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Reductase

Reductase is an enzyme that catalyzes a reduction reaction.
Cat. No. Product name CAS No. Purity Chemical Structure
T16910 Sorbinil 68367-52-2 98%
Sorbinil is an Aldose reductase inhibitor. Sorbinil plays a therapeutic role in treating diabetes and diabetic complications decreases AR activity and inhibit th...
T15281 Fidarestat 136087-85-9 98%
Fidarestat is an aldose reductase inhibitor (IC50s: 26 nM, 33 μM, and 1.8 μM for aldose reductase, AKR1B10, and V301L AKR1B10, respectively). It has the potentia...
TN3760 Danshenol A 189308-08-5 98%
Danshenol A has strong aldose reductase (AR) inhibitory activity, has IC50 of 0.10 microM which is comparable to that of epalrestat in clinical use. Danshenol A ...
TN3287 8-Lavandulylkaempferol 883859-83-4 98%
8-Lavandulylkaempferol exhibits significant inhibitory effects with IC(50) values of 7.10 and 8.11 microM for butyrylcholinesterase and acetylcholinesterase, res...
TN2295 Vicenin-1 35927-38-9 98%
Vicenin-1 possesses potent anti-inflammatory and anti-oxidant activity.
TN1661 Ganoderic acid C2 103773-62-2 98%
Ganoderic acid C2 has anti-inflammatory,and anti-tumor-promoting activities. Ganoderic acid C2 can inhibit histamine release, it also has inhibitory effects on t...
T23403 Sulindac sulfone 59864-04-9 98%
Sulindac sulfone is a metabolite of the nonsteroidal anti-inflammatory drug sulindac.
T35317 Zopolrestat 110703-94-1 98%
Zopolrestat is an aldose reductase inhibitor that may be used in the treatment of diabetic nephropathy and diabetes.
T14175 Aldose reductase-IN-1 1355612-71-3
Aldose reductase-IN-1 is a aldose reductase inhibitor (IC50: 28.9 pM).
T17114 Tolrestat 82964-04-3 100%
Tolrestat is a potent inhibitor of aldose reductase (IC50 = 35 nM).
T3378 Alpha-Estradiol 57-91-0 100%
Endogenous estrogen receptor ligand (Ki values are 0.2 and 1.2 nM for ERα and ERβ receptors respectively).
T6102 2'-acetylacteoside 94492-24-7 97.38%
2'-Acetylacteoside has antioxidative activity. It can significantly attenuate glutamate-induced neurotoxicity at concentrations ranging from 0.1 to 10 μM. 2'-Ace...
T5S0543 Isocurcumenol 24063-71-6 98%
1. Isocurcumenol inhibits 5α-reductase which converts testosterone to dihydrotestosterone (DHT).
T7478 2-Chloro-1-(4-fluorobenzyl)benzimidazole 84946-20-3 98%
2-Chloro-1-(4-fluorobenzyl)benzimidazole is an inhibitor of aldose reductase (ALR2).
T3665 Tectoridin 611-40-5 99.02%
Tectoridin possesses an estrogenic and thyroid hormone-like agent by activating estrogen and thyroid hormone receptors. Tectoridin has anti-oxidant, anti-inflamm...
T0488 Finasteride 98319-26-7 99.04%
Finasteride is an oral inhibitor of active testosterone 5-alpha-reductase and Ki value is 10 nM.
T15568 Imirestat 89391-50-4 99.08%
Imirestat is an aldose reductase inhibitor. It is used for the treatment of diabetes.
T1458 Epalrestat 82159-09-9 99.2%
Epalrestat, an aldose reductase inhibitor, is well tolerated in Long-term therapy. It can effectually ameliorate the associated symptoms of diabetic neuropathy a...
TN2601 12-O-Methylcarnosic acid 62201-71-2 99.24%
12-O-Methylcarnosic acid is a diterpene carnosic acid isolated from the acetone extract of Salvia microphylla, is an active constituent of 5α-reductase inhibitio...
