Reactive Oxygen Species

Reactive oxygen species (ROS), such as superoxide anion (O2-), hydrogen peroxide (H2O2), and hydroxyl radical (HO•), consist of radical and non-radical oxygen species formed by the partial reduction of oxygen. Cellular ROS are generated endogenously during mitochondrial oxidative metabolism as well as in cellular response to xenobiotics, cytokines, and bacterial invasion. ROS also activates MAPK pathways by the direct inhibition of MAPK phosphatases. Through PTEN, the PI3K pathway is subject to reversible redox regulation by ROS generated by growth factor stimulation. The activation of autophagy may be a cellular defense mechanism in response to ROS.

Cat. No.	Product name	CAS No.	Purity
T0860	Mefloquine hydrochloride	51773-92-3	99.65%
T0860	Mefloquine hydrochloride (Mefloquin hydrochloride) is a quinoline derivative used for the prevention and therapy of P. falciparum malaria.
T38155	N-Acetyl-D-cysteine	26117-28-2	99.63%
T38155	N-Acetyl-D-cysteine has antioxidant activities and scavenges ROS through the reaction with its thiol group.
T10492	BD-AcAc 2	1208313-97-6	99.62%
T10492	BD-AcAc 2 (Ketone Ester) is a ketone monoester and can be used as a source of oral nutritional ketones. BD-AcAc 2 can elevate plasma levels of acetoacetate and β...
T27064	CP-312	895470-67-4	99.61%
T27064	CP-312 (Cardioprotectant 312) is an antioxidant defense response activator that protects hiPSC-CM viability by acting through induction of heme oxygenase-1 and t...
T5728	OsMundacetone	37079-84-8	99.59%
T5728	OsMundacetone (4-(3,4-Dihydroxyphenyl)-3-buten-2-one) is a natual product isolated from Rhizoma osmundae.
T36735	3,5-Di-tert-butylphenol	1138-52-9	99.59%
T36735	3,5-Di-tert-butylphenol induces accumulation of reactive oxygen species. 3,5-Di-tert-butylphenol exhibits anti-biofilm and antifungal activities.
T0891	Dapsone	80-08-0	99.58%
T0891	Dapsone (Sulphadione) has activity against a wide range of bacteria but mainly employed for its actions against mycobacterium leprae.
T0498	Salsalate	552-94-3	99.57%
T0498	Salsalate (Sasapyrine) is an orally available salicylate and non-steroidal anti-inflammatory drug (NSAID), with anti-inflammatory, analgesic and antipyretic acti...
T38423	CL097	1026249-18-2	99.57%
T38423	CL097 is an effective agonist of TLR7 and TLR8. CL097 induces pro-inflammatory cytokines in macrophages and NADPH oxidase priming, thereby increasing the fMLF-st...
T23911	CPS-11	145945-21-7	99.55%
T23911	CPS-11 (N-(Hydroxymethyl)thalidomide) is a Thalidomide analogue that has significant antitumor activity and exhibits a wider range of activity and highly potent ...
T1684	Nitisinone	104206-65-7	99.54%
T1684	Nitisinone (SC0735)(SC0735) is an enzyme 4-hydroxyphenylpyruvate dioxygenase inhibitor.
T3S1692	Octahydrocurcumin	36062-07-4	99.54%
T3S1692	Octahydrocurcumin has antioxidant and and anti-inflammatory activities, it can inhibit the lipopolysaccharide (LPS)-induced inflammatory response via the mechani...
T3429	Protopine	130-86-9	99.54%
T3429	Protopine (Fumarine) is a benzylisoquinoline alkaloid. It has been found to inhibit histamine H1 receptors and platelet aggregation, and acts as an analgesic.
T5098	Isochlorogenic acid A	2450-53-5	99.53%
T5098	Isochlorogenic acid A (3,5-Dicaffeoylquinic acid), a natural phenolic acid, exhibits antioxidant and anti-inflammatory properties.
T0626	Uric Acid	69-93-2	99.52%
T0626	Uric Acid (Lithic acid) is an oxidation product of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans...
T0163	Nisoldipine	63675-72-9	99.51%
T0163	Nisoldipine (BAY-k 5552) is a dihydropyridine calcium channel antagonist that acts as a potent arterial vasodilator and antihypertensive agent.
T2185	L-Ascorbic acid 2-phosphate trisodium	66170-10-3	99.5%
T2185	L-Ascorbic acid 2-phosphate trisodium (Sodium ascorbyl phosphate) is used in biocatalytic dephosphorylation for electric power generation and electrochemical det...
T2S1865	Octyl gallate	1034-01-1	99.5%
T2S1865	1. Octyl Gallate is an antioxidant approved by the US Food and Drug Administration (FDA) as a food additive. 2. Octyl Gallate has antimetastatic activity. 3. Oct...
T2792	Glucosamine sulfate	29031-19-4	99.49%
T2792	Glucosamine sulfate (D-Glucosaminesulfate) was extracted from synthetic product;Store the product in sealed, cool and dry condition.
T6S1529	Cynarin	30964-13-7	99.48%
T6S1529	Cynarin (1,5-Dicaffeoylquinic acid) has neuroprotective, and antioxidant effects, it can inhibition of GSK3β as well as the modulation of Bcl-2/Bax.