T2530 |
Levosimendan
|
141505-33-1
|
99.7%
|
|
Levosimendan (OR1259) is a calcium sensitizer used in the management of acutely decompensated congestive heart failure. It increases the sensitivity of the heart...
|
T1186 |
Ifenprodil Tartrate
|
23210-58-4
|
99.7%
|
|
Ifenprodil is a selective NMDA receptor (glutamate) antagonist.
|
T0866 |
Propafenone
|
54063-53-5
|
99.69%
|
|
Propafenone (Propafenonum) is only found in individuals that have used or taken this drug. It is an antiarrhythmia agent that is particularly effective in ventri...
|
T2546 |
Pimozide
|
2062-78-4
|
99.69%
|
|
Pimozide (R6238) is a diphenylbutylpiperidine derivative and a dopamine antagonist with the antipsychotic property. Pimozide selectively inhibits type 2 dopamine...
|
T60061 |
RU-TRAAK-2
|
1210538-56-9
|
99.68%
|
|
RU-TRAAK-2 is a reversible inhibitor of TWIK-related arachidonic acid-stimulated K+ channel with no activity for non-K2P channels including Kv1.2, GIRK2, and Slo...
|
T61239 |
GAL-021 sulfate
|
1380342-00-6
|
99.68%
|
|
GAL-021 sulfate is a BKCa channel blocker that inhibits the analgesic effects of opioids and is used in the study of respiratory control diseases.
|
T23497 |
UK 78282 hydrochloride
|
136647-02-4
|
99.68%
|
|
UK 78282 hydrochloride, a novel potent and selective Kv1.3 blocker.UK 78282 hydrochloride inhibits Kv1.3 voltage-gated potassium channels and suppresses human T ...
|
T14982 |
Clofilium tosylate
|
92953-10-1
|
99.68%
|
|
Clofilium tosylate is a potassium channel blocker. It induces apoptosis of human promyelocytic leukemia (HL-60) cells via Bcl-2-insensitive activation of caspase...
|
T3S0870 |
Paederosidic acid methyl ester
|
122413-01-8
|
99.67%
|
|
Paederosidic acid methyl ester has antinociception, is possibly related to the pathway of NO-cGMP-ATP sensitive K(+) channels.
|
T1088 |
Repaglinide
|
135062-02-1
|
99.66%
|
|
Repaglinide (AG-EE 623ZW) is a benzoic acid derivative that stimulates insulin secretion from the pancreas and is used in the therapy of type 2 diabetes. Repagli...
|
T3959 |
ICA-069673
|
582323-16-8
|
99.66%
|
|
ICA-069673 is an activator of KCNQ2/Q3 potassium channel (IC50: 0.69 μM).
|
T8040 |
Cholesterol myristate
|
1989-52-2
|
99.65%
|
|
Cholesterol Myristate (Cholesteryl Myristate) is a natural steroid found in traditional Chinese medicine that interacts with various ion channels, including the ...
|
T0860 |
Mefloquine hydrochloride
|
51773-92-3
|
99.65%
|
|
Mefloquine hydrochloride (Mefloquin hydrochloride) is a quinoline derivative used for the prevention and therapy of P. falciparum malaria.
|
T0038 |
Doxapram hydrochloride hydrate
|
7081-53-0
|
99.64%
|
|
Doxapram hydrochloride hydrate (Doxapram HCl) effectively inhibits the function of TASK-1, TASK-3, and TASK-1/TASK-3 heterodimeric channels, displaying EC50 valu...
|
T16348 |
NS5806
|
426834-69-7
|
99.63%
|
|
NS5806 is an effective potassium current activator. NS5806 slows KV4.3 and KV4.2 current decay in channel complexes containing KChIP2. NS5806 enhances KV4.3/KChI...
|
T10435 |
Linaprazan
|
248919-64-4
|
99.63%
|
|
Linaprazan (AZD0865) inhibits gastric H+,K+-ATPase by K+-competitive binding with an IC50 of 1.0 μM.
|
T0916 |
Butamben
|
94-25-7
|
99.61%
|
|
Butamben (Butyl 4-aminobenzoate) is a long-duration local anesthetic used for the treatment of chronic pain.
|
T10674 |
Potassium Channel Activator 1
|
908608-06-0
|
99.60%
|
|
Potassium Channel Activator 1 can be used in studies about the treatment of disorders or conditions wherein the dopaminergic system is disrupted such as mood dis...
|
T0791 |
Reserpine
|
50-55-5
|
99.6%
|
|
Reserpine (Serpalan) is an alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage ves...
|
T7056 |
Dronedarone
|
141626-36-0
|
99.58%
|
|
Dronedarone (SR 33589) is an amiodarone analogue which has an effective and promising treatment for Atrial fibrillation.
|