TN5147 |
Tilifodiolide
|
126724-95-6
|
98%
|
|
Tilifodiolide exerts in vitro and in vivo anti-inflammatory activity and in vivo antinociceptive effects. Tilifodiolide exerted antidiarrheal activity by decreas...
|
TN3587 |
Capillarisin
|
56365-38-9
|
98%
|
|
Capillarisin is a novel blocker of STAT3 activation and thus may have a potential in negative regulation of growth, metastasis, and chemoresistance of tumor cell...
|
TN5164 |
Trans-Hinokiresinol
|
17676-24-3
|
98%
|
|
Hinokiresinol is a novel inhibitor of LTB4 binding to the human neutrophils, it has antiallergic effect, it inhibits IgE-induced mouse passive cutaneous anaphyla...
|
TN4938 |
Samidin
|
477-33-8
|
98%
|
|
Samidin has anti-inflammatory properties through suppression of NF-κB and AP-1-mediated-genes in lipopolysaccharide (LPS)-stimulated RAW 264.7 cells.
|
TN3635 |
Chlojaponilactone B
|
1449382-91-5
|
98%
|
|
Chlojaponilactone B has anti-inflammatory activity, it exhibits pronounced inhibition of nitric oxide (NO) production in lipopolysaccharide (LPS)-induced RAW 264...
|
TN4592 |
Murrangatin
|
37126-91-3
|
98%
|
|
Murrangatin may be a valuable anti-tumor-promoting agent, it can significantly inhibit Epstein-Barr virus early antigen (EBV-EA) activation, and preserve the hig...
|
T3123 |
Allicin
|
539-86-6
|
98%
|
|
Allicin exerts antioxidant, bactericidal, anti-cancer, anti-inflammatory activities, it exerts an inhibitory immunomodulatory effect on intestinal epithelial cel...
|
T37445 |
Etanercept
|
185243-69-0
|
98%
|
|
Etanercept is a dimeric fusion protein that serves as a competitive TNF inhibitor by binding to TNF. It effectively inhibits the binding of both TNF-α and TNF-β ...
|
TN1660 |
Ganoderic acid C1
|
95311-97-0
|
98%
|
|
Ganoderic acid C1 has anti-inflammatory activity, has potential for treating TNF-α± mediated inflammation in asthma and other inflammatory diseases. Ganoderic ac...
|
T2S1040 |
Jolkinolide B
|
37905-08-1
|
98%
|
|
Jolkinolide B is a bioactive diterpene isolated from the roots of Euphorbia fischeriana Steud. Jolkinolide B induces apoptosis in cancer cells. Jolkinolide B can...
|
T14848 |
C 87
|
332420-90-3
|
98%
|
|
C 87 is a small-molecule TNF-α inhibitor. C 87 directly binds to TNFα, potently inhibits TNF-α-induced cytotoxicity (IC50 = 8.73 μM), and effectively blocks TNF-...
|
TN7235 |
4-methoxylonchocarpin
|
51589-67-4
|
98%
|
|
4-methoxylonchocarpin was isolated from the roots of Abrus precatorius as a potent anti-inflammatory compound. 4-methoxylonchocarpin inhibited NF-κB-activated TN...
|
TN1403 |
Arjunolic acid
|
465-00-9
|
98%
|
|
Arjunolic acid has antioxidant, anti-inflammatory, antinociceptive and anticholinesterasic (AChE and BuChE) activities, it may as promising targets for the devel...
|
T12985 |
SPD304 dihydrochloride
|
1049741-03-8
|
98%
|
|
SPD304 dihydrochloride is a selective inhibitor of TNF-α with an IC50 of 22 µM. SPD304 dihydrochloride promotes dissociation of TNF trimers.
|
TN4583 |
Moringin
|
73255-40-0
|
98%
|
|
Moringin is an isothiocyanate obtained from myrosinase-mediated hydrolysis of the glucosinolate precursor glucoMoringin present in Moringa oleifera seeds. Moring...
|
T3280 |
Clodronate disodium tetrahydrate
|
88416-50-6
|
98%
|
|
Disodium clodronate tetrahydrate inhibits bone resorption and soft tissue calcification.
|
T9921 |
Infliximab
|
170277-31-3
|
98%
|
|
Infliximab is a humanized antibody against tumor necrosis factor α TNF-α) that is used in the treatment of Crohn's disease and rheumatoid arthritis.
|
TC0036 |
Compound Lup-20(29)-en-3-yl acetate
|
TC0036
|
98%
|
|
Lupeol acetate, a derivative of Lupeol, inhibits the progression of rheumatoid arthritis by downregulating TNF-α, IL-1β, MCP-1, COX-2, VEGF and granzyme B.
|
T9901 |
Adalimumab
|
331731-18-1
|
98%
|
|
Adalimumab anti-TNF-alpha) is the first fully human recombinant IgG1 monoclonal antibody that specifically targets human TNF-alpha.
|
T5785 |
MALTOTETRAOSE
|
34612-38-9
|
98%
|
|
MALTOTETRAOSE are potent inhibitors of TNF-α-induced intercellular adhesion molecule-1 (ICAM-1) expression, maltotetraose may be beneficial in the suppression of...
|