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Reactive Oxygen Species

Reactive oxygen species (ROS), such as superoxide anion (O2-), hydrogen peroxide (H2O2), and hydroxyl radical (HO•), consist of radical and non-radical oxygen species formed by the partial reduction of oxygen. Cellular ROS are generated endogenously during mitochondrial oxidative metabolism as well as in cellular response to xenobiotics, cytokines, and bacterial invasion. ROS also activates MAPK pathways by the direct inhibition of MAPK phosphatases. Through PTEN, the PI3K pathway is subject to reversible redox regulation by ROS generated by growth factor stimulation. The activation of autophagy may be a cellular defense mechanism in response to ROS.
Cat. No. Product name CAS No. Purity Chemical Structure
T7094 Levomefolic Acid 31690-09-2 98%
Levomefolinic acid is a natural, active form of folic acid used at the cellular level for DNA reproduction, the cysteine cycle and the regulation of homocysteine...
T6482 Efaproxiral Sodium 170787-99-2 98%
Efaproxiral Sodium , a synthetic allosteric modifier of hemoglobin, is utilized for brain metastases originating from breast cancer.
TN6706 3-demethylcolchicine 7336-33-6 98%
3-demethylcolchicine is a natural product isolated from Gloriosa superba.Inhibitory effect on the polymerization of purified bovine brain tubulin.
T2988 (-)-Epigallocatechin Gallate 989-51-5 98%
Epigallocatechol Gallate(EGCG) is an antioxidant polyphenol flavonoid that inhibits telomerase and DNA methyltransferase. EGCG blocks the activation of EGF recep...
T5518 N-acetylcysteine amide 38520-57-9 98%
N-Acetylcysteine amide is a cell membranes and blood brain barrier permeant thiol antioxidant and neuroprotective agent
T15458 H2DCFDA 4091-99-0 98%
H2DCFDA is a cell-permeable probe. Which is used to detect intracellular reactive oxygen species (ROS).
T1717 Alpha-Mangostin 6147-11-1 98%
Mangostin is a natural xanthonoid, a type of organic compound isolated from various parts of the mangosteen tree.
T2792 Glucosamine sulfate 29031-19-4 98%
Extracted from synthetic product;Store the product in sealed, cool and dry condition
T2S1865 Octyl gallate 1034-01-1 98%
1. Octyl Gallate is an antioxidant approved by the US Food and Drug Administration (FDA) as a food additive. 2. Octyl Gallate has antimetastatic activity. 3. Oct...
T6170 Elesclomol 488832-69-5 98%
Elesclomol (STA-4783) is an effective oxidative stress inducer that elicits pro-apoptosis of tumor cells.
T0626 Uric Acid 69-93-2 98%
Uric acid is an oxidation product of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates,...
T6S2038 Ziyuglycoside II 35286-59-0 98%
1. Ziyuglycoside II has anti-inflammation and antioxidation properties. 2. Ziyuglycoside II has antibiosis, and homeostasis properties. 3. Ziyuglycoside II has a...
T5098 Isochlorogenic acid A 2450-53-5 98%
3,5-Dicaffeoylquinic acid is a natural phenolic acid with antioxidant and anti-inflammatory activities .
T3429 Protopine 130-86-9 98%
Protopine is a benzylisoquinoline alkaloid. It has been found to inhibit histamine H1 receptors and platelet aggregation, and acts as an analgesic.
T3S1692 Octahydrocurcumin 36062-07-4 98%
Octahydrocurcumin has antioxidant and and anti-inflammatory activities, it can inhibit the lipopolysaccharide (LPS)-induced inflammatory response via the mechani...
T1684 Nitisinone 104206-65-7 98%
Nitisinone(SC0735) is an enzyme 4-hydroxyphenylpyruvate dioxygenase inhibitor.
T3240 Citronellol 106-22-9 98%
Citronellol is used in insect repellents and perfumes and as a mite attractant.
