T8372 |
VU0134992
|
755002-90-5
|
98.03%
|
|
VU0134992 is an Kir4.1 blocker with an IC50 value of 0.97 μM
|
T68730 |
AVE1231
|
767334-89-4
|
98.03%
|
|
AVE1231 is a TASK-1 channel blocker that inhibits TASK-1 and can be used in the study of atrial fibrillation.
|
T2712 |
Nifekalant hydrochloride
|
130656-51-8
|
98%
|
|
Nifekalant hydrochloride is an IKr potassium channel blocker with an IC50 of 10 µM. It is a Class III antiarrhythmic compound and can be used in the study of tac...
|
T1752 |
NS6180
|
353262-04-1
|
98%
|
|
NS6180 is a potent and selective KCa3.1 channel inhibitor(IC50= 9 nM). It prevents T-cell activation and inflammation.
|
T7505 |
Azimilide Dihydrochloride
|
149888-94-8
|
98%
|
|
Azimilide Dihydrochloride (NE-10064 Dihydrochloride), a novel class III antiarrhythmic agent, blocks both the slowly activating (IKs) and rapidly activating (IKr...
|
T7612 |
ICA 110381
|
325457-99-6
|
98%
|
|
ICA 110381 is a KCNQ2/Q3 potassium channel opener for the treatment of epilepsy
|
T0675 |
Topiramate
|
97240-79-4
|
98%
|
|
Topiramate (RWJ 17021) is a unique antiseizure medication that is used in the treatment of partial and generalized seizures. Topiramate has been rarely associate...
|
T7538 |
Tetraethylammonium chloride
|
56-34-8
|
98%
|
|
Tetraethylammonium chloride is a quaternary ammonium compound. It is a non-selective potassium channel blocker. It is a good substrate for organic cation transpo...
|
T5180 |
SKA-31
|
40172-65-4
|
98%
|
|
SKA-31 (Naphtho[1,2-d]thiazol-2-ylamine) is an activator of KCa3.1 and KCa2 channels (EC50s: 260, 2900, 2900 nM for KCa3.1, KCa2.1 and KCa2.2 respectively).
|
T7512 |
BMS-191011
|
202821-81-6
|
98%
|
|
BMS-191011 (BMS-A) is an activator of large-conductance calcium-activated potassium (BKCa) channels ,effective in stroke models
|
T0365 |
Thioridazine hydrochloride
|
130-61-0
|
98%
|
|
Thioridazine hydrochloride (Mellaril) , an antipsychotic drug, is used in the therapy of psychosis and schizophrenia and shows serotonin antagonism or D4 selecti...
|
T7195 |
GSK369796 Dihydrochloride
|
1010411-21-8
|
98%
|
|
GSK369796 Dihydrochloride (N-tert-butylisoquine),is an anti-malaria drug candidate. is an affordable and effective antimalarial and inhibits hERG potassium ion c...
|
T8361 |
Tetraethylammonium bromide
|
71-91-0
|
98%
|
|
Tetraethylammonium bromide (TEA bromide) can selectively block potassium channels.
|
T1066 |
Ketanserin
|
74050-98-9
|
98%
|
|
Ketanserin (Ketanserinum) is a quinazoline derivative and serotonin (5-hydroxytryptamine, 5HT) receptor subtype 2 (5-HTR2) antagonist with potential antihyperten...
|
T10623 |
BSH-IN-1
|
2553217-91-5
|
98%
|
|
BSH-IN-1 is a potent and covalent inhibitor of gut bacterial recombinant bile salt hydrolases (BSHs; IC50s: 108 nM and 427 nM for B. longum BSH and B. theta BSH)...
|
T73267 |
VU6036720
|
|
97.81%
|
|
VU6036720 is a potent and selective inhibitor of the isomeric Kir4.1/5.1.VU6036720 inhibits Kir4.1/5.1 activity by decreasing the channel open-circuit probabilit...
|
T4664 |
ML 297
|
1443246-62-5
|
97.77%
|
|
ML 297 is a selective Kir3.1/3.2 (GIRK1/2) channel activator (IC50 values are 160, 887 and 914 nM for GIRK1/2, GIRK1/4 and GIRK1/3 respectively). ML 297 exhibits...
|
T7198 |
E-4031
|
113559-13-0
|
97.71%
|
|
E-4031 is a methanesulfonanilide class III antiarrhythmic agent that prolongs cardiac action potential duration by blocking ERG K+ channels (IC50 = 29 nM)
|
T7774 |
A2793
|
88349-90-0
|
97.7%
|
|
A2793 is a dual inhibitor of TWIK-associated acid-sensitive K+ channel 1 (TASK-1)/TRESK, with an IC50 for mTRESK of 6.8 μM. It is more selective for TRESK, and r...
|
T22745 |
DPO-1
|
43077-30-1
|
97.52%
|
|
DPO-1 is a blocker of IKur ultrarapid delayed rectifier potassium current and KV1.5 channels
|