T22240 |
Amitriptyline
|
50-48-6
|
99.64%
|
|
Amitriptyline (MK-230, N-750, Ro41575) is a tricyclic antidepressant (TCA) with analgesic properties. Amitriptyline is widely used to treat depression and neurop...
|
T3198L |
PRE-084 hydrochloride
|
75136-54-8
|
99.61%
|
|
PRE-084 hydrochloride is a selective agonist of σ1(IC50:44 nM, in the sigma receptor assay).
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T22513 |
4-PPBP maleate
|
201216-39-9
|
99.54%
|
|
4-PPBP maleate is a potent σ1 receptor (ligand) agonist. 4-PPBP maleate can be considered a selective, non-competitive NR1a/2B NMDA receptor antagonist in the co...
|
T12911 |
Sigma-1 receptor antagonist 2
|
1639220-15-7
|
99.52%
|
|
Sigma-1 receptor antagonist 2 is a potent and selective antagonist of sigma 1 receptor (σ1 R) (σ1 and σ2 receptor with Kis of 3.88 and 1288 nM , respectively).
|
T8834 |
EST64454 hydrochloride
|
1950569-11-5
|
99.15%
|
|
EST64454 hydrochloride (EST64454) is a highly soluble σ1 receptor antagonist (Ki : 22 nM),has the potential for Pain Management.
|
T4596 |
4-IBP
|
155798-08-6
|
99.12%
|
|
4-IBP is a selective σ1 agonist with a high level of affinity for the σ1 receptor (Ki = 1.7 nM) and a moderate affinity for the σ2 receptor (Ki = 25.2 nM) .
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T39211 |
PD 144418 oxalate
|
1794760-28-3
|
99.08%
|
|
PD 144418 oxalate is a highly potent and selective sigma 1 (σ1) receptor ligand, displaying a Ki value of 0.08 nM for σ1 and 1377 nM for σ2. It exhibits negligib...
|
T72059 |
S1R agonist 2
|
150085-21-5
|
99.04%
|
|
S1R agonist 2 is a selective S1R agonist with a Ki of 88 nM for S2R and 1.1 nM for S1R and is protective against ROS and NMDA-induced neurotoxicity.
|
T67739 |
BMY-14802
|
105565-56-8
|
98.93%
|
|
BMY-14802 (alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol) is a selective and orally active sigma-1 antagonist with an IC50 of 112 nM.
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T20797 |
NE-100 hydrochloride
|
149409-57-4
|
98.85%
|
|
NE-100 hydrochloride (NE-100 HCl) is a potent and selective antagonist of σ1 (IC50 = 4.16 nM) with antipsychotic activity. NE100 HCl also suppresses ER stress-in...
|
T3597 |
Cutamesine dihydrochloride
|
165377-44-6
|
98.83%
|
|
Cutamesine dihydrochloride (SA4503 dihydrochloride) is a selective σ1 receptor agonist (IC50: 17.4 nM). It shows selectivity for σ1 over σ2 receptors, and inhibi...
|
T22612 |
BMY-14802 hydrochloride
|
105565-55-7
|
98.64%
|
|
BMY-14802 hydrochloride (BMS 181100 hydrochloride) is a selective antagonist of σ receptor (IC50 = 112 nM) with antipsychotic effects. BMY-14802 hydrochloride is...
|
T62396L |
KB-5492 FA
|
|
98.54%
|
|
KB-5492 FA is a selective sigma receptor inhibitor with antiulcerogenic effects.CAS 번호128-52-56-8
|
T5969 |
Ditolylguanidine
|
97-39-2
|
98%
|
|
Ditolylguanidine (Di-o-tolylguanidine) is an agonist of sigma receptor (σ1/σ2 receptor).
|
T7488 |
BD1063 dhydrochloride
|
206996-13-6
|
98%
|
|
BD1063 dhydrochloride is a potent and selective sigma 1(σ1) receptor antagonist(Ki = 9 nM).
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T21788 |
BD 1008 dihydrobromide
|
138356-09-9
|
97.81%
|
|
BD 1008 dihydrobromide is a selective antagonist of the sigma 1 (σ1) receptor (Ki = 2 nM). BD 1008 dihydrobromide have high affinity for sigma1 receptors, modera...
|
T15034 |
Roluperidone
|
359625-79-9
|
96.46%
|
|
Roluperidone (CYR-101) is a novel cyclic amide derivative. It has high equipotent affinities for 5-HT2A and σ2 receptors (Ki of 7.53 nM and 8.19 nM for 5-HT2A an...
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T1180 |
Blonanserin
|
132810-10-7
|
100%
|
|
Blonanserin (AD-5423) is an atypical antipsychotic approved in Japan in January, 2008. Relative to many other antipsychotics, blonanserin has an improved tolerab...
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T12912 |
Sigma-1 receptor antagonist 3
|
1639220-17-9
|
100%
|
|
Sigma-1 receptor antagonist 3 is a potent and selective antagonist of Sigma-1 (σ1) receptor(Ki : 1.14 nM), has the potential for the neuropathic pain.
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T13510 |
Sigma-LIGAND-1
|
139652-01-0
|
100%
|
|
Sigma-LIGAND-1 is a selective Sigma Receptor ligand with an IC50s of 16 nM, 19 nM at the DTG site and the PPP site, respectively. Sigma-LIGAND-1 has a Ki of 4000...
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