T16910 |
Sorbinil
|
68367-52-2
|
98%
|
|
Sorbinil is an Aldose reductase inhibitor. Sorbinil plays a therapeutic role in treating diabetes and diabetic complications decreases AR activity and inhibit th...
|
T15281 |
Fidarestat
|
136087-85-9
|
98%
|
|
Fidarestat is an aldose reductase inhibitor (IC50s: 26 nM, 33 μM, and 1.8 μM for aldose reductase, AKR1B10, and V301L AKR1B10, respectively). It has the potentia...
|
TN3760 |
Danshenol A
|
189308-08-5
|
98%
|
|
Danshenol A has strong aldose reductase (AR) inhibitory activity, has IC50 of 0.10 microM which is comparable to that of epalrestat in clinical use. Danshenol A ...
|
TN3287 |
8-Lavandulylkaempferol
|
883859-83-4
|
98%
|
|
8-Lavandulylkaempferol exhibits significant inhibitory effects with IC(50) values of 7.10 and 8.11 microM for butyrylcholinesterase and acetylcholinesterase, res...
|
TN2295 |
Vicenin-1
|
35927-38-9
|
98%
|
|
Vicenin-1 possesses potent anti-inflammatory and anti-oxidant activity.
|
TN1661 |
Ganoderic acid C2
|
103773-62-2
|
98%
|
|
Ganoderic acid C2 has anti-inflammatory,and anti-tumor-promoting activities. Ganoderic acid C2 can inhibit histamine release, it also has inhibitory effects on t...
|
T23403 |
Sulindac sulfone
|
59864-04-9
|
98%
|
|
Sulindac sulfone is a metabolite of the nonsteroidal anti-inflammatory drug sulindac.
|
T35317 |
Zopolrestat
|
110703-94-1
|
98%
|
|
Zopolrestat is an aldose reductase inhibitor that may be used in the treatment of diabetic nephropathy and diabetes.
|
T14175 |
Aldose reductase-IN-1
|
1355612-71-3
|
|
|
Aldose reductase-IN-1 is a aldose reductase inhibitor (IC50: 28.9 pM).
|
T17114 |
Tolrestat
|
82964-04-3
|
100%
|
|
Tolrestat is a potent inhibitor of aldose reductase (IC50 = 35 nM).
|
T3378 |
Alpha-Estradiol
|
57-91-0
|
100%
|
|
Endogenous estrogen receptor ligand (Ki values are 0.2 and 1.2 nM for ERα and ERβ receptors respectively).
|
T6102 |
2'-acetylacteoside
|
94492-24-7
|
97.38%
|
|
2'-Acetylacteoside has antioxidative activity. It can significantly attenuate glutamate-induced neurotoxicity at concentrations ranging from 0.1 to 10 μM. 2'-Ace...
|
T5S0543 |
Isocurcumenol
|
24063-71-6
|
98%
|
|
1. Isocurcumenol inhibits 5α-reductase which converts testosterone to dihydrotestosterone (DHT).
|
T7478 |
2-Chloro-1-(4-fluorobenzyl)benzimidazole
|
84946-20-3
|
98%
|
|
2-Chloro-1-(4-fluorobenzyl)benzimidazole is an inhibitor of aldose reductase (ALR2).
|
T3665 |
Tectoridin
|
611-40-5
|
99.02%
|
|
Tectoridin possesses an estrogenic and thyroid hormone-like agent by activating estrogen and thyroid hormone receptors. Tectoridin has anti-oxidant, anti-inflamm...
|
T0488 |
Finasteride
|
98319-26-7
|
99.04%
|
|
Finasteride is an oral inhibitor of active testosterone 5-alpha-reductase and Ki value is 10 nM.
|
T15568 |
Imirestat
|
89391-50-4
|
99.08%
|
|
Imirestat is an aldose reductase inhibitor. It is used for the treatment of diabetes.
|
T1458 |
Epalrestat
|
82159-09-9
|
99.2%
|
|
Epalrestat, an aldose reductase inhibitor, is well tolerated in Long-term therapy. It can effectually ameliorate the associated symptoms of diabetic neuropathy a...
|
TN2601 |
12-O-Methylcarnosic acid
|
62201-71-2
|
99.24%
|
|
12-O-Methylcarnosic acid is a diterpene carnosic acid isolated from the acetone extract of Salvia microphylla, is an active constituent of 5α-reductase inhibitio...
|
T10393 |
AT-007
|
2170729-29-8
|
99.36%
|
|
AT-007 is an orally active CNS penetrant Aldose Reductase inhibitor for the treatment of Galactosemia (IC50: 100 pM). It reduces toxic galactitol levels and prev...
|