T3564 |
SHP099
|
1801747-42-1
|
98.73%
|
|
SHP099 (SHP099 free base) free base is an effective, selective, orally bioavailable, and efficacious SHP2 inhibitor (IC50 =0.07 μM and p-ERK modulation in cells ...
|
T14841 |
BVT948
|
39674-97-0
|
98.70%
|
|
BVT948 is a protein tyrosine phosphatase (PTP) inhibitor. It can also inhibit several CYP450 isoforms and lysine methyltransferase SETD8 (KMT5A).
|
T7381 |
TCS 401
|
243966-09-8
|
98.65%
|
|
TCS 401 is a selective inhibitor of protein-tyrosine phosphatase 1B (PTP1B; Ki = 0.29 µM)
|
T4449 |
LB100
|
1632032-53-1
|
98.63%
|
|
LB100 (LB-100) is a water soluble protein phosphatase 2A (PP2A) inhibitor.
|
T7150 |
BTdCPU
|
1257423-87-2
|
98.61%
|
|
BTdCPU is a potent activator of heme-regulated eIF2α kinase (HRI) . BTdCPU promotes eIF2α phosphorylation and induced apoptosis in resistant cell.
|
T0494 |
Tetramisole hydrochloride
|
5086-74-8
|
98.6%
|
|
Tetramisole hydrochloride (Tetramisole HCl) inhibits alkaline phosphatase and is a high-purity antiparasitic agent.
|
T2417 |
Sal003
|
1164470-53-4
|
98.58%
|
|
Sal003, an effective cell-permeable analog, inhibitis the eIF2α phosphatase.
|
T23132 |
Pentamidine dihydrochloride
|
50357-45-4
|
98.58%
|
|
Pentamidine dihydrochloride (MP-601205 dihydrochloride) is an aromatic diamidine agent with activity against a number of microorganisms including protozoa (Trypa...
|
T11139 |
(E/Z)-BCI
|
15982-84-0
|
98.55%
|
|
(E/Z)-BCI (NSC-150117), a dual-specificity phosphatase 6 (DUSP6) inhibitor with anti-inflammatory properties, reduces LPS-induced inflammatory mediators and ROS ...
|
T26684 |
Auten-99 HBr
|
1049780-58-6
|
98.37%
|
|
Auten-99 HBr (Auten-99) is a myotubularin phosphatase Jumpy inhibitor exerting potent neuroprotective effects. AUTEN-99 activates autophagy in cell cultures and ...
|
T6667 |
SF1670
|
345630-40-2
|
98.25%
|
|
SF1670 (PTPase CD45 Inhibitor) is a specific PTEN inhibitor with IC50 of 2 μM.
|
T19389 |
L-Ascorbic acid 2-phosphate magnesium
|
113170-55-1
|
98.23%
|
|
L-Ascorbic acid 2-phosphate magnesium (2-Phospho-L-ascorbic acid magnesium) acts as an antioxidant and a stimulator of hepatocyte growth factor (HGF) production....
|
T11053 |
DJ001
|
2161305-12-8
|
98.21%
|
|
DJ001 is a highly specific, selective and non-competitive protein tyrosine phosphatase σ (PTPσ) inhibitor with IC50 of 1.43 μM. DJ001 promotes the regeneration o...
|
T23133 |
Pentamidine
|
100-33-4
|
98.13%
|
|
Pentamidine is an antifungal and antiprotozoal agent, interacting directly with the pathogen genome by binding to AT-rich regions of duplex DNA and the minor gro...
|
T13410 |
ZLDI-8
|
667880-38-8
|
98.09%
|
|
ZLDI-8 is an inhibitor of Notch activating/cleaving enzyme ADAM-17 and inhibits the cleavage of Notch protein.
|
T67893 |
PTP1B-IN-22
|
86109-60-6
|
98.05%
|
|
PTP1B-IN-22 is a protein tyrosine phosphatase 1B (PTP1B) inhibitor that inhibits glucose uptake in skeletal muscle L6 myotubes.
|
T11929 |
M2N12
|
2376577-06-7
|
98.01%
|
|
M2N12 also has promising activity against Cdc25A and Cdc25B with IC50 values of 0.53 μM and 1.39 μM. Anti-tumor activity. M2N12 is a potent and highly selectiv...
|
T5891 |
D-ERYTHRO-SPHINGOSINE
|
123-78-4
|
98.00%
|
|
D-erythro-Sphingosine (trans-4-Sphingenine) is a protein kinase C (PKC) inhibitor. D-erythro-Sphingosine (Erythrosphingosine) is also a PP2A activator
|
T6911 |
NSC-87877 disodium
|
56932-43-5
|
98%
|
|
NSC-87877 disodium (NSC87877) is a cell-permeable inhibitor of both SHP-1 and SHP-2 with IC50 values of 355 and 318 nM respectively. It also inhibits EGF-induced...
|
T0945 |
Cyclosporin A
|
59865-13-3
|
98%
|
|
Cyclosporin A is a naturally occurring cyclic polypeptide that is the active metabolite of a fungus. Cyclosporin A is an immunosuppressant that binds to procycli...
|