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Potassium Channel

Potassium Channels. K+ channels are membrane proteins that allow rapid and selective flow of K+ ions across the cell membrane, and thus generate electrical signals in cells. Voltage-gated K+ channels (Kv channels), present in all animal cells, open and close upon changes in the transmembrane potential.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T4224 ML335 825658-06-8 99.73%
ML335
ML335 is a selective activator of TREK-1 and TREK-2.
T7899 VU0810464 2126040-21-7 99.73%
VU0810464
VU0810464 is a non-ureaG protein-gated inwardly-rectifying potassium channels (GIRK, Kir3) activator.
T3557 GAL-021 1380341-99-0 99.73%
GAL-021
GAL-021 an intravenous BKCa-channel blocker.
T20968 CyPPA 73029-73-9 99.72%
CyPPA
CyPPA, a subtype-selective positive modulator of SK channels, decreased spontaneous firing rate, increased the duration of the apamin-sensitive afterhyperpolariz...
T72066 CHET3 2489231-47-0 99.72%
CHET3
CHET3 is a TASK-3 inhibitor that can be used to study pain.
TQ0139 VU 0240551 893990-34-6 99.72%
VU 0240551
VU 0240551 is a selective antagonist of neuronal K-Cl cotransporter KCC2 inhibitor with an IC50 of 560 nM. VU 0240551 inhibits L-type calcium channels and hERG.
T0847 Chenodeoxycholic acid 474-25-9 99.72%
Chenodeoxycholic acid
Chenodeoxycholic acid (CDCA) is a bile acid, usually conjugated with either glycine or taurine. It acts as a detergent to solubilize fats for intestinal absorpti...
T1650 Chlorzoxazone 95-25-0 99.72%
Chlorzoxazone
Chlorzoxazone (Chlorzoxazon) is a Muscle Relaxant. The physiologic effect of chlorzoxazone is by means of Centrally-mediated Muscle Relaxation.
T0858 Flufenamic acid 530-78-9 99.71%
Flufenamic acid
Flufenamic acid (Arlef) is an anthranilic acid derivative with analgesic, anti-inflammatory, and antipyretic properties. It is used in musculoskeletal and joint ...
T3S0081 Oxypeucedanin 737-52-0 99.71%
Oxypeucedanin
1. Oxypeucedanin ((+-)-Oxypeucedanin) has novel anticancer effect, mediated via induction of G2-M cell cycle arrest and apoptosis in human prostate carcinoma DU1...
T1186 Ifenprodil Tartrate 23210-58-4 99.7%
Ifenprodil Tartrate
Ifenprodil is a selective NMDA receptor (glutamate) antagonist.
T0866 Propafenone 54063-53-5 99.69%
Propafenone
Propafenone (Propafenonum) is only found in individuals that have used or taken this drug. It is an antiarrhythmia agent that is particularly effective in ventri...
T60061 RU-TRAAK-2 1210538-56-9 99.68%
RU-TRAAK-2
RU-TRAAK-2 is a reversible inhibitor of TWIK-related arachidonic acid-stimulated K+ channel with no activity for non-K2P channels including Kv1.2, GIRK2, and Slo...
T14982 Clofilium tosylate 92953-10-1 99.68%
Clofilium tosylate
Clofilium tosylate is a potassium channel blocker. It induces apoptosis of human promyelocytic leukemia (HL-60) cells via Bcl-2-insensitive activation of caspase...
T3S0870 Paederosidic acid methyl ester 122413-01-8 99.67%
Paederosidic acid methyl ester
Paederosidic acid methyl ester has antinociception, is possibly related to the pathway of NO-cGMP-ATP sensitive K(+) channels.
T1088 Repaglinide 135062-02-1 99.66%
Repaglinide
Repaglinide (AG-EE 623ZW) is a benzoic acid derivative that stimulates insulin secretion from the pancreas and is used in the therapy of type 2 diabetes. Repagli...
T3959 ICA-069673 582323-16-8 99.66%
ICA-069673
ICA-069673 is an activator of KCNQ2/Q3 potassium channel (IC50: 0.69 μM).
T8040 Cholesterol myristate 1989-52-2 99.65%
Cholesterol myristate
Cholesterol myristate (Cholesteryl myristate) is a natural steroid present in traditional Chinese medicine. Cholesterol myristate binds to several ion channels s...
