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Syk

Tyrosine-protein kinase SYK, also known as spleen tyrosine kinase, is an enzyme which in humans is encoded by the SYK gene.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T4348 Syk Inhibitor II 726695-51-8 97.63%
Syk Inhibitor II
Syk inhibitor II, a cell-permeable, ATP-competitive, pyrimidine-carboxamide compound, selectively and reversibly inhibits Syk (IC50 = 41 nM).
T16995 TAS05567 1429038-15-2 98%
TAS05567
TAS05567 is a potent, highly selective, and ATP-competitive Syk inhibitor (IC50: 0.37 nM). TAS05567 only shows >70% inhibition of Syk and 4 other kinases (FLT3, ...
T11824 Lanraplenib succinate 1800047-00-0 98%
Lanraplenib succinate
Lanraplenib succinate inhibits SYK activity in platelets via the glycoprotein VI (GPVI) receptor without prolonging bleeding time (BT) in monkeys or humans. Lanr...
T78641 ER-27319 201010-95-9 98%
ER-27319
ER-27319, an acridone derivative, serves as a potent and selective inhibitor of spleen tyrosine kinase (SYK), effectively impeding both the tyrosine phosphorylat...
T78943 Syk-IN-7 98%
Syk-IN-7
Syk-IN-7 (compound 17) acts as an inhibitor of spleen tyrosine kinase (SYK) [1].
T79443 Syk-IN-8 2568963-01-7 98%
Syk-IN-8
Syk-IN-8 (compound 19q) functions as a Syk inhibitor with demonstrated antiproliferative effects on a variety of hematological tumor cells. It specifically inhib...
T28281 OXSI-2 622387-85-3 98%
OXSI-2
OXSI-2 (Syk Inhibitor) is an inhibitor of Syk with an EC50 of 313 nM and an IC50 of 14 nM. OXSI-2 completely inhibits Adaptor protein LAT Y191 phosphorylation an...
T11824L Lanraplenib monosuccinate 1800046-97-2 98%
Lanraplenib monosuccinate
Lanraplenib monosuccinate inhibits SYK activity in platelets via the glycoprotein VI (GPVI) receptor without prolonging bleeding time (BT) in monkeys or humans. ...
TN1549 Damnacanthal 477-84-9 98%
Damnacanthal
Damnacanthal possesses anti-cancer, immunomodulatory, antinociceptive and anti-inflammatory actions, it can treat or prevent hepatocellular carcinoma through its...
TN7075 Linocinnamarin 554-87-0 99.95%
Linocinnamarin
Linocinnamarin (3-[4-(beta-D-Glucopyranosyloxy)phenyl]acrylic acid methyl ester) is isolated from Fragaria ananassa Duch. (strawberry). The inhibition of antigen...
T2696 PRT062607 hydrochloride 1370261-97-4 99.93%
PRT062607 hydrochloride
PRT062607 hydrochloride (P505-15 Hydrochloride) is a selective inhibitor of Syk (IC50: 1 nM). It displays at least 80-fold selectivity for Syk over other kinases...
T0465 Ellagic acid 476-66-4 99.76%
Ellagic acid
Ellagic acid (Gallogen) is a fused four ring compound isolated from the kino of Eucalyptus maculata Hook and E. Hemipholia F. Muell. Activates Factor XII of the ...
T2487 Cerdulatinib 1198300-79-6 99.64%
Cerdulatinib
Cerdulatinib (PRT2070) is an novel oral dual Syk/JAK inhibitor.
T14331 Gusacitinib 1425381-60-7 99.58%
Gusacitinib
Gusacitinib (ASN-002) (ASN-002) is spleen tyrosine kinase (SYK) and janus kinase (JAK) inhibitor (IC50: 5-46 nM).
T6776 BAY 61-3606 dihydrochloride 648903-57-5 99.46%
BAY 61-3606 dihydrochloride
BAY 61-3606 dihydrochloride (BAY 61-3606) is a potent and selective inhibitor of Syk kinase (Ki = 7.5 nM).
T11824LL Lanraplenib 1800046-95-0 99.42%
Lanraplenib
Lanraplenib (GS-9876) is a highly selective and orally active SYK inhibitor (IC50=9.5 nM) in development for the treatment of inflammatory diseases. Lanraplenib ...
T0610 Piceatannol 10083-24-6 99.39%
Piceatannol
Piceatannol (Astringenin) is an anti-inflammatory, immunomodulatory and antiproliferative agent. It inhibits p56lck and syk protein tyrosine kinases and inhibits...
T2467 R406 free base 841290-80-0 99.31%
R406 free base
R406 free base (R406 (free base)) is a potent Syk inhibitor.
