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Potassium Channel

Potassium Channels. K+ channels are membrane proteins that allow rapid and selective flow of K+ ions across the cell membrane, and thus generate electrical signals in cells. Voltage-gated K+ channels (Kv channels), present in all animal cells, open and close upon changes in the transmembrane potential.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T2530 Levosimendan 141505-33-1 99.7%
Levosimendan
Levosimendan (OR1259) is a calcium sensitizer used in the management of acutely decompensated congestive heart failure. It increases the sensitivity of the heart...
T1186 Ifenprodil Tartrate 23210-58-4 99.7%
Ifenprodil Tartrate
Ifenprodil is a selective NMDA receptor (glutamate) antagonist.
T0866 Propafenone 54063-53-5 99.69%
Propafenone
Propafenone (Propafenonum) is only found in individuals that have used or taken this drug. It is an antiarrhythmia agent that is particularly effective in ventri...
T2546 Pimozide 2062-78-4 99.69%
Pimozide
Pimozide (R6238) is a diphenylbutylpiperidine derivative and a dopamine antagonist with the antipsychotic property. Pimozide selectively inhibits type 2 dopamine...
T60061 RU-TRAAK-2 1210538-56-9 99.68%
RU-TRAAK-2
RU-TRAAK-2 is a reversible inhibitor of TWIK-related arachidonic acid-stimulated K+ channel with no activity for non-K2P channels including Kv1.2, GIRK2, and Slo...
T61239 GAL-021 sulfate 1380342-00-6 99.68%
GAL-021 sulfate
GAL-021 sulfate is a BKCa channel blocker that inhibits the analgesic effects of opioids and is used in the study of respiratory control diseases.
T23497 UK 78282 hydrochloride 136647-02-4 99.68%
UK 78282 hydrochloride
UK 78282 hydrochloride, a novel potent and selective Kv1.3 blocker.UK 78282 hydrochloride inhibits Kv1.3 voltage-gated potassium channels and suppresses human T ...
T14982 Clofilium tosylate 92953-10-1 99.68%
Clofilium tosylate
Clofilium tosylate is a potassium channel blocker. It induces apoptosis of human promyelocytic leukemia (HL-60) cells via Bcl-2-insensitive activation of caspase...
T3S0870 Paederosidic acid methyl ester 122413-01-8 99.67%
Paederosidic acid methyl ester
Paederosidic acid methyl ester has antinociception, is possibly related to the pathway of NO-cGMP-ATP sensitive K(+) channels.
T1088 Repaglinide 135062-02-1 99.66%
Repaglinide
Repaglinide (AG-EE 623ZW) is a benzoic acid derivative that stimulates insulin secretion from the pancreas and is used in the therapy of type 2 diabetes. Repagli...
T3959 ICA-069673 582323-16-8 99.66%
ICA-069673
ICA-069673 is an activator of KCNQ2/Q3 potassium channel (IC50: 0.69 μM).
T8040 Cholesterol myristate 1989-52-2 99.65%
Cholesterol myristate
Cholesterol Myristate (Cholesteryl Myristate) is a natural steroid found in traditional Chinese medicine that interacts with various ion channels, including the ...
T0860 Mefloquine hydrochloride 51773-92-3 99.65%
Mefloquine hydrochloride
Mefloquine hydrochloride (Mefloquin hydrochloride) is a quinoline derivative used for the prevention and therapy of P. falciparum malaria.
T0038 Doxapram hydrochloride hydrate 7081-53-0 99.64%
Doxapram hydrochloride hydrate
Doxapram hydrochloride hydrate (Doxapram HCl) effectively inhibits the function of TASK-1, TASK-3, and TASK-1/TASK-3 heterodimeric channels, displaying EC50 valu...
T16348 NS5806 426834-69-7 99.63%
NS5806
NS5806 is an effective potassium current activator. NS5806 slows KV4.3 and KV4.2 current decay in channel complexes containing KChIP2. NS5806 enhances KV4.3/KChI...
T10435 Linaprazan 248919-64-4 99.63%
Linaprazan
Linaprazan (AZD0865) inhibits gastric H+,K+-ATPase by K+-competitive binding with an IC50 of 1.0 μM.
