Reactive Oxygen Species

Reactive oxygen species (ROS), such as superoxide anion (O2-), hydrogen peroxide (H2O2), and hydroxyl radical (HO•), consist of radical and non-radical oxygen species formed by the partial reduction of oxygen. Cellular ROS are generated endogenously during mitochondrial oxidative metabolism as well as in cellular response to xenobiotics, cytokines, and bacterial invasion. ROS also activates MAPK pathways by the direct inhibition of MAPK phosphatases. Through PTEN, the PI3K pathway is subject to reversible redox regulation by ROS generated by growth factor stimulation. The activation of autophagy may be a cellular defense mechanism in response to ROS.

Cat. No.	Product name	CAS No.	Purity
T7094	Levomefolic Acid	31690-09-2	98%
T7094	Levomefolinic acid is a natural, active form of folic acid used at the cellular level for DNA reproduction, the cysteine cycle and the regulation of homocysteine...
T6482	Efaproxiral Sodium	170787-99-2	98%
T6482	Efaproxiral Sodium , a synthetic allosteric modifier of hemoglobin, is utilized for brain metastases originating from breast cancer.
TN6706	3-demethylcolchicine	7336-33-6	98%
TN6706	3-demethylcolchicine is a natural product isolated from Gloriosa superba.Inhibitory effect on the polymerization of purified bovine brain tubulin.
T2988	(-)-Epigallocatechin Gallate	989-51-5	98%
T2988	Epigallocatechol Gallate(EGCG) is an antioxidant polyphenol flavonoid that inhibits telomerase and DNA methyltransferase. EGCG blocks the activation of EGF recep...
T5518	N-acetylcysteine amide	38520-57-9	98%
T5518	N-Acetylcysteine amide is a cell membranes and blood brain barrier permeant thiol antioxidant and neuroprotective agent
T15458	H2DCFDA	4091-99-0	98%
T15458	H2DCFDA is a cell-permeable probe. Which is used to detect intracellular reactive oxygen species (ROS).
T1717	Alpha-Mangostin	6147-11-1	98%
T1717	Mangostin is a natural xanthonoid, a type of organic compound isolated from various parts of the mangosteen tree.
T2792	Glucosamine sulfate	29031-19-4	98%
T2792	Extracted from synthetic product;Store the product in sealed, cool and dry condition
T2S1865	Octyl gallate	1034-01-1	98%
T2S1865	1. Octyl Gallate is an antioxidant approved by the US Food and Drug Administration (FDA) as a food additive. 2. Octyl Gallate has antimetastatic activity. 3. Oct...
T6170	Elesclomol	488832-69-5	98%
T6170	Elesclomol (STA-4783) is an effective oxidative stress inducer that elicits pro-apoptosis of tumor cells.
T0626	Uric Acid	69-93-2	98%
T0626	Uric acid is an oxidation product of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates,...
T6S2038	Ziyuglycoside II	35286-59-0	98%
T6S2038	1. Ziyuglycoside II has anti-inflammation and antioxidation properties. 2. Ziyuglycoside II has antibiosis, and homeostasis properties. 3. Ziyuglycoside II has a...
T5098	Isochlorogenic acid A	2450-53-5	98%
T5098	3,5-Dicaffeoylquinic acid is a natural phenolic acid with antioxidant and anti-inflammatory activities .
T3429	Protopine	130-86-9	98%
T3429	Protopine is a benzylisoquinoline alkaloid. It has been found to inhibit histamine H1 receptors and platelet aggregation, and acts as an analgesic.
T3S1692	Octahydrocurcumin	36062-07-4	98%
T3S1692	Octahydrocurcumin has antioxidant and and anti-inflammatory activities, it can inhibit the lipopolysaccharide (LPS)-induced inflammatory response via the mechani...
T1684	Nitisinone	104206-65-7	98%
T1684	Nitisinone(SC0735) is an enzyme 4-hydroxyphenylpyruvate dioxygenase inhibitor.
T3240	Citronellol	106-22-9	98%
T3240	Citronellol is used in insect repellents and perfumes and as a mite attractant.
T38423	CL097	1026249-18-2	98%
T38423	CL097 is an effective agonist of TLR7 and TLR8. CL097 induces pro-inflammatory cytokines in macrophages and NADPH oxidase priming, thereby increasing the fMLF-st...
T0163	Nisoldipine	63675-72-9	98%
T0163	Nisoldipine is a dihydropyridine calcium channel antagonist that acts as a potent arterial vasodilator and antihypertensive agent.
T0498	Salsalate	552-94-3	98%
T0498	Salsalate is an orally available salicylate and non-steroidal anti-inflammatory drug (NSAID), with anti-inflammatory, analgesic and antipyretic activities.