Reactive Oxygen Species

Reactive oxygen species (ROS), such as superoxide anion (O2-), hydrogen peroxide (H2O2), and hydroxyl radical (HO•), consist of radical and non-radical oxygen species formed by the partial reduction of oxygen. Cellular ROS are generated endogenously during mitochondrial oxidative metabolism as well as in cellular response to xenobiotics, cytokines, and bacterial invasion. ROS also activates MAPK pathways by the direct inhibition of MAPK phosphatases. Through PTEN, the PI3K pathway is subject to reversible redox regulation by ROS generated by growth factor stimulation. The activation of autophagy may be a cellular defense mechanism in response to ROS.

Cat. No.	Product name	CAS No.	Purity
T41242	Uric acid sodium	1198-77-2	99.92%
T41242	Uric acid sodium, scavengers of oxygen radicals, is a potent and common antioxidant that helps maintain stable blood pressure and resist oxidative stress. Uric a...
T6947	Piperlongumine	20069-09-4	99.89%
T6947	Piperlongumine (Piplartine) is a natural alkaloid from Piper longum L. It selectively kills cancer cells and strengthens the level of reactive oxygen species (RO...
T0928	L-Ascorbic acid	50-81-7	99.89%
T0928	L-Ascorbic acid (Vitamin C) is a natural product that is a potent reducing agent and antioxidant. L-Ascorbic acid functions in fighting bacterial infections, in ...
T1648	α-Vitamin E	59-02-9	99.89%
T1648	α-Vitamin E (Dexrabeprazole Sodium) is a naturally-occurring form of vitamin E, a fat-soluble vitamin with potent antioxidant properties.
T33701	NM-3	181427-78-1	99.89%
T33701	NM-3 is an orally available anti-angiogenic inhibitor with anti-tumour activity.NM-3 is used as a radiation modulator in vitro and in vivo.NM-3 inhibits vascular...
T2796	Coenzyme Q10	303-98-0	99.88%
T2796	Coenzyme Q10 (CoQ10) (ubiquinone) is a naturally occurring compound, acting as the electron carrier in the mitochondrial respiratory chain.
T1085L	Glutathione oxidized	27025-41-8	99.88%
T1085L	Glutathione oxidized (L(-)-Glutathione) is a GLUTATHIONE dimer formed by a disulfide bond between the cysteine sulfhydryl side chains during the course of being...
T40795	BNTA	685119-25-9	99.87%
T40795	BNTA is a potent extracellular matrix (ECM) modulator. In a rat model of arthritis, BNTA modulates arthritis by promoting the synthesis of cartilage structural m...
T3604	Sodium dichloroacetate	2156-56-1	99.87%
T3604	Sodium dichloroacetate (BCA) , a specific inhibitor of pyruvate dehydrogenase kinase (PDK) with IC50 values of 183 and 80 μM for PDK2 and PDK4 respectively, has ...
T1439	Lacidipine	103890-78-4	99.85%
T1439	Lacidipine (SN-305) is a lipophilic dihydropyridine calcium antagonist with an intrinsically slow onset of activity. Due to its long duration of action, lacidipi...
T10668	Camalexin	135531-86-1	99.84%
T10668	Camalexin is a phytoalexin isolated from Camelina sativa. It has antifungal, antibacterial, antiproliferative, and anticancer activities. Camalexin can induce RO...
T2817	Picroside II	39012-20-9	99.83%
T2817	Picroside II (Vanilloyl catalpol) is the main active ingredient in iridoid glycosides. It has antioxidant, anti-inflammatory, immune regulatory, anti-virus and o...
T3785	11-oxo-mogroside V	126105-11-1	99.82%
T3785	11-oxo-mogroside V (11-oxo Mogroside V) is a sweet tasting cucurbitane glycoside derivative of mogroside V. It has antioxidant effects against both O2- and OH- a...
T37739	N-decanoyl-L-Homoserine lactone	177315-87-6	99.81%
T37739	N-decanoyl-L-Homoserine lactone (C10-HSL) is an N-acyl-homoserine lactone (AHL) produced by Pseudomonas cremoris strain ND07.N-decanoyl-L-homoserine lactone inhi...
T8377	Mesotrione	104206-82-8	99.81%
T8377	Mesotrione is a selective triketone herbicide
T63918	α-Tocopherol phosphate disodium	60934-46-5	99.81%
T63918	α-Tocopherol phosphate (alpha-Tocopherol phosphate) is an antioxidant that scavenges UVA1-induced reactive oxygen species (ROS) and protects against long-wave UV...
T0461	Berberine chloride	633-65-8	99.8%
T0461	Berberine chloride (Natural Yellow 18) is an alkaloid from Hydrastis canadensis L., Berberidaceae and also found in many other plants. It is relatively toxic to ...
T2767	Neohesperidin Dihydrochalcone	20702-77-6	99.8%
T2767	Neohesperidin Dihydrochalcone (Neohesperidin DC) is an artificial sweetener derived from citrus.
T1710	Trolox	53188-07-1	99.8%
T1710	Trolox is a vitamin E analogue, used in reducing oxidative stress or damage.
T4S0295	Apigenin 7-glucoside	578-74-5	99.79%
T4S0295	1. Apigenin 7-glucoside (Cosmosiin) is a anti-HIV agent. 2. Cosmosiin may be beneficial for diabetic complications through their enhanced adiponectin secretion, ...