T0916 Butamben 94-25-7 99.61%
Butamben
Butamben (Butyl 4-aminobenzoate) is a long-duration local anesthetic used for the treatment of chronic pain.
T10674 Potassium Channel Activator 1 908608-06-0 99.60%
Potassium Channel Activator 1
Potassium Channel Activator 1 can be used in studies about the treatment of disorders or conditions wherein the dopaminergic system is disrupted such as mood dis...
T0791 Reserpine 50-55-5 99.6%
Reserpine
Reserpine (Serpalan) is an alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage ves...
T7056 Dronedarone 141626-36-0 99.58%
Dronedarone
Dronedarone (SR 33589) is an amiodarone analogue which has an effective and promising treatment for Atrial fibrillation.
Levosimendan
T2530
Levosimendan (OR1259) is a calcium sensitizer used in the management of acutely decompensated congestive heart failure. It increases the sensitivity of the heart...
Ifenprodil Tartrate
T1186
Ifenprodil is a selective NMDA receptor (glutamate) antagonist.
Propafenone
T0866
Propafenone (Propafenonum) is only found in individuals that have used or taken this drug. It is an antiarrhythmia agent that is particularly effective in ventri...
Pimozide
T2546
Pimozide (R6238) is a diphenylbutylpiperidine derivative and a dopamine antagonist with the antipsychotic property. Pimozide selectively inhibits type 2 dopamine...
RU-TRAAK-2
T60061
RU-TRAAK-2 is a reversible inhibitor of TWIK-related arachidonic acid-stimulated K+ channel with no activity for non-K2P channels including Kv1.2, GIRK2, and Slo...
GAL-021 sulfate
T61239
GAL-021 sulfate is a BKCa channel blocker that inhibits the analgesic effects of opioids and is used in the study of respiratory control diseases.
UK 78282 hydrochloride
T23497
UK 78282 hydrochloride, a novel potent and selective Kv1.3 blocker.UK 78282 hydrochloride inhibits Kv1.3 voltage-gated potassium channels and suppresses human T ...
Clofilium tosylate
T14982
Clofilium tosylate is a potassium channel blocker. It induces apoptosis of human promyelocytic leukemia (HL-60) cells via Bcl-2-insensitive activation of caspase...
Paederosidic acid methyl ester
T3S0870
Paederosidic acid methyl ester has antinociception, is possibly related to the pathway of NO-cGMP-ATP sensitive K(+) channels.
Repaglinide
T1088
Repaglinide (AG-EE 623ZW) is a benzoic acid derivative that stimulates insulin secretion from the pancreas and is used in the therapy of type 2 diabetes. Repagli...
ICA-069673
T3959
ICA-069673 is an activator of KCNQ2/Q3 potassium channel (IC50: 0.69 μM).
Cholesterol myristate
T8040
Cholesterol Myristate (Cholesteryl Myristate) is a natural steroid found in traditional Chinese medicine that interacts with various ion channels, including the ...
Mefloquine hydrochloride
T0860
Mefloquine hydrochloride (Mefloquin hydrochloride) is a quinoline derivative used for the prevention and therapy of P. falciparum malaria.
Doxapram hydrochloride hydrate
T0038
Doxapram hydrochloride hydrate (Doxapram HCl) effectively inhibits the function of TASK-1, TASK-3, and TASK-1/TASK-3 heterodimeric channels, displaying EC50 valu...
NS5806
T16348
NS5806 is an effective potassium current activator. NS5806 slows KV4.3 and KV4.2 current decay in channel complexes containing KChIP2. NS5806 enhances KV4.3/KChI...
Linaprazan
T10435
Linaprazan (AZD0865) inhibits gastric H+,K+-ATPase by K+-competitive binding with an IC50 of 1.0 μM.
Butamben
T0916
Butamben (Butyl 4-aminobenzoate) is a long-duration local anesthetic used for the treatment of chronic pain.
Potassium Channel Activator 1
T10674
Potassium Channel Activator 1 can be used in studies about the treatment of disorders or conditions wherein the dopaminergic system is disrupted such as mood dis...
Reserpine
T0791
Reserpine (Serpalan) is an alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage ves...
Dronedarone
T7056
Dronedarone (SR 33589) is an amiodarone analogue which has an effective and promising treatment for Atrial fibrillation.
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TargetMol