T3208 |
Brevianamide F
|
38136-70-8
|
97.30%
|
|
Brevianamide F (Cyclo(L-Pro-L-Trp)), also known as cyclo-(L-Trp-L-Pro), belongs to a class of naturally occurring 2,5-diketopiperazines. Brevianamide F possess i...
|
T1826 |
PI3K-IN-1
|
1349796-36-6
|
97.07%
|
|
PI3K-IN-1 (Voxtalisib Analogue) is a dual inhibitor of mTOR/PI3K, mostly for p110γ , also inhibits DNA-PK and mTOR.
|
T7015 |
Vps34-IN-1
|
1383716-33-3
|
97.04%
|
|
Vps34-IN-1 (VPS34-IN1) is a potent and highly selective Vps34 inhibitor with IC50 of 25 nM in vitro, which does not significantly inhibit the isoforms of class I...
|
T6630 |
Quercetin Dihydrate
|
6151-25-3
|
97.03%
|
|
Quercetin Dihydrate (Sophoretin) is a polyphenolic flavonoid that was found in a wide variety of plant-based foods, such as apples, onions, berries, and red wine...
|
T3190 |
PIK-inhibitors
|
371934-59-7
|
96.98%
|
|
PIK-inhibitors (MDK34597) is a pan PI3K inhibitors, an analog of PI-103.
|
TN1153 |
Polyporenic acid C
|
465-18-9
|
96.84%
|
|
Polyporenic acid C shows inhibitory activity against human collagenase.
|
TN1405 |
Arnicolide D
|
34532-68-8
|
96.66%
|
|
Arnicolide D is a sesquiterpene lactone. Arnicolide D isolates from Centipeda minima. Arnicolide D modulates the cell cycle, activates the caspase signaling path...
|
T11593 |
I-OMe-Tyrphostin AG 538
|
1094048-77-7
|
96.66%
|
|
I-OMe-Tyrphostin AG 538 is a specific IGF-1R inhibitor and ATP-competitive inhibitor of PI5P4Kα (IC50: 1 µM).I-OMe-Tyrphostin AG 538 inhibits IGF-1R-mediated sig...
|
T6817 |
Deguelin
|
522-17-8
|
96.39%
|
|
Deguelin ((-)-Deguelin) is a PI3K/AKT Inhibitor, which is a natural product isolated from plants in the Mundulea sericea family.
|
T6072L |
BGT226
|
915020-55-2
|
95.74%
|
|
BGT226 (NVP-BGT226) is a novel dual PI3K / mTOR inhibitor, it acts on PI3K α/β/γ with IC50 of 4 nM / 63 nM / 38 nM, respectively.
|
T13140 |
Umbralisib R-enantiomer
|
1532533-69-9
|
95.61%
|
|
Umbralisib R-enantiomer (RP5264 R-enantiomer) is a delta inhibitor of PI3K and a less active enantiomer of TGR-1202. The IC50 of Umbralisib R-enantiomers against...
|
T2836 |
Isorhamnetin
|
480-19-3
|
92.82%
|
|
Isorhamnetin (3-methylquercetin) is the methylated metabolite of quercetin. Quercetin is an important dietary flavonoid with in vitro antioxidant activity. Isorh...
|
T3541 |
CC-115
|
1228013-15-7
|
86.79%
|
|
CC-115 is a inhibitor of mTOR/DNA-PK (IC50= 21/ 13 nM).
|
T4199 |
Desmethyl-VS-5584
|
1246535-95-4
|
100%
|
|
Desmethyl-VS-5584 is a dimethyl analog of VS-5584, which is a novel and highly selective PI3K/mTOR kinase inhibitor for the treatment of cancer.
|
T1056 |
Isoprenaline hydrochloride
|
51-30-9
|
100%
|
|
Isoprenaline hydrochloride (NCI-c55630) is a potent beta-adrenergic agonist with the peripheral vasodilator, bronchodilator, and cardiac stimulating properties.
|
T2660 |
IC-87114
|
371242-69-2
|
100%
|
|
IC-87114 is a specific PI3Kδ inhibitor(IC50=0.5 μM).
|
T14511 |
BAY1082439
|
1375469-38-7
|
100%
|
|
BAY1082439 is highly effective in inhibiting Pten-null prostate cancer growth[1][2] and it is an orally bioavailable, selective PI3Kα/β/δ inhibitor. BAY1082439 a...
|
T3656 |
PKI-402
|
1173204-81-3
|
100%
|
|
PKI-402 is a potent PI3K and mTOR inhibitor. PKI-402 inhibits PI3Kα, mTOR, PI3Kβ, PI3Kδ and PI3Kγ with IC50s of 2, 3, 7, 14 and 16 nM, respectively.
|
T2433 |
NU 7026
|
154447-35-5
|
100%
|
|
NU 7026 (DNA-PK Inhibitor II) is an effective DNA-PK inhibitor (IC50: 0.23 μM, in cell-free assays), 60-fold selective for DNA-PK than PI3K and no inhibition aga...
|
T7879 |
TASP0415914
|
1292300-75-4
|
100%
|
|
TASP0415914 is an orally potent inhibitor of phosphoinositide 3-kinase γ (PI3Kγ). T
|