T9205 |
NCGC00378430
|
920650-00-6
|
99.98%
|
|
NCGC00378430 is a potent SIX1/EYA2 interaction inhibitor that disrupts the SIX1/EYA2 complex, EMT, and Metastasis.
|
T3045 |
Salubrinal
|
405060-95-9
|
99.97%
|
|
Salubrinal, a phosphatases (PP1) inhibitor(IC50=1.7 μM), exhibits function on the eukaryotic translation initiation factor 2 subunit (eIF2α).
|
T13013 |
Sodium stibogluconate
|
16037-91-5
|
99.95%
|
|
Sodium stibogluconate (Stibogluconate trisodium nonahydrate) is a potent protein tyrosine phosphatase inhibitor.
|
T10486 |
BCI
|
1245792-51-1
|
99.95%
|
|
BCI ((E)-BCI) is an allosteric inhibitor of dual-specificity phosphatase (DUSP; EC50s: 13.3 and 8.0 μM for DUSP6 and DUSP1 in cells) and does not inhibit DUSP5.
|
T2481 |
Ascomycin
|
104987-12-4
|
99.94%
|
|
Ascomycin (Immunomycin)(Immunomycin, FR-900520, FK520) is an ethyl analog of tacrolimus (FK506) with strong immunosuppressant properties.
|
T77661 |
H-NTPDase-IN-4
|
2939933-09-0
|
99.92%
|
|
h-NTPDase-IN-4 is a pan-inhibitor of NTPDase, which can inhibit h-NTPDase1, 1h-NTPDase2, h-NTPDase3, h-NTPDase8. The IC50 values were 3.58 μM, 10.21 μM, 0.13 μM ...
|
T5708 |
LUPENONE
|
1617-70-5
|
99.92%
|
|
Lupenone is a natural product isolated from Rhizoma Musae and has good anti-diabetic activity,and has anti-inflammatory activity.lupenone were potent PTP1B inhib...
|
T4671 |
BN82002
|
396073-89-5
|
99.91%
|
|
BN82002 (CDC25 Phosphatase Inhibitor I) is a synthetic inhibitor of CDC25 phophatases
|
T12577 |
PTP1B-IN-3
|
809272-64-8
|
99.91%
|
|
PTP1B-IN-3 is a selective and potent PTP1B inhibitor with anticancer activity that inhibits PTP1B and TCPTP.PTP1B-IN-3 is used in the study of diabetes.
|
T8519 |
Raphin1 acetate
|
2242616-04-0
|
99.88%
|
|
Raphin1 acetate is a selective and orally bioavailable regulatory phosphatase PPP1R15B (R15B) inhibitor.
|
T7411 |
Rbin-1
|
328023-11-6
|
99.88%
|
|
Rbin-1 (Ribozinoindole-1) is a potent,specific inhibitor of eukaryotic ribosome biogenesis.
|
T2144 |
Tacrolimus
|
104987-11-3
|
99.87%
|
|
Tacrolimus (Fujimycin) can bind FKBP12 to form a high-affinity complex (Ki: 0.2 nM) which inhibits the activity of the calcium/calmodulin-dependent protein phosp...
|
T17235 |
Voclosporin
|
515814-01-4
|
99.85%
|
|
Voclosporin (ISAtx-247) is a novel and orally available calcium-modulated phosphatase (CN; PP2B) inhibitor and immunosuppressant for the treatment of lupus nephr...
|
T12080 |
MLS000544460
|
352336-36-8
|
99.84%
|
|
MLS000544460 is a highly selective and reversible Eya2 phosphatase inhibitor (Kd: 2.0 μM, IC50: 4 μM).MLS000544460 exhibits inhibitory effects on Eya2 phosphatas...
|
T8573 |
NSC 65809
|
94023-67-3
|
99.84%
|
|
NSC-65809 (Raphin1) is a selective inhibitor of R15B.
|
TN1053 |
Aloe-emodin-8-O-β-D-glucopyranoside
|
33037-46-6
|
99.82%
|
|
Aloe-emodin-8-O-β-D-glucopyranoside (Aloe-emodin-8-O-beta-D-glucopyranoside) shows moderate bioactivity against human Protein Tyrosine Phosphatase 1B (hPTP1B) in...
|
T22215 |
1-Naphthyl phosphate potassium salt
|
100929-85-9
|
99.81%
|
|
1-Naphthyl phosphate potassium salt inhibits non-specific phosphatase.
|
T16773 |
Ro 90-7501
|
293762-45-5
|
99.80%
|
|
Ro 90-7501 is an amyloid β42 (Aβ42) protofibrillar and TPR-dependent PP5 inhibitor, a novel radiosensitiser for cervical cancer cells, which inhibits ATM phospho...
|
T21824 |
Sephin1
|
13098-73-2
|
99.8%
|
|
Sephin1 (IFB-088) is reportedly a selective inhibitor of GADD34 (PPP1R15A), which is a stress-induced regulatory subunit of protein phosphatase 1 complex that de...
|
T3962 |
TPI-1
|
79756-69-7
|
99.79%
|
|
TPI-1 is a SHP-1 inhibitor.
|