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Potassium Channel

Potassium Channels. K+ channels are membrane proteins that allow rapid and selective flow of K+ ions across the cell membrane, and thus generate electrical signals in cells. Voltage-gated K+ channels (Kv channels), present in all animal cells, open and close upon changes in the transmembrane potential.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T7505 Azimilide Dihydrochloride 149888-94-8 98%
Azimilide Dihydrochloride
Azimilide Dihydrochloride (NE-10064 Dihydrochloride), a novel class III antiarrhythmic agent, blocks both the slowly activating (IKs) and rapidly activating (IKr...
T7612 ICA 110381 325457-99-6 98%
ICA 110381
ICA 110381 is a KCNQ2/Q3 potassium channel opener for the treatment of epilepsy
T0675 Topiramate 97240-79-4 98%
Topiramate
Topiramate (RWJ 17021) is a unique antiseizure medication that is used in the treatment of partial and generalized seizures. Topiramate has been rarely associate...
T7538 Tetraethylammonium chloride 56-34-8 98%
Tetraethylammonium chloride
Tetraethylammonium chloride is a quaternary ammonium compound. It is a non-selective potassium channel blocker. It is a good substrate for organic cation transpo...
T5180 SKA-31 40172-65-4 98%
SKA-31
SKA-31 (Naphtho[1,2-d]thiazol-2-ylamine) is an activator of KCa3.1 and KCa2 channels (EC50s: 260, 2900, 2900 nM for KCa3.1, KCa2.1 and KCa2.2 respectively).
T7512 BMS-191011 202821-81-6 98%
BMS-191011
BMS-191011 (BMS-A) is an activator of large-conductance calcium-activated potassium (BKCa) channels ,effective in stroke models
T7195 GSK369796 Dihydrochloride 1010411-21-8 98%
GSK369796 Dihydrochloride
GSK369796 Dihydrochloride (N-tert-butylisoquine),is an anti-malaria drug candidate. is an affordable and effective antimalarial and inhibits hERG potassium ion c...
T8361 Tetraethylammonium bromide 71-91-0 98%
Tetraethylammonium bromide
Tetraethylammonium bromide (TEA bromide) can selectively block potassium channels.
T1066 Ketanserin 74050-98-9 98%
Ketanserin
Ketanserin (Ketanserinum) is a quinazoline derivative and serotonin (5-hydroxytryptamine, 5HT) receptor subtype 2 (5-HTR2) antagonist with potential antihyperten...
T10623 BSH-IN-1 2553217-91-5 98%
BSH-IN-1
BSH-IN-1 is a potent and covalent inhibitor of gut bacterial recombinant bile salt hydrolases (BSHs; IC50s: 108 nM and 427 nM for B. longum BSH and B. theta BSH)...
T30520 BMS-394136 343246-73-1 97.86%
BMS-394136
BMS-394136 (BMS 394136) is a KV1.5 antagonist for the treatment of cardiovascular diseases such as arrhythmias and atrial fibrillation.
T73267 VU6036720 97.81%
VU6036720
VU6036720 is a potent and selective inhibitor of the isomeric Kir4.1/5.1.VU6036720 inhibits Kir4.1/5.1 activity by decreasing the channel open-circuit probabilit...
T4664 ML 297 1443246-62-5 97.77%
ML 297
ML 297 is a selective Kir3.1/3.2 (GIRK1/2) channel activator (IC50 values are 160, 887 and 914 nM for GIRK1/2, GIRK1/4 and GIRK1/3 respectively). ML 297 exhibits...
T7198 E-4031 113559-13-0 97.71%
E-4031
E-4031 is a methanesulfonanilide class III antiarrhythmic agent that prolongs cardiac action potential duration by blocking ERG K+ channels (IC50 = 29 nM)
T7774 A2793 88349-90-0 97.7%
A2793
A2793 is a dual inhibitor of TWIK-associated acid-sensitive K+ channel 1 (TASK-1)/TRESK, with an IC50 for mTRESK of 6.8 μM. It is more selective for TRESK, and r...
T22745 DPO-1 43077-30-1 97.52%
DPO-1
DPO-1 is a blocker of IKur ultrarapid delayed rectifier potassium current and KV1.5 channels
T4423 LY 303511 hydrochloride 2070014-90-1 97.44%
LY 303511 hydrochloride
LY 303511 hydrochloride is a potent mTOR inhibitor
T9714 Atpenin A5 119509-24-9 97.33%
Atpenin A5
Atpenin A5 is a potent and highly specific complex II inhibitor (IC50 ~10 nM). Atpenin A5 is also an effective mKATP channel agonist and cardioprotective agent[1...
