T4224 |
ML335
|
825658-06-8
|
99.73%
|
|
ML335 is a selective activator of TREK-1 and TREK-2.
|
T7899 |
VU0810464
|
2126040-21-7
|
99.73%
|
|
VU0810464 is a non-ureaG protein-gated inwardly-rectifying potassium channels (GIRK, Kir3) activator.
|
T3557 |
GAL-021
|
1380341-99-0
|
99.73%
|
|
GAL-021 an intravenous BKCa-channel blocker.
|
T20968 |
CyPPA
|
73029-73-9
|
99.72%
|
|
CyPPA, a subtype-selective positive modulator of SK channels, decreased spontaneous firing rate, increased the duration of the apamin-sensitive afterhyperpolariz...
|
T72066 |
CHET3
|
2489231-47-0
|
99.72%
|
|
CHET3 is a TASK-3 inhibitor that can be used to study pain.
|
TQ0139 |
VU 0240551
|
893990-34-6
|
99.72%
|
|
VU 0240551 is a selective antagonist of neuronal K-Cl cotransporter KCC2 inhibitor with an IC50 of 560 nM. VU 0240551 inhibits L-type calcium channels and hERG.
|
T0847 |
Chenodeoxycholic acid
|
474-25-9
|
99.72%
|
|
Chenodeoxycholic acid (CDCA) is a bile acid, usually conjugated with either glycine or taurine. It acts as a detergent to solubilize fats for intestinal absorpti...
|
T1650 |
Chlorzoxazone
|
95-25-0
|
99.72%
|
|
Chlorzoxazone (Chlorzoxazon) is a Muscle Relaxant. The physiologic effect of chlorzoxazone is by means of Centrally-mediated Muscle Relaxation.
|
T0858 |
Flufenamic acid
|
530-78-9
|
99.71%
|
|
Flufenamic acid (Arlef) is an anthranilic acid derivative with analgesic, anti-inflammatory, and antipyretic properties. It is used in musculoskeletal and joint ...
|
T3S0081 |
Oxypeucedanin
|
737-52-0
|
99.71%
|
|
1. Oxypeucedanin ((+-)-Oxypeucedanin) has novel anticancer effect, mediated via induction of G2-M cell cycle arrest and apoptosis in human prostate carcinoma DU1...
|
T1186 |
Ifenprodil Tartrate
|
23210-58-4
|
99.7%
|
|
Ifenprodil is a selective NMDA receptor (glutamate) antagonist.
|
T0866 |
Propafenone
|
54063-53-5
|
99.69%
|
|
Propafenone (Propafenonum) is only found in individuals that have used or taken this drug. It is an antiarrhythmia agent that is particularly effective in ventri...
|
T60061 |
RU-TRAAK-2
|
1210538-56-9
|
99.68%
|
|
RU-TRAAK-2 is a reversible inhibitor of TWIK-related arachidonic acid-stimulated K+ channel with no activity for non-K2P channels including Kv1.2, GIRK2, and Slo...
|
T14982 |
Clofilium tosylate
|
92953-10-1
|
99.68%
|
|
Clofilium tosylate is a potassium channel blocker. It induces apoptosis of human promyelocytic leukemia (HL-60) cells via Bcl-2-insensitive activation of caspase...
|
T3S0870 |
Paederosidic acid methyl ester
|
122413-01-8
|
99.67%
|
|
Paederosidic acid methyl ester has antinociception, is possibly related to the pathway of NO-cGMP-ATP sensitive K(+) channels.
|
T1088 |
Repaglinide
|
135062-02-1
|
99.66%
|
|
Repaglinide (AG-EE 623ZW) is a benzoic acid derivative that stimulates insulin secretion from the pancreas and is used in the therapy of type 2 diabetes. Repagli...
|
T3959 |
ICA-069673
|
582323-16-8
|
99.66%
|
|
ICA-069673 is an activator of KCNQ2/Q3 potassium channel (IC50: 0.69 μM).
|
T8040 |
Cholesterol myristate
|
1989-52-2
|
99.65%
|
|
Cholesterol myristate (Cholesteryl myristate) is a natural steroid present in traditional Chinese medicine. Cholesterol myristate binds to several ion channels s...
|
T0860 |
Mefloquine hydrochloride
|
51773-92-3
|
99.65%
|
|
Mefloquine hydrochloride (Mefloquin hydrochloride) is a quinoline derivative used for the prevention and therapy of P. falciparum malaria.
|
T0038 |
Doxapram hydrochloride hydrate
|
7081-53-0
|
99.64%
|
|
Doxapram hydrochloride hydrate (Doxapram HCl) inhibits TASK-1, TASK-3, TASK-1/TASK-3 heterodimeric channel function with EC50 of 410 nM, 37 μM, 9 μM, respectivel...
|