25%
T6501	Fludarabine Phosphate (NSC 312887 Phosphate) is the phosphate salt of a fluorinated nucleotide antimetabolite analog of the antiviral agent vidarabine (ara-A) wi...
T65979	Adenosine 5'-monophosphate disodium salt	4578-31-8	99.24%
T65979	Adenosine 5'-monophosphate disodium salt (Adenosine Phosphate Disodium) is a purine nucleotide involved in ATP metabolism and is used to study the effects of ATP...
T1508	Decitabine	2353-33-5	99.17%
T1508	Decitabine (Deoxycytidine) is a deoxycytidine analog, a DNA methyltransferase inhibitor with oral activity. Decitabine has antitumor activity and antimetabolic a...
T1404	Stavudine	3056-17-5	99.15%
T1404	Stavudine (BMY-27857), a nucleoside reverse transcriptase inhibitor analog of thymidine, has activity against HIV.
T12908	SIBA	35899-54-8	99.15%
T12908	SIBA (5'-Deoxy-5'-isobutylthioadenosine) is a synthetic analogue of SAH, acts as an inhibitor of S-adenosylmethionine-mediated transmethylation. SIBA can interfe...
TNU0810	2′-C-Methyl-6-O-methylinosine	565450-78-4	99.09%
TNU0810	2′-C-Methyl-6-O-methylinosine (2′-C-Methyl-6-O-methylinosine) is a hypoxanthine analog with a wide range of physical activities for the study of a variety of tum...
T6632	Raltitrexed	112887-68-0	99.06%
T6632	Raltitrexed (D1694)(IC50 of 9 nM), a thymidylate synthase inhibitor, is used for the inhibition of L1210 cell growth.
T2201	6-Mercaptopurine hydrate	6112-76-1	99%
T2201	6-Mercaptopurine hydrate (6-Mercaptopurine monohydrate) is a Nucleoside Metabolic Inhibitor. It interferes with nucleic acid synthesis by inhibiting purine metab...
TNU0031	5-Hydroxyuridine	957-77-7	98.76%
TNU0031	5-Hydroxyuridine (OHUrd) is a purine nucleoside analogue with potential antitumour activity, showing cytotoxicity against human colon adenocarcinoma cell lines.
T36688	Deoxyguanosine triphosphate trisodium salt	93919-41-6	98.73%
T36688	Deoxyguanosine triphosphate trisodium salt (2'-Deoxyguanosine-5'-triphosphate trisodium salt) is a nucleotide precursor for DNA synthesis in cells and can be use...
T2218	8-Azaguanine	134-58-7	98.66%
T2218	8-Azaguanine (SK 1150) is a purine analogue with potential antineoplastic activity.
T32826	LNA-Adenosine	206055-70-1	98.62%
T32826	LNA-Adenosine (LNA-A) is a nucleoside analogue that acts as a ligand for adenosine A3 receptors.
TNU0436	2-Thiocytidine	13239-97-9	98.59%
TNU0436	2-Thiocytidine is a purine nucleoside analog that targets malignant tumors of the inert lymphatic system and has a broad spectrum of antitumor activity.2-Thiocyt...
TNU1119	N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite	207347-42-0	98.59%
TNU1119	N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite is an adenine nucleoside analog with potential vasodilator activity and anticancer activity for cancer...
T1307	Carmofur	61422-45-5	98.59%
T1307	Carmofur (HCFU) is a highly potent acid ceramidase inhibitor, used in the treatment of breast and colorectal cancer. Carmofur has been known to induce leukoencep...