TN1367 |
Alismol
|
87827-55-2
|
98%
|
|
Alismol has antihypertensive action, it decreases cardiac output, heart rate and left ventricular pressure, but it increases coronary flow, it has been used for ...
|
T12457 |
PI3K-IN-6
|
1842380-77-1
|
98%
|
|
PI3K-IN-6 is an oral active and highly selective inhibitor of phosphoinositide 3-kinase (PI3K) β/δ(IC50 values of 7.8 nM/5.3 nM , respectively).
|
T12456 |
PI3K-IN-10
|
2211922-64-2
|
98%
|
|
PI3K-IN-10 is a potent inhibitor of pan-PI3K .
|
T10660 |
CAL-130
|
1431697-74-3
|
98%
|
|
CAL-130 is a PI3Kδ and PI3Kγ inhibitor (IC50s: 1.3 and 6.1 nM).
|
T12275 |
NVP-QAV-572
|
957209-68-6
|
98%
|
|
NVP-QAV-572 is a inhibitor of PI3K(IC50 of 10 nM).
|
TN1504 |
Citreorosein
|
481-73-2
|
98%
|
|
Citreorosein is a cAMP phosphodiesterase inhibitor, it has anti-inflammatory effect, inhibits proinflammatory cytokines production through the inhibition of both...
|
TMA0291 |
Dehydroglyasperin D
|
517885-72-2
|
98%
|
|
Dehydroglyasperin D exhibits anticancer, anti-inflammatory, anti-obesity, antioxidant and anti-aldose reductase effects, it inhibits the proliferation of HT-29 h...
|
TN3726 |
Cudraflavone B
|
19275-49-1
|
98%
|
|
Cudraflavone B has anti-proliferative activity, mouse brain monoamine oxidase (MAO) inhibitory effects, apoptotic actions in human gastric carcinoma cells and mo...
|
TN4046 |
Excisanin A
|
78536-37-5
|
98%
|
|
ExcisaninA may be a potent inhibitor of AKT signaling pathway in tumor cells, it can inhibit invasion by suppressing MMP-2 and MMP-9 expression, it may be a pote...
|
T12455 |
PI3K/HDAC-IN-1
|
2361418-52-0
|
98%
|
|
PI3K/HDAC-IN-1 is a potent PI3K and HDAC dual inhibitor(IC50s of 8.1 nM and 1.4 nM, respectively).
|
T13311 |
Vps34-IN-2
|
1523404-29-6
|
98%
|
|
Vps34-IN-2 is a potent and selective Vps34 inhibitor (IC50s: 2 and 82 nM on the Vps34 enzymatic assay and the GFP-FYVE cellular assay, respectively).
|
T12465 |
PI3Kγ inhibitor 2
|
1315538-79-4
|
98%
|
|
PI3Kγ inhibitor 2 is an orally bioavailable inhibitor of PI3Kγ(Ki of 4 nM).
|
TN3655 |
Cimiside E
|
154822-57-8
|
98%
|
|
Cimiside E has anti-inflammatory activity, it selectively inhibits TNF-α-induced expression of VCAM-1 at least by upregulation of PPAR-γ, and signals for ERK1/2,...
|
TN3218 |
7-(4-Hydroxyphenyl)-1-phenyl-4-hepten-3-one
|
100667-52-5
|
98%
|
|
7-(4-Hydroxyphenyl)-1-phenyl-4-hepten-3-one as a beneficial compound to ameliorate the deleterious effects of Aβ on dendrite integrity and cell survival, and may...
|
TN3806 |
Dehydroglyasperin C
|
199331-35-6
|
98%
|
|
Dehydroglyasperin C is a potent NAD(P)H:oxidoquinone reductase (NQO1) and phase 2 enzyme inducer. Dehydroglyasperin C possesses potent antioxidant, cancer chemop...
|
T12464 |
PI3Kγ inhibitor 1
|
1172118-03-4
|
98%
|
|
PI3Kγ inhibitor 1 is a inhibitor of PI3Kδ and PI3Kγ.
|
T5166 |
Leniolisib
|
1354690-24-6
|
99.97%
|
|
Leniolisib (CDZ173) (CDZ173) is a potent and selective PI3Kδ inhibitor (IC50: 11 nM).
|
T16422 |
P110δ-IN-1
|
1595129-71-7
|
99.95%
|
|
P110δ-IN-1 (PWT-143) is an effective and selective inhibitor of P110δ (IC50: 8.4 nM).
|
T4079 |
LY-294002 hydrochloride
|
934389-88-5
|
99.95%
|
|
LY-294002 hydrochloride (NSC 697286) is a synthetic molecule inhibitor of PI3Kα/δ/β (IC50: 0.5/0.57/0.97 μM, in cell-free assays); more stable than Wortmannin in...
|
T6087 |
AZD 6482
|
1173900-33-8
|
99.95%
|
|
AZD 6482 (AZD6482) is a potent and selective p110β inhibitor with IC50 of 0.69 nM and a PI3Kβ inhibitor with IC50 of 10 nM.
|