T38423 CL097 1026249-18-2 98%
CL097 is an effective agonist of TLR7 and TLR8. CL097 induces pro-inflammatory cytokines in macrophages and NADPH oxidase priming, thereby increasing the fMLF-st...
T0163 Nisoldipine 63675-72-9 98%
Nisoldipine is a dihydropyridine calcium channel antagonist that acts as a potent arterial vasodilator and antihypertensive agent.
T0498 Salsalate 552-94-3 98%
Salsalate is an orally available salicylate and non-steroidal anti-inflammatory drug (NSAID), with anti-inflammatory, analgesic and antipyretic activities.
Levomefolic Acid
T7094
Levomefolinic acid is a natural, active form of folic acid used at the cellular level for DNA reproduction, the cysteine cycle and the regulation of homocysteine...
Efaproxiral Sodium
T6482
Efaproxiral Sodium , a synthetic allosteric modifier of hemoglobin, is utilized for brain metastases originating from breast cancer.
3-demethylcolchicine
TN6706
3-demethylcolchicine is a natural product isolated from Gloriosa superba.Inhibitory effect on the polymerization of purified bovine brain tubulin.
(-)-Epigallocatechin Gallate
T2988
Epigallocatechol Gallate(EGCG) is an antioxidant polyphenol flavonoid that inhibits telomerase and DNA methyltransferase. EGCG blocks the activation of EGF recep...
N-acetylcysteine amide
T5518
N-Acetylcysteine amide is a cell membranes and blood brain barrier permeant thiol antioxidant and neuroprotective agent
H2DCFDA
T15458
H2DCFDA is a cell-permeable probe. Which is used to detect intracellular reactive oxygen species (ROS).
alpha-Mangostin
T1717
Mangostin is a natural xanthonoid, a type of organic compound isolated from various parts of the mangosteen tree.
Glucosamine sulfate
T2792
Extracted from synthetic product;Store the product in sealed, cool and dry condition
Octyl gallate
T2S1865
1. Octyl Gallate is an antioxidant approved by the US Food and Drug Administration (FDA) as a food additive. 2. Octyl Gallate has antimetastatic activity. 3. Oct...
Elesclomol
T6170
Elesclomol (STA-4783) is an effective oxidative stress inducer that elicits pro-apoptosis of tumor cells.
Uric Acid
T0626
Uric acid is an oxidation product of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates,...
Ziyuglycoside II
T6S2038
1. Ziyuglycoside II has anti-inflammation and antioxidation properties. 2. Ziyuglycoside II has antibiosis, and homeostasis properties. 3. Ziyuglycoside II has a...
Isochlorogenic acid A
T5098
3,5-Dicaffeoylquinic acid is a natural phenolic acid with antioxidant and anti-inflammatory activities .
Protopine
T3429
Protopine is a benzylisoquinoline alkaloid. It has been found to inhibit histamine H1 receptors and platelet aggregation, and acts as an analgesic.
Octahydrocurcumin
T3S1692
Octahydrocurcumin has antioxidant and and anti-inflammatory activities, it can inhibit the lipopolysaccharide (LPS)-induced inflammatory response via the mechani...
Nitisinone
T1684
Nitisinone(SC0735) is an enzyme 4-hydroxyphenylpyruvate dioxygenase inhibitor.
Citronellol
T3240
Citronellol is used in insect repellents and perfumes and as a mite attractant.
CL097
T38423
CL097 is an effective agonist of TLR7 and TLR8. CL097 induces pro-inflammatory cytokines in macrophages and NADPH oxidase priming, thereby increasing the fMLF-st...
Nisoldipine
T0163
Nisoldipine is a dihydropyridine calcium channel antagonist that acts as a potent arterial vasodilator and antihypertensive agent.
Salsalate
T0498
Salsalate is an orally available salicylate and non-steroidal anti-inflammatory drug (NSAID), with anti-inflammatory, analgesic and antipyretic activities.
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