T4294 NS 11021 956014-19-0 97%
NS 11021
NS 11021 (NS11021) , a novel opener of large-conductance Ca(2+)-activated K(+) channels
T12255 NS19504 327062-46-4 95.00%
NS19504
NS19504 is an activator of Ca2+-activated K+ channel with EC50 of 11.0 µM. NS19504 shows relaxing effect on bladder smooth muscle spontaneous phasic contractions...
Azimilide Dihydrochloride
T7505
Azimilide Dihydrochloride (NE-10064 Dihydrochloride), a novel class III antiarrhythmic agent, blocks both the slowly activating (IKs) and rapidly activating (IKr...
ICA 110381
T7612
ICA 110381 is a KCNQ2/Q3 potassium channel opener for the treatment of epilepsy
Topiramate
T0675
Topiramate (RWJ 17021) is a unique antiseizure medication that is used in the treatment of partial and generalized seizures. Topiramate has been rarely associate...
Tetraethylammonium chloride
T7538
Tetraethylammonium chloride is a quaternary ammonium compound. It is a non-selective potassium channel blocker. It is a good substrate for organic cation transpo...
SKA-31
T5180
SKA-31 (Naphtho[1,2-d]thiazol-2-ylamine) is an activator of KCa3.1 and KCa2 channels (EC50s: 260, 2900, 2900 nM for KCa3.1, KCa2.1 and KCa2.2 respectively).
BMS-191011
T7512
BMS-191011 (BMS-A) is an activator of large-conductance calcium-activated potassium (BKCa) channels ,effective in stroke models
GSK369796 Dihydrochloride
T7195
GSK369796 Dihydrochloride (N-tert-butylisoquine),is an anti-malaria drug candidate. is an affordable and effective antimalarial and inhibits hERG potassium ion c...
Tetraethylammonium bromide
T8361
Tetraethylammonium bromide (TEA bromide) can selectively block potassium channels.
Ketanserin
T1066
Ketanserin (Ketanserinum) is a quinazoline derivative and serotonin (5-hydroxytryptamine, 5HT) receptor subtype 2 (5-HTR2) antagonist with potential antihyperten...
BSH-IN-1
T10623
BSH-IN-1 is a potent and covalent inhibitor of gut bacterial recombinant bile salt hydrolases (BSHs; IC50s: 108 nM and 427 nM for B. longum BSH and B. theta BSH)...
BMS-394136
T30520
BMS-394136 (BMS 394136) is a KV1.5 antagonist for the treatment of cardiovascular diseases such as arrhythmias and atrial fibrillation.
VU6036720
T73267
VU6036720 is a potent and selective inhibitor of the isomeric Kir4.1/5.1.VU6036720 inhibits Kir4.1/5.1 activity by decreasing the channel open-circuit probabilit...
ML 297
T4664
ML 297 is a selective Kir3.1/3.2 (GIRK1/2) channel activator (IC50 values are 160, 887 and 914 nM for GIRK1/2, GIRK1/4 and GIRK1/3 respectively). ML 297 exhibits...
E-4031
T7198
E-4031 is a methanesulfonanilide class III antiarrhythmic agent that prolongs cardiac action potential duration by blocking ERG K+ channels (IC50 = 29 nM)
A2793
T7774
A2793 is a dual inhibitor of TWIK-associated acid-sensitive K+ channel 1 (TASK-1)/TRESK, with an IC50 for mTRESK of 6.8 μM. It is more selective for TRESK, and r...
DPO-1
T22745
DPO-1 is a blocker of IKur ultrarapid delayed rectifier potassium current and KV1.5 channels
LY 303511 hydrochloride
T4423
LY 303511 hydrochloride is a potent mTOR inhibitor
Atpenin A5
T9714
Atpenin A5 is a potent and highly specific complex II inhibitor (IC50 ~10 nM). Atpenin A5 is also an effective mKATP channel agonist and cardioprotective agent[1...
NS 11021
T4294
NS 11021 (NS11021) , a novel opener of large-conductance Ca(2+)-activated K(+) channels
NS19504
T12255
NS19504 is an activator of Ca2+-activated K+ channel with EC50 of 11.0 µM. NS19504 shows relaxing effect on bladder smooth muscle spontaneous phasic contractions...
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TargetMol