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Potassium Channel

Potassium Channels. K+ channels are membrane proteins that allow rapid and selective flow of K+ ions across the cell membrane, and thus generate electrical signals in cells. Voltage-gated K+ channels (Kv channels), present in all animal cells, open and close upon changes in the transmembrane potential.

Cat. No.	Product name	CAS No.	Purity
TN1874	Liriodendrin	573-44-4	98%
TN1874	Liriodendrin regulates lung inflammation, the phosphorylation of the NF-kB (p65) and expression of vascular endothelial growth factor (VEGF). Liriodendrin has an...
T12865	SCH-23390 maleate	87134-87-0	98%
T12865	SCH-23390 maleate (R-(+)-SCH-23390 maleate) is a potent and selective antagonist of dopamine D1-like receptor (1 and D5 receptor with Kis of 0.2 nM and 0.3 nM, r...
TN5060	Stauntosaponin A	1417887-91-2	98%
TN5060	Stauntosaponin A and stauntosaponin B show moderate inhibitory activities against Na+/K+-ATPase with IC50 values of 21 and 29 uM, respectively.
TN4638	Neolinine	112515-37-4	98%
TN4638	Neolinine(at 10uM) shows significant hERG K+ channel inhibition activity.
T0801	Tannic acid	1401-55-4	AR
T0801	Tannic acid (Gallotannic acid) is a novel hERG channel blocker.
T26324	VU0071063	333415-38-6	99.99%
T26324	VU0071063 is a Kir6.2/SUR1 activator.
T0127	Glimepiride	93479-97-1	99.97%
T0127	Glimepiride (HOE-490) is a long-acting, third-generation sulfonylurea with hypoglycemic activity.
T0451	Minoxidil	38304-91-5	99.97%
T0451	Minoxidil (U10858) is an orally administered vasodilator with hair growth stimulatory and antihypertensive effects.
T3303	ML277	1401242-74-7	99.97%
T3303	ML277 (CID-53347902) was identified as a potent activator of KCNQ1 channels (EC(50)=260 nM).
T3332	Isosteviol	27975-19-5	99.97%
T3332	Isosteviol ((-)-Isosteviol), a common natural sweetener, belongs to tetracyclic diterpene glycosides. The pharmacology researches have suggested that stevioside ...
T0847	Chenodeoxycholic acid	474-25-9	99.97%
T0847	Chenodeoxycholic acid (CDCA) is a bile acid, usually conjugated with either glycine or taurine. It acts as a detergent to solubilize fats for intestinal absorpti...
T2088	APD668	832714-46-2	99.97%
T2088	APD668 is a potent GPR119 agonist with EC50 of 2.7 nM and 33 nM for hGPR119 and ratGPR119, respectively.
T6978	Almitrine mesylate	29608-49-9	99.96%
T6978	Almitrine mesylate (Almitrine dimesylate) inhibits selectively the Ca2+-dependent K+ channel and that in rat chemoreceptor cells,used in the treatment of hypoxem...
T12478	Pinacidil monohydrate	85371-64-8	99.96%
T12478	Pinacidil monohydrate is a potassium channel activator, antihypertensive drug.
T1260	Cromolyn sodium	15826-37-6	99.95%
T1260	Cromolyn sodium (FPL-670) is a chromone complex that acts by inhibiting the release of chemical mediators from sensitized mast cells.
T13320	VU591 hydrochloride	1315380-70-1	99.95%
T13320	VU591 hydrochloride is a selective renal outer medullary potassium channel (Kir1.1, ROMK) antagonist (IC50：0.24 μM). Thought to block the intracellular pore of t...
T5S0890	Oleandrin	465-16-7	99.94%
T5S0890	1. Oleandrin (Folinerin), the principal cardiac glycoside component of PBI-524, can quantitatively account for regulation of BDNF at both the protein and transcr...
T8135	Minoxidil sulfate	83701-22-8	99.93%
T8135	Minoxidil sulfate (U-58838) is the active metabolite required to exert the vasodilatory and hair growing effects of minoxidil.
T15758	Linopirdine	105431-72-9	99.92%
T15758	Linopirdine (DuP 996) is a TRPV1 agonist. Linopirdine is an orally active and selective M-type K+ current (IM; Kv7; KCNQ Channels) inhibitor (IC50: 2.4 μM). Lino...
T80641	Bupivacaine hydrochloride monohydrate	73360-54-0	99.91%
T80641	Bupivacaine hydrochloride monohydrate is a potent NMDA receptor inhibitor of sodium, L-calcium, and potassium channels.Bupivacaine hydrochloride monohydrate inhi...