T3198 |
Pre-084
|
138847-85-5
|
|
|
Pre-084 is a high affinity, selective σ1 agonist.
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T4620 |
Siramesine
|
147817-50-3
|
|
|
Siramesine (Lu 28-179)(Lu 28-179) is a selective sigma-2 receptor agonist, which has been shown to trigger cell death of cancer cells and to exhibit a potent ant...
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T78086 |
S1R agonist 1 hydrochloride
|
242487-82-7
|
98%
|
|
S1R Agonist 1 (Compound 6b) hydrochloride is a selective S1R agonist, displaying K i values of 0.93 nM for S1R and 72 nM for S2R, and has demonstrated neuroprote...
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T78087 |
S1R agonist 2 hydrochloride
|
|
98%
|
|
Compound 8b hydrochloride, a selective S1R agonist, exhibits affinity with K i s of 1.1 nM for S1R and 88 nM for S2R. It demonstrates neuroprotective effects aga...
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T78734 |
Sigma-1 receptor antagonist 5
|
|
98%
|
|
Sigma-1 receptor antagonist 5 (compound 12), a 4-pyridylpiperidine derivative, exhibits analgesic properties through its antagonistic action on sigma receptors (...
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T78915 |
AD186
|
|
98%
|
|
AD186, a potent and selective S1R agonist, exhibits dissociation constants (Kis) of 2.7 nM for S1R and 27 nM for S2R. Notably, AD186 completely reverses the anti...
|
T78916 |
AB21 oxalate
|
|
98%
|
|
AB21 oxalate, a potent and selective S1R antagonist, exhibits binding affinities (Kis) of 13 nM and 102 nM for S1R and S2R, respectively. It effectively reduces ...
|
T79356 |
SARS-CoV-2-IN-57
|
1265624-68-7
|
98%
|
|
SARS-CoV-2-IN-57 (compound (+)-R-26) is a potent inhibitor of SARS-CoV-2 with an IC50 of 80 nM and demonstrates high affinity for the Sigma Receptor, exhibiting ...
|
T79666 |
WLB-89462
|
2849471-75-4
|
98%
|
|
WLB-89462 (Compound 20c) is a selective σ2 receptor ligand with a K i of 13 nM, exhibiting neuroprotective properties and the ability to ameliorate Aβ peptide-in...
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T19342 |
Glycerol phenylbutyrate-D5
|
T19342
|
98%
|
|
Glycerol phenylbutyrate-D5 is a deuterium-labeled Glycerol phenylbutyrate. Glycerol phenylbutyrate is a sigma-2 (σ2) receptor ligand (pKi: 8.02).
|
T19341 |
Glycerol phenylbutyrate-D15
|
T19341
|
98%
|
|
Glycerol phenylbutyrate-D15 is a deuterium-labeled Glycerol phenylbutyrate. Glycerol phenylbutyrate is a sigma-2 (σ2) receptor ligand (pKi: 8.02).
|
T16445 |
PD 144418
|
154130-99-1
|
98%
|
|
PD 144418 displays potential antipsychotic activity. PD 144418 is a high affinity, potent and selective sigma 1 (σ1) receptor ligand (Ki: 0.08 nM and 1377 nM for...
|
T4111 |
Blarcamesine hydrochloride
|
195615-84-0
|
99.95%
|
|
Blarcamesine hydrochloride (AVex-73 hydrochloride) is a Sigma-1 Receptor agonist (IC50: 860 nM).
|
T77340L |
AB21 HCl
|
|
99.89%
|
|
AB21 HCl is a selective antagonist of the σ1 receptor, with Kis of 13 nM for σ1 receptor and 102 nM for σ2 receptor. AB21 HCl is known for its ability to reduce ...
|
T12910 |
Sigma-1 receptor antagonist 1
|
1639220-19-1
|
99.81%
|
|
Sigma-1 receptor antagonist 1 is an effective and selective antagonist of sigma-1 receptor. Sigma-1 receptor antagonist 1 exhibits antineuropathic pain activity ...
|
T9244 |
σ1 Receptor antagonist-1
|
1204401-49-9
|
99.68%
|
|
σ1 Receptor antagonist-1 is a selective sigma 1 receptor antagonist.
|
T5027 |
Dimemorfan phosphate
|
36304-84-4
|
99.67%
|
|
Dimemorfan phosphate (3,17-dimethylmorphinan) is a sigma 1 receptor agonist. Dimemorfan phosphate is used as a potent antitussive.
|
T4229 |
S1RA hydrochloride
|
1265917-14-3
|
99.65%
|
|
S1RA hydrochloride (E-52862 hydrochloride) is an effective and specific sigma-1 receptor(σ1R, Ki: 17 nM) antagonist, and has good selectivity against σ2R (Ki > 1...
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T22240 |
Amitriptyline
|
50-48-6
|
99.64%
|
|
Amitriptyline (MK-230, N-750, Ro41575) is a tricyclic antidepressant (TCA) with analgesic properties. Amitriptyline is widely used to treat depression and neurop...
|
T3198L |
PRE-084 hydrochloride
|
75136-54-8
|
99.61%
|
|
PRE-084 hydrochloride is a selective agonist of σ1(IC50:44 nM, in the sigma receptor assay).
|