Potassium Channel

Potassium Channels. K+ channels are membrane proteins that allow rapid and selective flow of K+ ions across the cell membrane, and thus generate electrical signals in cells. Voltage-gated K+ channels (Kv channels), present in all animal cells, open and close upon changes in the transmembrane potential.

Cat. No.	Product name	CAS No.	Purity
T0386	Ropivacaine hydrochloride	98717-15-8	99.55%
T0386	Ropivacaine hydrochloride (Ropivacaine monohydrochloride) is the hydrochloride salt of ropivacaine, a local anesthetic of the amide type with analgesic activity....
T0438	Proflavine Hemisulfate	1811-28-5	99.55%
T0438	Proflavine Hemisulfate (3,6-Diaminoacridine hemisulfate) is the hemisulfate salt form of proflavine, an acridine-derived fluorescent contrast and disinfectant ag...
T3581	KS176	1253452-78-6	99.55%
T3581	KS176 is a potent and selective inhibitor of the breast cancer resistance protein (BCRP) multidrug transporter, showing no inhibitory activity against P-gp or MR...
T16345	NS13001	1063331-94-1	99.55%
T16345	NS13001 (N-(4-Chlorophenyl)-2-(3,5-dimethyl-1H-pyrazol-1-yl)-9-methyl-9H-purin-6-amine) is a potent, selective, orally active allosteric positive modulator of SK...
T9522	Rimtuzalcap	2167246-24-2	99.54%
T9522	Rimtuzalcap (CAD-1883) (CAD-1883), a pioneering selective positive allosteric modulator of small-conductance calcium-activated potassium channels (SK channels), ...
T3092	Nigericin sodium salt	28643-80-3	99.52%
T3092	Nigericin sodium salt is an antibiotic, an NLRP3 activator, and a cationic ion carrier. Nigericin sodium triggers the activation of the NALP3 inflammasome, which...
T78570	XE991	122955-42-4	99.51%
T78570	XE991 is a novel and selective Kv7 (KCNQ) channel blocker.XE 991 dihydrochloride inhibits Kv7.1 (KCNQ1), Kv7.2 (KCNQ2), Kv7.2 + Kv7.3 (KCNQ3) channels, and M-cur...
T23471	TRAM 39	197525-99-8	99.51%
T23471	TRAM 39 (2-Chloro-α,α-diphenylbenzeneacetonitrile) is a selective blocker of intermediate-conductance Ca2+-activated K+channels.
T1291	Cisapride	81098-60-4	99.5%
T1291	Cisapride (R 51619) is a serotonin type 4 (5-HT4) receptor agonists are potent prokinetic agents that act on serotonin receptors in the intestine and promote int...
T3528	Senicapoc	289656-45-7	99.5%
T3528	Senicapoc (ICA-17043) is a potent inhibitor of the Gardos channel and ameliorates RBC dehydration in the SAD mouse. Senicapoc blocked Ca2+-induced rubidium flux ...
T1496	Amiodarone hydrochloride	19774-82-4	99.49%
T1496	Amiodarone hydrochloride (Amiodarone HCl) is an antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action ...
TQ0179	PAP-1	870653-45-5	99.49%
TQ0179	PAP-1 (5-(4-Phenoxybutoxy)psoralen) is a selective, and orally active Kv1.3 blocker (EC50: 2 nM).
T3S1873	Talatisamine	20501-56-8	99.44%
T3S1873	1. Talatisamine (12 μM) and TEA (5mM) inhibits the enhanced I(K) caused by Aβ4 oligomers, attenuates cytotoxicity of Aβ oligomers by restoring cell viability and...
T1138	Taurocholic acid sodium salt hydrate	345909-26-4	99.43%
T1138	Taurocholic acid sodium salt hydrate (Sodium taurocholate hydrate) is the product of conjugation of taurine with cholic acid. The sodium salt, the main ingredien...
T5183	AUT1	1311136-84-1	99.43%
T5183	AUT1 (AUT-1) is a novel specific modulator of Kv3 channels (EC50: 4.7 and 4.9 uM for Kv3.1b and Kv3.2a).
T3A2467	Allocryptopine	485-91-6	99.41%
T3A2467	Allocryptopine (Thalictrimine) induces muscle contraction and relaxation in urinary bladder and ileum, respectively.
T3574	Sematilide hydrochloride	101526-62-9	99.41%
T3574	Sematilide hydrochloride (CK-1752) is a class III antiarrhythmic. It is a selectively delayed rectifier K+ current (IKr) channel blocker. It inhibits rapidly act...
TP1858L	Phe-Met-Arg-Phe, amide acetate	TP1858L	99.4%
TP1858L	Phe-Met-Arg-Phe, amide acetate dose dependently (ED50=23 nM) activates a K+ current in the peptidergic caudodorsal neurons. This peptide appears to localize with...
T4641	Branaplam	1562338-42-4	99.4%
T4641	Branaplam (LMI 070) is a highly potent, selective and orally active small molecule SMN2 splicing modulator.
T1266	Terfenadine	50679-08-8	99.36%
T1266	Terfenadine ((±)-Terfenadine) is a prodrug that is metabolized by intestinal CYP3A4 to the active form fexofenadine, a selective histamine H1-receptor antagonist...