PKA

protein kinase A (PKA) is a family of enzymes whose activity is dependent on cellular levels of cyclic AMP (cAMP). PKA is also known as cAMP-dependent protein kinase . Protein kinase A has several functions in the cell, including regulation of glycogen, sugar, and lipid metabolism.

Cat. No.	Product name	CAS No.	Purity
T3050	ML-7 hydrochloride	110448-33-4	99.61%
T3050	ML-7 hydrochloride (ML-7 HCl) is a cell-permeable, reversible, effective, ATP-competitive, and specific inhibitor of myosin light chain kinase (Ki: 300 nM); also...
T1418	Bucladesine sodium	16980-89-5	99.58%
T1418	Bucladesine sodium (DC2797) is a cAMP analog with cell-permeable properties. Bucladesine sodium is also a cAMP-dependent protein kinase (PKA) activator and a pho...
T6139L	A-674563 2HCl(552325-73-2(fb-2hcl))	T6139L	99.57%
T6139L	A-674563 2HCl is an Akt1 inhibitor with Ki of 11 nM, modest potent to PKA and >30-fold selective for Akt1 over PKC.
T19836	2-Aminopurine	452-06-2	99.51%
T19836	2-Aminopurine is a double-stranded RNA-dependent protein kinase, protein kinase R (PKR) inhibitor.
TP1957L	PKI (5-24) Acetate(99534-03-9 free base)	TP1957L	99.47%
TP1957L	PKI (5-24) Acetate is a high affinity PKA inhibitor (Ki = 2.3 nM).
T0610	Piceatannol	10083-24-6	99.39%
T0610	Piceatannol (Astringenin) is an anti-inflammatory, immunomodulatory and antiproliferative agent. It inhibits p56lck and syk protein tyrosine kinases and inhibits...
T1837	BX-912	702674-56-4	99.34%
T1837	BX-912 is a specific inhibitor of 3-Phosphoinositide-dependent Kinase-1 (PDK1, IC50: 12 nM). The selectivity of BX-912 is more 10 fold than C-Kit, EGFR, PKA, PKC...
T77504	JAK1/2/3 Inhibitor 1	16234-14-3	99.32%
T77504	JAK1/2/3 Inhibitor 1 is a potent protein kinase inhibitor.JAK1/2/3 Inhibitor 1 has antitumor activity that inhibits the growth of a variety of cancer cell lines....
T21674L	PKA inhibitor fragment (6-22) amide Acetate	T21674L	99.30%
T21674L	PKA inhibitor fragment (6-22) amide Acetate is a synthetic peptide which selectively inhibits PKA activity by binding to its substrate site (IC50 < 2 nM).
TP1787L	PKG Substrate acetate（81187-14-6 free base)	TP1787L	99.30%
TP1787L	PKG Substrate acetate is a selective substrate for cGMP-dependent protein kinase (PKG).PKG Substrate is a selective substrate for protein kinase G (PKG) with a s...
T6680	Staurosporine	62996-74-1	99.24%
T6680	Staurosporine (AM-2282) is a protein kinase inhibitor with ATP-competitive and non-selective inhibitory activity (IC50=6/15/2/3/3000 nM) against PKC, PKA, c-Fgr,...
T6139	A-674563	552325-73-2	99.21%
T6139	A-674563 is an Akt1 inhibitor with Ki of 11 nM, modest potent to PKA and >30-fold selective for Akt1 over PKC.
T6303	CCT128930	885499-61-6	99.18%
T6303	CCT128930 is a potent, ATP-competitive and selective inhibitor of Akt2 with IC50 of 6 nM, 28-fold greater selectivity for Akt2 than the closely related PKA kinas...
T6315	MLN8054	869363-13-3	99.05%
T6315	MLN8054 is a potent and selective Aurora A kinase inhibitor with an IC50 of 4 nM.
T27525	HA-1004	91742-10-8	99.03%
T27525	HA-1004 is a inhibitor of PKG, PKA, PKC and MLC.
T2482	AT13148	1056901-62-2	99%
T2482	AT13148 is an oral-active and ATP-competitive, multi-AGC kinase inhibitor for Akt1/2/3, p70S6K, PKA, and ROCKI/II.
T4276L	Hydroxyfasudil	105628-72-6	98.79%
T4276L	Hydroxyfasudil (Hydroxy-Fasudil) is a ROCK inhibitor(IC50s of 0.73 and 0.72 μM for ROCK1 and ROCK2, respectively).
T13807	OSIP-486823	200803-37-8	98.59%
T13807	OSIP-486823（CP248） is a novel and potent microtubule disruptor with affinity for both protein kinase G (PKG) and microtubules.
T6303L	CCT128930 hydrochloride	2453324-32-6	98.55%
T6303L	CCT128930 hydrochloride (CCT128930 hydrochloride) is a potent and selective inhibitor of AKT with IC50 of 6 nM. CCT128930 hydrochloride induces cell cycle arrest...
T3513	GSK180736A	817194-38-0	98.16%
T3513	GSK180736A is an effective and selective GRK2 inhibitor (IC50: 0.77 μM) and >100-fold selectivity over other GRKs. It is a weak inhibitor of PKA (IC50: 30 μM), b...