T65086 |
Cis-5-Norbornene-exo-2,3-dicarboxylic Anhydride
|
2746-19-2
|
99.32%
|
|
Cis-5-Norbornene-exo-2,3-dicarboxylic Anhydride may cause sensitization. Cis-5-Norbornene-exo-2,3-dicarboxylic Anhydride promotes apoptosis in HepG2 (IC50= 62 μM...
|
T3804 |
Neomangiferin
|
64809-67-2
|
99.32%
|
|
Neomangiferin (Mangiferin 7-glucoside) has beneficial effects on high fat diet-induced nonalcoholic fatty liver disease in rats. Neomangiferin and mangiferin inh...
|
T2P2923 |
Stearic acid
|
57-11-4
|
99.31%
|
|
1. Stearic acid (Cetylacetic acid) can reduce metastatic tumor burden. 2. Stearic acid leads to dramatically reduced visceral fat likely by causing the apoptosis...
|
T6521 |
GSK 2830371
|
1404456-53-6
|
99.3%
|
|
GSK 2830371 is an orally active, allosteric Wip1 phosphatase inhibitor with IC50 of 6 nM.
|
TCS1372 |
Atraric acid
|
4707-47-5
|
99.27%
|
|
Atraric acid derivatives as a new chemical lead structure for novel therapeutic compounds as AR antagonists, that can be used for prophylaxis or treatment of pro...
|
T8478 |
SC-43
|
1400989-25-4
|
99.26%
|
|
SC-43 is a potent and orally active agonist of SHP-1 (PTPN6). SC-43 inhibits the phosphorylation of STAT3 and induces cell apoptosis, and with anti-fibrotic and ...
|
T20879 |
Tacrolimus monohydrate
|
109581-93-3
|
99.2%
|
|
Tacrolimus monohydrate (LCP-Tacro) is a macrolide from the culture broth of a strain of Streptomyces tsukubaensis, binds to FK506 binding protein (FKBP) to form ...
|
T12901 |
SHIP2-IN-1
|
2252247-80-4
|
99.16%
|
|
SHIP2-IN-1 is a potent SHIP2 inhibitor(IC50 : 2 µM),and used in the research of Alzheimer’s disease.
|
T14327 |
AS1949490
|
1203680-76-5
|
99.16%
|
|
AS1949490 activated glucose metabolism via up-regulation of GLUT1 gene in L6 myotubes[1][2]. AS1949490 is a potent and selective SHIP-2 (SH2 domain-containing in...
|
T11955 |
MB-07729
|
882755-95-5
|
99.14%
|
|
MB-07729 is a potent non-competitive inhibitor of fructose-1,6-bisphosphate with IC50 values of 189, 121 and 31 nM in rat, monkey and human, respectively, for th...
|
T81417 |
PP5-IN-1
|
1022417-69-1
|
99.13%
|
|
PP5-IN-1 is a potent and competitive serine/threonine protein phosphatase-5 (PP5) inhibitor with potential anticancer activity that induces apoptosis in cancer c...
|
T9156 |
CDC25B-IN-2
|
134271-74-2
|
99.12%
|
|
BIA is an inhibitor of the interaction between TMBIM6 and mTORC2, which ultimately blocks AKT activation and cancer progression.
|
T4852 |
Trimyristin
|
555-45-3
|
99.11%
|
|
Trimyristin (Tritetradecanoin) is primarily located in the membrane (predicted from logP) and adiposome. glyceryl trimyristate exists in all eukaryotes, ranging ...
|
T22276 |
Bis(maltolato)oxovanadium(IV)
|
38213-69-3
|
99.10%
|
|
Bis(maltolato)oxovanadium(IV) (BMOV) is a potent, reversible, competitive and orally active pan-PTP (protein tyrosine phosphatases)inhibitor with insulin-mimicki...
|
T7084 |
2-Bromo-4'-hydroxyacetophenone
|
2491-38-5
|
99.07%
|
|
2-Bromo-4'-hydroxyacetophenone(PTP Inhibitor I) is a cell-permeable, protein tyrosine phosphatase (PTP) inhibitor that covalently blocks the catalytic domain of ...
|
T61268 |
Vutiglabridin
|
1800188-47-9
|
98.90%
|
|
Vutiglabridin (HSG4112) is a novel and safe modulator of PON2, a racemic compound. vutiglabridin is an optimized structural analogue of Glabridin and is superior...
|
T6353 |
(-)-p-Bromotetramisole Oxalate
|
62284-79-1
|
98.89%
|
|
(-)-p-Bromotetramisole Oxalate (6-Bromolevamisole oxalate) is a potent and non-specific inhibitor of alkaline phosphatase.
|
T9196 |
IACS-13909
|
2160546-07-4
|
98.83%
|
|
IACS-13909 (BBP-398), a specific and potent allosteric inhibitor of SHP2, that suppresses signaling through the MAPK pathway.
|
T16009L |
Managlinat dialanetil
|
280782-97-0
|
98.82%
|
|
Managlinat dialanetil (MB06322) is an orally available and potent fructose 1,6-bisphosphatase (FBPase) inhibitor with hypoglycaemic activity for the study of typ...
|
T28506 |
Rbin-2
|
2032282-97-4
|
98.75%
|
|
Rbin-2 is a cell-permeable, potent, selective and reversible inhibitor of Midasin (Mdn1).Rbin-2 directly targets the AAA+ ATPase Midasin and inhibits eukaryotic ...
|