T81467 |
PI3Kδ-IN-18
|
|
98%
|
|
Se15, a selective PI3Kδ inhibitor, exhibits potency with an IC50 value of less than 0.1nM and is utilized in autoimmune research [1].
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T81468 |
PI3Kδ-IN-17
|
2768181-63-9
|
98%
|
|
PI3Kδ-IN-17 (Compound S5) is a potent PI3K δ inhibitor, exhibiting an IC50 value of 2.82 nM and demonstrates significant efficacy in suppressing the proliferatio...
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T81469 |
PI3Kα-IN-14
|
|
98%
|
|
PI3Kα-IN-14 (compound F8), a potent PI3Kα inhibitor, exhibits an IC50 value of 0.14 nM and markedly diminishes mitochondrial membrane potential, resulting in ce...
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T81470 |
PI3K/mTOR Inhibitor-14
|
2919684-77-6
|
98%
|
|
PI3K/mTOR Inhibitor-14 (compound Y-2) serves as a dual inhibitor of PI3K and mTOR, exhibiting IC50 values of 171.4 nM and 10.1 nM , respectively, and demonstrat...
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T81499 |
PH14
|
|
98%
|
|
PH14, a dual PI3K/HDAC inhibitor, demonstrates potent inhibition with IC50 values of 20.3 nM for PI3Kα and 24.5 nM for HDAC3. It exhibits antiproliferative eff...
|
TN4263 |
Isoangustone A
|
129280-34-8
|
98%
|
|
Isoangustone A has antitumor activity, it can induce G1 cycle arrest in DU145 human prostate and 4T1 murine mammary cancer cells, it inhibits cell proliferation ...
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T12460 |
PI3K/mTOR Inhibitor-1
|
1949802-49-6
|
98%
|
|
PI3K/mTOR Inhibitor-1 is a potent, orally bioavailable dual inhibitor of PI3K/mTOR (PI3Kα/PI3Kβ/PI3Kδ/PI3Kγ/mTOR with IC50s of 20/376/204/46/186 nM)
|
T12461 |
PI3Kdelta inhibitor 1
|
2242109-74-4
|
98%
|
|
PI3Kdelta inhibitor 1 is a potent, selective and orally available inhibitor of PI3Kδ with an IC50 of 1.3 nM.
|
TN1376 |
α-Solanine
|
20562-02-1
|
98%
|
|
Alpha-Solanine alters antioxidative enzyme activities and MDA and PCO concentrations and GST activity in fat body and midgut.
|
TN3691 |
Communic acid
|
2761-77-5
|
98%
|
|
Communic acid has antibacterial activity, including against mycobacterial. trans-Communic acid has potential to be utilized as anti-wrinkling agents and cosmetic...
|
TN4652 |
Niazimicin
|
147821-49-6
|
98%
|
|
Niazimicin are NF-B and PI3K inhibitors, which shows antimicrobial, hypotensive and spasmolytic activities. Niazimicin has potent antitumor promoting activity in...
|
T13389 |
ZD-0892
|
171964-73-1
|
98%
|
|
ZD-0892 is a selective and poten neutrophil elastaset inhibitor(human neutrophil elastase and porcine pancreatic elastase with Kis of 6.7 and 200 nM, respectivel...
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T28297 |
Parsaclisib hydrochloride
|
1995889-48-9
|
98%
|
|
Parsaclisib hydrochloride (INCB050465 HCl) is a selectve PI3Kδ inhibitor with antitumor activity. Parsaclisib demonstrates potent activity with IC50 values rangi...
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T6850 |
GSK2292767
|
1254036-66-2
|
98%
|
|
GSK2292767 is a potent and selective PI3Kδ inhibitor.
|
T2S0606 |
Bakkenolide A
|
19906-72-0
|
98%
|
|
Bakkenolide A has antifeedant and growth inhibitory effects on neonate variegated cutworms, it inhibits leukemia by regulation of HDAC3 and PI3K/Akt-related sign...
|
TN1347 |
8-Prenylkaempferol
|
28610-31-3
|
98%
|
|
8-Prenylkaempferol is an effective agent for attenuating pro-inflammatory NO induction, it may be an anti-inflammatory agent for suppressing influenza A virus-in...
|
TQ0313 |
NVP-BAG956
|
853910-02-8
|
98%
|
|
NVP-BAG956 is an ATP-competitive PI3K inhibitor (IC50s: 34/56/112/444 nM for PI3Kδ/PI3Kα/PI3Kγ/PI3Kβ).
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T10660L |
CAL-130 Hydrochloride
|
1431697-78-7
|
98%
|
|
CAL-130 Hydrochloride is a PI3Kδ and PI3Kγ inhibitor (IC50s: 1.3 and 6.1 nM).
|
TN2328 |
Zeylenone
|
193410-84-3
|
98%
|
|
Zeylenone, a cyclohexene oxide from Uvaria grandiflora, has antitumour and antiproliferative activity, inhibiting cervical cancer cell proliferation and inducing...
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TQ0003L |
740 Y-P(TFA)(1236188-16-1 free base)
|
TQ0003L
|
98%
|
|
740 Y-P(TFA)(1236188-16-1 free base) (740YPDGFR(TFA)) is a potent and cell-permeable activator of PI3K.
|