T2434 |
LY 303511
|
154447-38-8
|
99.91%
|
|
LY303511, an inactive analogue of LY294002, is a mTOR inhibitor and no inhibition for PI3-K.
|
TN3910 |
Ecdysone
|
3604-87-3
|
100%
|
|
Ecdysone is a major steroid hormone in insects and herbs. Ecdysone triggers mineralocorticoid receptor activation and induces cellular apoptosis. Ecdysone signal...
|
TN3042 |
4-Hydroxycinnamamide
|
194940-15-3
|
98%
|
|
4-Hydroxycinnamamide has antioxidant activity. 4-Hydroxycinnamamide derivatives are specific inhibitors of tyrosine-specific protein kinases.
|
T78062 |
Dendrotoxin K TFA
|
|
98%
|
|
Dendrotoxin K TFA, a Kv1.1 channel blocker, modulates glutamate release in CA3 neurons by time-dependently regulating the presynaptic spike waveform [1].
|
T78523 |
Clobutinol hydrochloride
|
1215-83-4
|
98%
|
|
Clobutinol hydrochloride, an antitussive agent, influences heart rate and blood pressure, and is utilized in cough-related research [1] [2] [3].
|
T78868 |
TWIK-1/TREK-1-IN-1
|
1440532-30-8
|
98%
|
|
Compound 2a, identified as TWIK-1/TREK-1-IN-1, acts as an inhibitor of the TREK-1, a two-pore domain potassium channel (K2p) that forms TREK-1 homodimers and TWI...
|
T78869 |
TWIK-1/TREK-1-IN-2
|
1440532-32-0
|
98%
|
|
TWIK-1/TREK-1-IN-2 (Compound 2g) serves as an inhibitor of both TWIK-1 and TREK-1, targeting the TREK-1 homodimer and TWIK-1/TREK-1 heterodimer with IC50 values ...
|
T79445 |
KV1.3-IN-1
|
|
98%
|
|
KV1.3-IN-1 (Compound trans-18), a selective KV1.3 channel inhibitor with IC50 values of 230 nM in Ltk cells and 26.12 nM in PHA-activated T-lymphocytes, disrupts...
|
T80028 |
Iberiotoxin TFA
|
|
98%
|
|
Iberiotoxin (TFA) is a selective inhibitor of high conductance Ca2+-activated K+ channels, exhibiting a dissociation constant (Kd) of approximately 1 nM, yet it ...
|
T80034 |
Margatoxin TFA
|
|
98%
|
|
Margatoxin TFA, an alpha-KTx scorpion toxin isolated from Centruroides margaritatus venom, is a 39-amino-acid peptide that serves as a high-affinity inhibitor of...
|
T80036 |
AmmTX3 TFA
|
|
98%
|
|
AmmTX3 TFA, a peptide toxin derived from Androctonus mauretanicus scorpion venom, functions as a selective blocker of the K_v4 channel. It inhibits the A-type K^...
|
T80050 |
Noxiustoxin
|
85205-49-8
|
98%
|
|
Noxiustoxin, a toxin extracted from the venom of the Mexican scorpion Centruroides noxius, inhibits both the voltage-dependent potassium channel (Kv1.3, IC50 = 3...
|
T80053 |
Phrixotoxin-1
|
221872-97-5
|
98%
|
|
Phrixotoxin 1, a specific peptide inhibitor of Kv4 potassium channels, originates from the venom of the theraphosid spider Phrixotrichus auratus [1] [2].
|
T80054 |
Phrixotoxin 2
|
741738-57-8
|
98%
|
|
Phrixotoxin 2 selectively blocks the KV 4.2 and KV 4.3 channels, demonstrating high specificity in its interaction with these voltage-gated ion channels [1].
|
T80058 |
Pandinotoxin Kα
|
185529-64-0
|
98%
|
|
Pandinotoxin Kα, a chemical compound extracted from the emperor scorpion (Pandinus imperator) venom, functions as an inhibitor of the A-type potassium channel [1...
|
T80061 |
Hongotoxin-1
|
|
98%
|
|
Hongotoxin-1, a chemical compound isolated from the venom of Centruroides limbatus, functions as a potassium channel inhibitor. It exhibits inhibitory concentrat...
|
T80064 |
Dendrotoxin-I
|
107950-33-4
|
98%
|
|
Dendrotoxin-I, a neurotoxin from Dendroaspis snake venom, potently blocks K⁺ channels, specifically targeting voltage-gated potassium channel subunits KV1.1 and ...
|
T80066 |
ShK toxin
|
172450-46-3
|
98%
|
|
ShK toxin, isolated from the Caribbean sea anemone (Stichodactyla helianthus), is an inhibitor of the voltage-dependent potassium channel (Kv1.3 channel). It com...
|
T80068 |
Slotoxin
|
|
98%
|
|
Slotoxin, a peptide extracted from the venom of the Centruroides noxius Hoffmann scorpion, inhibits high-conductance calcium-activated potassium channels with a ...
|
T80170 |
Tamapin
|
|
98%
|
|
Tamapin, a venom peptide isolated from the Indian red scorpion (Mesobuthus tamulus) [1], selectively targets and blocks small-conductance Ca(2+)-activated K(+) (...
|