T10393 AT-007 2170729-29-8 99.36%
AT-007 is an orally active CNS penetrant Aldose Reductase inhibitor for the treatment of Galactosemia (IC50: 100 pM). It reduces toxic galactitol levels and prev...
Sorbinil
T16910
Sorbinil is an Aldose reductase inhibitor. Sorbinil plays a therapeutic role in treating diabetes and diabetic complications decreases AR activity and inhibit th...
Fidarestat
T15281
Fidarestat is an aldose reductase inhibitor (IC50s: 26 nM, 33 μM, and 1.8 μM for aldose reductase, AKR1B10, and V301L AKR1B10, respectively). It has the potentia...
Danshenol A
TN3760
Danshenol A has strong aldose reductase (AR) inhibitory activity, has IC50 of 0.10 microM which is comparable to that of epalrestat in clinical use. Danshenol A ...
8-Lavandulylkaempferol
TN3287
8-Lavandulylkaempferol exhibits significant inhibitory effects with IC(50) values of 7.10 and 8.11 microM for butyrylcholinesterase and acetylcholinesterase, res...
Vicenin-1
TN2295
Vicenin-1 possesses potent anti-inflammatory and anti-oxidant activity.
Ganoderic acid C2
TN1661
Ganoderic acid C2 has anti-inflammatory,and anti-tumor-promoting activities. Ganoderic acid C2 can inhibit histamine release, it also has inhibitory effects on t...
Sulindac sulfone
T23403
Sulindac sulfone is a metabolite of the nonsteroidal anti-inflammatory drug sulindac.
Zopolrestat
T35317
Zopolrestat is an aldose reductase inhibitor that may be used in the treatment of diabetic nephropathy and diabetes.
Aldose reductase-IN-1
T14175
Aldose reductase-IN-1 is a aldose reductase inhibitor (IC50: 28.9 pM).
Tolrestat
T17114
Tolrestat is a potent inhibitor of aldose reductase (IC50 = 35 nM).
Alpha-Estradiol
T3378
Endogenous estrogen receptor ligand (Ki values are 0.2 and 1.2 nM for ERα and ERβ receptors respectively).
2'-acetylacteoside
T6102
2'-Acetylacteoside has antioxidative activity. It can significantly attenuate glutamate-induced neurotoxicity at concentrations ranging from 0.1 to 10 μM. 2'-Ace...
Isocurcumenol
T5S0543
1. Isocurcumenol inhibits 5α-reductase which converts testosterone to dihydrotestosterone (DHT).
2-Chloro-1-(4-fluorobenzyl)benzimidazole
T7478
2-Chloro-1-(4-fluorobenzyl)benzimidazole is an inhibitor of aldose reductase (ALR2).
Tectoridin
T3665
Tectoridin possesses an estrogenic and thyroid hormone-like agent by activating estrogen and thyroid hormone receptors. Tectoridin has anti-oxidant, anti-inflamm...
Finasteride
T0488
Finasteride is an oral inhibitor of active testosterone 5-alpha-reductase and Ki value is 10 nM.
Imirestat
T15568
Imirestat is an aldose reductase inhibitor. It is used for the treatment of diabetes.
Epalrestat
T1458
Epalrestat, an aldose reductase inhibitor, is well tolerated in Long-term therapy. It can effectually ameliorate the associated symptoms of diabetic neuropathy a...
12-O-Methylcarnosic acid
TN2601
12-O-Methylcarnosic acid is a diterpene carnosic acid isolated from the acetone extract of Salvia microphylla, is an active constituent of 5α-reductase inhibitio...
AT-007
T10393
AT-007 is an orally active CNS penetrant Aldose Reductase inhibitor for the treatment of Galactosemia (IC50: 100 pM). It reduces toxic galactitol levels and prev...
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