Cat. No. | Product name | CAS No. | Purity | Chemical Structure |
---|---|---|---|---|
T80544 | PTPσ Inhibitor, ISP | 98% |
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PTPσ Inhibitor ISP is a compound that binds to recombinant human PTPs, thereby inhibiting PTPσ signaling. It has the capability to penetrate membranes and counte... | ||||
T80571 | Eurestobart | 2682847-53-4 | 98% |
Eurestobart
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Eurestobart is a humanized IgG1κ (IgG1 kappa) monoclonal antibody that specifically targets the enzyme ectonucleoside triphosphate diphosphohydrolase (ENTPDase).... | ||||
TN2887 | 3,4-Secocucurbita-4,24-diene-3,26,29-trioic acid | 329975-47-5 | 98% |
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(24E)-3,4-Seco-cucurbita-4,24-diene-3,26,29-trioic acid can inhibit the activity of protein tyrosine phosphatase 1B (PTP1B), with IC 50 values of 0.4uM. | ||||
T3930 | Taraxerol acetate | 2189-80-2 | 98% |
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Taraxeryl acetate shows the significant antiviral activity against herpes simplex virus (type II). It has less effect on cell cycle arrest and apoptosis of AGS c... | ||||
TN3525 | Boehmenan | 57296-22-7 | 98% |
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(±)-Boehmenan shows potent protein-tyrosine phosphatase 1B (PTP1B) inhibitory activity in vitro with the IC(50) values of 43.5 uM, it inhibits PTP1B activity in ... | ||||
T11687 | Itacitinib adipate | 1334302-63-4 | 98% |
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Itacitinib adipate is an orally bioavailable and selective JAK1 inhibitor,Itacitinib adipate has been tested for efficacy and safety in a phase II trial in myelo... | ||||
TN3335 | Abyssinone V | 77263-11-7 | 98% |
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Abyssinone V is a natural compound isolated from the stem bark of Erythrina melanacantha and an inhibitor of protein tyrosine phosphatase-1B (PTP1B). | ||||
T14037 | 3α-Aminocholestane | 2206-20-4 | 98% |
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3α-Aminocholestane (5α-Cholestan-3α-amine) is a potent inhibitor of inositol-5'-phosphatase 1 (SHIP1) containing the SH2 structural domain (IC50 : 2.5 μM) for re... | ||||
T11735 | K-Ras G12C-IN-1 | 1629265-17-3 | 98% |
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K-Ras G12C-IN-1 is a novel and irreversible inhibitor of mutant K-ras G12C. | ||||
T12934 | SMAP-2 | 1809068-70-9 | 98% |
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SMAP-2 is an orally bioavailable activator of phosphatase 2A (PP2A) which binds to the PP2A Aα scaffold subunit to drive conformational changes in PP2A. It inhib... | ||||
TN4551 | Methyl orsellinate | 3187-58-4 | 98% |
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Methyl orsellinate is a phytotoxic compound, it exhibits antifungal activity, it can cause significant inhibition of radicle growth of Amaranthus hypochondriacus... | ||||
T15243 | Ertiprotafib | 251303-04-5 | 98% |
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Ertiprotafib is a PTP1B, IkB kinase β (IKK-β), and a dual PPARα and PPARβ agonist inhibitor ( IC50s: 1.6 μM for PTP1B, 400 nM for IKK-β, an EC50 of ~1 μM for PPA... | ||||
TN4064 | Flavoglaucin | 523-73-9 | 98% |
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Flavoglaucin exhibits significant inhibitory effects on PTP1B, the IC50 value of 13.4, micrometer; it also shows good binding affinity for human opioid or cannab... | ||||
T60396 | JMS-053 | 1954650-11-3 | 98% |
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JMS-053 is a potent and selective inhibitor of the phosphatase DUSP3, inhibits PTP4A3, PTP4A1, PTP4A2 and CDC25B, inhibits cancer cell migration and sphere growt... | ||||
T15166 | DPM-1001 | 1471172-27-6 | 98% |
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DPM-1001 is an orally bioavailable and non-competitive protein-tyrosine phosphatase (PTP1B) inhibitor (IC50: 100 nM) with the anti-diabetic property. | ||||
T16517 | PGMI-004A | 1313738-90-7 | 98% |
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PGMI-004A is an effective inhibitor of phosphoglycerate mutase 1 (IC50: 13.1 μM). | ||||
TN3505 | Beta-Peltoboykinolic acid | 24778-48-1 | 98% |
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Beta-Peltoboykinolic acid has in vitro protein tyrosine phosphatase 1B (PTP1B) inhibitory, it inhibits PTP1B with IC50 values of 5.2+/-0.5 microM. It also has cy... | ||||
T10060L | DT-061 | 1809427-19-7 | 98% |
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DT-061 is an orally bioavailable protein phosphatase 2A (PP2A) activator. It could be applied in the therapy of KRAS-mutant and MYC-driven tumorigenesis. | ||||
TN2913 | 3-Acetoxy-11-ursen-28,13-olide | 35959-08-1 | 98% |
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3β-Acetoxy-urs-11-en-28,13-olide exhibits significant protein tyrosine phosphatase 1B (PTP1B) inhibitory activity, it is a mixed-type PTP1B inhibitor. It exhibit... | ||||
T35806 | N-Stearoylsphingosine | 2304-81-6 | 98% |
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N-Stearoylsphingosine (Cer(d18:1/18:0)) is an amide compound widely found in eukaryotic organisms that enhances protein phosphatase 2A (PP2A) activity by interfe... |