Reactive Oxygen Species

Reactive oxygen species (ROS), such as superoxide anion (O2-), hydrogen peroxide (H2O2), and hydroxyl radical (HO•), consist of radical and non-radical oxygen species formed by the partial reduction of oxygen. Cellular ROS are generated endogenously during mitochondrial oxidative metabolism as well as in cellular response to xenobiotics, cytokines, and bacterial invasion. ROS also activates MAPK pathways by the direct inhibition of MAPK phosphatases. Through PTEN, the PI3K pathway is subject to reversible redox regulation by ROS generated by growth factor stimulation. The activation of autophagy may be a cellular defense mechanism in response to ROS.

Cat. No.	Product name	CAS No.	Purity
T1716	Echinacoside	82854-37-3	98%
T1716	Echinacoside is a natural polyphenolic compound with various kinds of pharmacological activities, such as anti-inflammatory, antioxidative, hepatoprotective, neu...
T2818	Methyl Vanillate	3943-74-6	98%
T2818	Methyl vanillate is Hovenia Dulcis Thunb extract and its ingredient methyl vanillate activate Wnt/β-catenin pathway and increase bone mass in growing or ovariect...
T2185	L-Ascorbic acid 2-phosphate trisodium	66170-10-3	98%
T2185	L-Ascorbic acid 2-phosphate (AA2P) is used in biocatalytic dephosphorylation for electric power generation and electrochemical detection assays.
TN4782	Picein	530-14-3	98%
TN4782	Picein is derived from Picrorhiza kurroa and shows antioxidant properties.
T0492	Dimethyl fumarate	624-49-7	98%
T0492	Dimethyl fumarate, a fumarate derivative, is used as antiinflammatory and immunomodulatory agent.
T8693	Diallyl Trisulfide	2050-87-5	98%
T8693	Diallyl Trisulfide is an organic polysulfide compound found in garlic that acts as an H2S donor.
T6460	Cysteamine hydrochloride	156-57-0	98%
T6460	Cysteamine is an agent for the treatment of nephropathic cystinosis and an antioxidant.
T1080	2-Aminoethanethiol	60-23-1	98%
T1080	Cysteamine is a Cystine Depleting Agent. The mechanism of action of cysteamine is as a Cystine Disulfide Reduction.
T5645	Nerol	106-25-2	98%
T5645	Nerol is a monoterpene found in many essential oils, such as lemon balm and hop.Nerol can lessened the severity of ouabain-triggered arrhythmias in mammalian hea...
T0756	Ethoxyquin	91-53-2	98%
T0756	Ethoxyquin is an antioxidant used in animal feeds.
T6699	Tempol	2226-96-2	98%
T6699	Tempol is a superoxide scavenger. It has anti-inflammatory, neuroprotective and analgesic effects.
T1035	Hesperidin	520-26-3	98%
T1035	Hesperidin is a flavanone glycoside found in citrus fruits with antioxidant, anti-inflammatory, anti-carcinogenic, and antihypertensive and lipid-lowering activi...
T5852	Canthaxanthin	514-78-3	98%
T5852	Canthaxanthin is a red-orange carotenoid that belongs to the xanthophyll group. This naturally occurring pigment is present in bacteria, algae and some fungi.
T8370	GSK5182	877387-37-6	98%
T8370	GSK5182 is a highly selective inverse estrogen-related receptor γ agonist (IC50 : 79 nM)
T2587	Ecabet Sodium	86408-72-2	98%
T2587	Ecabet sodium: a potential new agent in the management of distal colitis.
T8320	J14	1043854-13-2	98%
T8320	J-14 is an inhibitor of reversible sulfiredoxin(IC50 : 8.1 μM). J14 induces oxidative stress (intracellular ROS accumulation) by inhibiting sulfiredoxin, leading...
T7781	Reynoutrin	549-32-6	98%
T7781	Reynoutrin with antioxidant and radical-scavenging activity.
T7191	Diphenyleneiodonium chloride	4673-26-1	98%
T7191	Diphenyleneiodonium chloride(DPI) is an irreversible inhibitor of iNOS and eNOS (IC50 values of 50 nM and 0.3 µM, respectively),and displays broad-spectrum bacte...
T6475	(±)-Carnitine chloride	461-05-2	98%
T6475	DL-Carnitine HCl is a quaternary ammonium compound biosynthesized from the amino acids lysine and methionine.
T5966	Hexaconazole	79983-71-4	98%
T5966	Hexaconazole is a broad-spectrum triazole fungicide that inhibits ergosterol biosynthesis via inhibition of the cytochrome P450-dependent 14α-demethylation of la...