T4209 TAK-659 hydrochloride 1952251-28-3 99.28%
TAK-659 hydrochloride
TAK-659 hydrochloride (TAK-659) is a potent and selective inhibitor of spleen tyrosine kinase (SYK) with an IC50 value of 3.2 nM. It is selective against most ot...
T6104 Cerdulatinib hydrochloride 1369761-01-2 99.23%
Cerdulatinib hydrochloride
Cerdulatinib hydrochloride (PRT2070 hydrochloride) is an oral active, multi-targeted tyrosine kinase inhibitor with IC50 of 12 nM/6 nM/8 nM/0.5 nM and 32 nM for ...
Syk Inhibitor II
T4348
Syk inhibitor II, a cell-permeable, ATP-competitive, pyrimidine-carboxamide compound, selectively and reversibly inhibits Syk (IC50 = 41 nM).
TAS05567
T16995
TAS05567 is a potent, highly selective, and ATP-competitive Syk inhibitor (IC50: 0.37 nM). TAS05567 only shows >70% inhibition of Syk and 4 other kinases (FLT3, ...
Lanraplenib succinate
T11824
Lanraplenib succinate inhibits SYK activity in platelets via the glycoprotein VI (GPVI) receptor without prolonging bleeding time (BT) in monkeys or humans. Lanr...
ER-27319
T78641
ER-27319, an acridone derivative, serves as a potent and selective inhibitor of spleen tyrosine kinase (SYK), effectively impeding both the tyrosine phosphorylat...
Syk-IN-7
T78943
Syk-IN-7 (compound 17) acts as an inhibitor of spleen tyrosine kinase (SYK) [1].
Syk-IN-8
T79443
Syk-IN-8 (compound 19q) functions as a Syk inhibitor with demonstrated antiproliferative effects on a variety of hematological tumor cells. It specifically inhib...
OXSI-2
T28281
OXSI-2 (Syk Inhibitor) is an inhibitor of Syk with an EC50 of 313 nM and an IC50 of 14 nM. OXSI-2 completely inhibits Adaptor protein LAT Y191 phosphorylation an...
Lanraplenib monosuccinate
T11824L
Lanraplenib monosuccinate inhibits SYK activity in platelets via the glycoprotein VI (GPVI) receptor without prolonging bleeding time (BT) in monkeys or humans. ...
Damnacanthal
TN1549
Damnacanthal possesses anti-cancer, immunomodulatory, antinociceptive and anti-inflammatory actions, it can treat or prevent hepatocellular carcinoma through its...
Linocinnamarin
TN7075
Linocinnamarin (3-[4-(beta-D-Glucopyranosyloxy)phenyl]acrylic acid methyl ester) is isolated from Fragaria ananassa Duch. (strawberry). The inhibition of antigen...
PRT062607 hydrochloride
T2696
PRT062607 hydrochloride (P505-15 Hydrochloride) is a selective inhibitor of Syk (IC50: 1 nM). It displays at least 80-fold selectivity for Syk over other kinases...
Ellagic acid
T0465
Ellagic acid (Gallogen) is a fused four ring compound isolated from the kino of Eucalyptus maculata Hook and E. Hemipholia F. Muell. Activates Factor XII of the ...
Cerdulatinib
T2487
Cerdulatinib (PRT2070) is an novel oral dual Syk/JAK inhibitor.
Gusacitinib
T14331
Gusacitinib (ASN-002) (ASN-002) is spleen tyrosine kinase (SYK) and janus kinase (JAK) inhibitor (IC50: 5-46 nM).
BAY 61-3606 dihydrochloride
T6776
BAY 61-3606 dihydrochloride (BAY 61-3606) is a potent and selective inhibitor of Syk kinase (Ki = 7.5 nM).
Lanraplenib
T11824LL
Lanraplenib (GS-9876) is a highly selective and orally active SYK inhibitor (IC50=9.5 nM) in development for the treatment of inflammatory diseases. Lanraplenib ...
Piceatannol
T0610
Piceatannol (Astringenin) is an anti-inflammatory, immunomodulatory and antiproliferative agent. It inhibits p56lck and syk protein tyrosine kinases and inhibits...
R406 free base
T2467
R406 free base (R406 (free base)) is a potent Syk inhibitor.
TAK-659 hydrochloride
T4209
TAK-659 hydrochloride (TAK-659) is a potent and selective inhibitor of spleen tyrosine kinase (SYK) with an IC50 value of 3.2 nM. It is selective against most ot...
Cerdulatinib hydrochloride
T6104
Cerdulatinib hydrochloride (PRT2070 hydrochloride) is an oral active, multi-targeted tyrosine kinase inhibitor with IC50 of 12 nM/6 nM/8 nM/0.5 nM and 32 nM for ...
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TargetMol