T7505 |
Azimilide Dihydrochloride
|
149888-94-8
|
98%
|
|
Azimilide Dihydrochloride (NE-10064 Dihydrochloride), a novel class III antiarrhythmic agent, blocks both the slowly activating (IKs) and rapidly activating (IKr...
|
T7612 |
ICA 110381
|
325457-99-6
|
98%
|
|
ICA 110381 is a KCNQ2/Q3 potassium channel opener for the treatment of epilepsy
|
T0675 |
Topiramate
|
97240-79-4
|
98%
|
|
Topiramate (RWJ 17021) is a unique antiseizure medication that is used in the treatment of partial and generalized seizures. Topiramate has been rarely associate...
|
T7538 |
Tetraethylammonium chloride
|
56-34-8
|
98%
|
|
Tetraethylammonium chloride is a quaternary ammonium compound. It is a non-selective potassium channel blocker. It is a good substrate for organic cation transpo...
|
T5180 |
SKA-31
|
40172-65-4
|
98%
|
|
SKA-31 (Naphtho[1,2-d]thiazol-2-ylamine) is an activator of KCa3.1 and KCa2 channels (EC50s: 260, 2900, 2900 nM for KCa3.1, KCa2.1 and KCa2.2 respectively).
|
T7512 |
BMS-191011
|
202821-81-6
|
98%
|
|
BMS-191011 (BMS-A) is an activator of large-conductance calcium-activated potassium (BKCa) channels ,effective in stroke models
|
T7195 |
GSK369796 Dihydrochloride
|
1010411-21-8
|
98%
|
|
GSK369796 Dihydrochloride (N-tert-butylisoquine),is an anti-malaria drug candidate. is an affordable and effective antimalarial and inhibits hERG potassium ion c...
|
T8361 |
Tetraethylammonium bromide
|
71-91-0
|
98%
|
|
Tetraethylammonium bromide (TEA bromide) can selectively block potassium channels.
|
T1066 |
Ketanserin
|
74050-98-9
|
98%
|
|
Ketanserin (Ketanserinum) is a quinazoline derivative and serotonin (5-hydroxytryptamine, 5HT) receptor subtype 2 (5-HTR2) antagonist with potential antihyperten...
|
T10623 |
BSH-IN-1
|
2553217-91-5
|
98%
|
|
BSH-IN-1 is a potent and covalent inhibitor of gut bacterial recombinant bile salt hydrolases (BSHs; IC50s: 108 nM and 427 nM for B. longum BSH and B. theta BSH)...
|
T30520 |
BMS-394136
|
343246-73-1
|
97.86%
|
|
BMS-394136 (BMS 394136) is a KV1.5 antagonist for the treatment of cardiovascular diseases such as arrhythmias and atrial fibrillation.
|
T73267 |
VU6036720
|
|
97.81%
|
|
VU6036720 is a potent and selective inhibitor of the isomeric Kir4.1/5.1.VU6036720 inhibits Kir4.1/5.1 activity by decreasing the channel open-circuit probabilit...
|
T4664 |
ML 297
|
1443246-62-5
|
97.77%
|
|
ML 297 is a selective Kir3.1/3.2 (GIRK1/2) channel activator (IC50 values are 160, 887 and 914 nM for GIRK1/2, GIRK1/4 and GIRK1/3 respectively). ML 297 exhibits...
|
T7198 |
E-4031
|
113559-13-0
|
97.71%
|
|
E-4031 is a methanesulfonanilide class III antiarrhythmic agent that prolongs cardiac action potential duration by blocking ERG K+ channels (IC50 = 29 nM)
|
T7774 |
A2793
|
88349-90-0
|
97.7%
|
|
A2793 is a dual inhibitor of TWIK-associated acid-sensitive K+ channel 1 (TASK-1)/TRESK, with an IC50 for mTRESK of 6.8 μM. It is more selective for TRESK, and r...
|
T22745 |
DPO-1
|
43077-30-1
|
97.52%
|
|
DPO-1 is a blocker of IKur ultrarapid delayed rectifier potassium current and KV1.5 channels
|
T4423 |
LY 303511 hydrochloride
|
2070014-90-1
|
97.44%
|
|
LY 303511 hydrochloride is a potent mTOR inhibitor
|
T9714 |
Atpenin A5
|
119509-24-9
|
97.33%
|
|
Atpenin A5 is a potent and highly specific complex II inhibitor (IC50 ~10 nM). Atpenin A5 is also an effective mKATP channel agonist and cardioprotective agent[1...
|
T4294 |
NS 11021
|
956014-19-0
|
97%
|
|
NS 11021 (NS11021) , a novel opener of large-conductance Ca(2+)-activated K(+) channels
|
T12255 |
NS19504
|
327062-46-4
|
95.00%
|
|
NS19504 is an activator of Ca2+-activated K+ channel with EC50 of 11.0 µM. NS19504 shows relaxing effect on bladder smooth muscle spontaneous phasic contractions...
|