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Reactive Oxygen Species

Reactive oxygen species (ROS), such as superoxide anion (O2-), hydrogen peroxide (H2O2), and hydroxyl radical (HO•), consist of radical and non-radical oxygen species formed by the partial reduction of oxygen. Cellular ROS are generated endogenously during mitochondrial oxidative metabolism as well as in cellular response to xenobiotics, cytokines, and bacterial invasion. ROS also activates MAPK pathways by the direct inhibition of MAPK phosphatases. Through PTEN, the PI3K pathway is subject to reversible redox regulation by ROS generated by growth factor stimulation. The activation of autophagy may be a cellular defense mechanism in response to ROS.
Cat. No. Product name CAS No. Purity Chemical Structure
T1716 Echinacoside 82854-37-3 98%
Echinacoside is a natural polyphenolic compound with various kinds of pharmacological activities, such as anti-inflammatory, antioxidative, hepatoprotective, neu...
T2818 Methyl Vanillate 3943-74-6 98%
Methyl vanillate is Hovenia Dulcis Thunb extract and its ingredient methyl vanillate activate Wnt/β-catenin pathway and increase bone mass in growing or ovariect...
T2185 L-Ascorbic acid 2-phosphate trisodium 66170-10-3 98%
L-Ascorbic acid 2-phosphate (AA2P) is used in biocatalytic dephosphorylation for electric power generation and electrochemical detection assays.
TN4782 Picein 530-14-3 98%
Picein is derived from Picrorhiza kurroa and shows antioxidant properties.
T0492 Dimethyl fumarate 624-49-7 98%
Dimethyl fumarate, a fumarate derivative, is used as antiinflammatory and immunomodulatory agent.
T8693 Diallyl Trisulfide 2050-87-5 98%
Diallyl Trisulfide is an organic polysulfide compound found in garlic that acts as an H2S donor.
T6460 Cysteamine hydrochloride 156-57-0 98%
Cysteamine is an agent for the treatment of nephropathic cystinosis and an antioxidant.
T1080 2-Aminoethanethiol 60-23-1 98%
Cysteamine is a Cystine Depleting Agent. The mechanism of action of cysteamine is as a Cystine Disulfide Reduction.
T5645 Nerol 106-25-2 98%
Nerol is a monoterpene found in many essential oils, such as lemon balm and hop.Nerol can lessened the severity of ouabain-triggered arrhythmias in mammalian hea...
T0756 Ethoxyquin 91-53-2 98%
Ethoxyquin is an antioxidant used in animal feeds.
T6699 Tempol 2226-96-2 98%
Tempol is a superoxide scavenger. It has anti-inflammatory, neuroprotective and analgesic effects.
T1035 Hesperidin 520-26-3 98%
Hesperidin is a flavanone glycoside found in citrus fruits with antioxidant, anti-inflammatory, anti-carcinogenic, and antihypertensive and lipid-lowering activi...
T5852 Canthaxanthin 514-78-3 98%
Canthaxanthin is a red-orange carotenoid that belongs to the xanthophyll group. This naturally occurring pigment is present in bacteria, algae and some fungi.
T8370 GSK5182 877387-37-6 98%
GSK5182 is a highly selective inverse estrogen-related receptor γ agonist (IC50 : 79 nM)
T2587 Ecabet Sodium 86408-72-2 98%
Ecabet sodium: a potential new agent in the management of distal colitis.
T8320 J14 1043854-13-2 98%
J-14 is an inhibitor of reversible sulfiredoxin(IC50 : 8.1 μM). J14 induces oxidative stress (intracellular ROS accumulation) by inhibiting sulfiredoxin, leading...
T7781 Reynoutrin 549-32-6 98%
Reynoutrin with antioxidant and radical-scavenging activity.
T7191 Diphenyleneiodonium chloride 4673-26-1 98%
Diphenyleneiodonium chloride(DPI) is an irreversible inhibitor of iNOS and eNOS (IC50 values of 50 nM and 0.3 µM, respectively),and displays broad-spectrum bacte...
T6475 (±)-Carnitine chloride 461-05-2 98%
DL-Carnitine HCl is a quaternary ammonium compound biosynthesized from the amino acids lysine and methionine.
T5966 Hexaconazole 79983-71-4 98%
Hexaconazole is a broad-spectrum triazole fungicide that inhibits ergosterol biosynthesis via inhibition of the cytochrome P450-dependent 14α-demethylation of la...
Echinacoside
T1716
Echinacoside is a natural polyphenolic compound with various kinds of pharmacological activities, such as anti-inflammatory, antioxidative, hepatoprotective, neu...
Methyl Vanillate
T2818
Methyl vanillate is Hovenia Dulcis Thunb extract and its ingredient methyl vanillate activate Wnt/β-catenin pathway and increase bone mass in growing or ovariect...
L-Ascorbic acid 2-phosphate trisodium
T2185
L-Ascorbic acid 2-phosphate (AA2P) is used in biocatalytic dephosphorylation for electric power generation and electrochemical detection assays.
Picein
TN4782
Picein is derived from Picrorhiza kurroa and shows antioxidant properties.
Dimethyl fumarate
T0492
Dimethyl fumarate, a fumarate derivative, is used as antiinflammatory and immunomodulatory agent.
Diallyl Trisulfide
T8693
Diallyl Trisulfide is an organic polysulfide compound found in garlic that acts as an H2S donor.
Cysteamine hydrochloride
T6460
Cysteamine is an agent for the treatment of nephropathic cystinosis and an antioxidant.
2-Aminoethanethiol
T1080
Cysteamine is a Cystine Depleting Agent. The mechanism of action of cysteamine is as a Cystine Disulfide Reduction.
Nerol
T5645
Nerol is a monoterpene found in many essential oils, such as lemon balm and hop.Nerol can lessened the severity of ouabain-triggered arrhythmias in mammalian hea...
Ethoxyquin
T0756
Ethoxyquin is an antioxidant used in animal feeds.
Tempol
T6699
Tempol is a superoxide scavenger. It has anti-inflammatory, neuroprotective and analgesic effects.
Hesperidin
T1035
Hesperidin is a flavanone glycoside found in citrus fruits with antioxidant, anti-inflammatory, anti-carcinogenic, and antihypertensive and lipid-lowering activi...
Canthaxanthin
T5852
Canthaxanthin is a red-orange carotenoid that belongs to the xanthophyll group. This naturally occurring pigment is present in bacteria, algae and some fungi.
GSK5182
T8370
GSK5182 is a highly selective inverse estrogen-related receptor γ agonist (IC50 : 79 nM)
Ecabet Sodium
T2587
Ecabet sodium: a potential new agent in the management of distal colitis.
J14
T8320
J-14 is an inhibitor of reversible sulfiredoxin(IC50 : 8.1 μM). J14 induces oxidative stress (intracellular ROS accumulation) by inhibiting sulfiredoxin, leading...
Reynoutrin
T7781
Reynoutrin with antioxidant and radical-scavenging activity.
Diphenyleneiodonium chloride
T7191
Diphenyleneiodonium chloride(DPI) is an irreversible inhibitor of iNOS and eNOS (IC50 values of 50 nM and 0.3 µM, respectively),and displays broad-spectrum bacte...
(±)-Carnitine chloride
T6475
DL-Carnitine HCl is a quaternary ammonium compound biosynthesized from the amino acids lysine and methionine.
Hexaconazole
T5966
Hexaconazole is a broad-spectrum triazole fungicide that inhibits ergosterol biosynthesis via inhibition of the cytochrome P450-dependent 14α-demethylation of la...
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