T0860 Mefloquine hydrochloride 51773-92-3 99.65%
Mefloquine hydrochloride
Mefloquine hydrochloride (Mefloquin hydrochloride) is a quinoline derivative used for the prevention and therapy of P. falciparum malaria.
T0038 Doxapram hydrochloride hydrate 7081-53-0 99.64%
Doxapram hydrochloride hydrate
Doxapram hydrochloride hydrate (Doxapram HCl) inhibits TASK-1, TASK-3, TASK-1/TASK-3 heterodimeric channel function with EC50 of 410 nM, 37 μM, 9 μM, respectivel...
ML335
T4224
ML335 is a selective activator of TREK-1 and TREK-2.
VU0810464
T7899
VU0810464 is a non-ureaG protein-gated inwardly-rectifying potassium channels (GIRK, Kir3) activator.
GAL-021
T3557
GAL-021 an intravenous BKCa-channel blocker.
CyPPA
T20968
CyPPA, a subtype-selective positive modulator of SK channels, decreased spontaneous firing rate, increased the duration of the apamin-sensitive afterhyperpolariz...
CHET3
T72066
CHET3 is a TASK-3 inhibitor that can be used to study pain.
VU 0240551
TQ0139
VU 0240551 is a selective antagonist of neuronal K-Cl cotransporter KCC2 inhibitor with an IC50 of 560 nM. VU 0240551 inhibits L-type calcium channels and hERG.
Chenodeoxycholic acid
T0847
Chenodeoxycholic acid (CDCA) is a bile acid, usually conjugated with either glycine or taurine. It acts as a detergent to solubilize fats for intestinal absorpti...
Chlorzoxazone
T1650
Chlorzoxazone (Chlorzoxazon) is a Muscle Relaxant. The physiologic effect of chlorzoxazone is by means of Centrally-mediated Muscle Relaxation.
Flufenamic acid
T0858
Flufenamic acid (Arlef) is an anthranilic acid derivative with analgesic, anti-inflammatory, and antipyretic properties. It is used in musculoskeletal and joint ...
Oxypeucedanin
T3S0081
1. Oxypeucedanin ((+-)-Oxypeucedanin) has novel anticancer effect, mediated via induction of G2-M cell cycle arrest and apoptosis in human prostate carcinoma DU1...
Ifenprodil Tartrate
T1186
Ifenprodil is a selective NMDA receptor (glutamate) antagonist.
Propafenone
T0866
Propafenone (Propafenonum) is only found in individuals that have used or taken this drug. It is an antiarrhythmia agent that is particularly effective in ventri...
RU-TRAAK-2
T60061
RU-TRAAK-2 is a reversible inhibitor of TWIK-related arachidonic acid-stimulated K+ channel with no activity for non-K2P channels including Kv1.2, GIRK2, and Slo...
Clofilium tosylate
T14982
Clofilium tosylate is a potassium channel blocker. It induces apoptosis of human promyelocytic leukemia (HL-60) cells via Bcl-2-insensitive activation of caspase...
Paederosidic acid methyl ester
T3S0870
Paederosidic acid methyl ester has antinociception, is possibly related to the pathway of NO-cGMP-ATP sensitive K(+) channels.
Repaglinide
T1088
Repaglinide (AG-EE 623ZW) is a benzoic acid derivative that stimulates insulin secretion from the pancreas and is used in the therapy of type 2 diabetes. Repagli...
ICA-069673
T3959
ICA-069673 is an activator of KCNQ2/Q3 potassium channel (IC50: 0.69 μM).
Cholesterol myristate
T8040
Cholesterol myristate (Cholesteryl myristate) is a natural steroid present in traditional Chinese medicine. Cholesterol myristate binds to several ion channels s...
Mefloquine hydrochloride
T0860
Mefloquine hydrochloride (Mefloquin hydrochloride) is a quinoline derivative used for the prevention and therapy of P. falciparum malaria.
Doxapram hydrochloride hydrate
T0038
Doxapram hydrochloride hydrate (Doxapram HCl) inhibits TASK-1, TASK-3, TASK-1/TASK-3 heterodimeric channel function with EC50 of 410 nM, 37 μM, 9 μM, respectivel...
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TargetMol