TN1996 |
Nothofagin
|
11023-94-2
|
99.21%
|
|
Nothofagin has antioxidant, and antithrombotic activities, it possesses anti-inflammatory activity by inhibiting hyperpermeability, expression of CAMs, and adhes...
|
T13824 |
PP58
|
212391-58-7
|
99.21%
|
|
PP58 is an inhibitor of PDGFR, FGFR and Src family.
|
T10865 |
Cot inhibitor-1
|
915365-57-0
|
99.19%
|
|
Cot inhibitor-1 is a selective inhibitor of Cot protein kinase (also known as Tpl2 or MAP3K8) (IC50 at 28 nM). Cot inhibitor-1 inhibited TNF-alpha production in ...
|
T5S2129 |
Sciadopitysin
|
521-34-6
|
99.17%
|
|
Sciadopitysin may prevent the development of diabetic osteopathy, it exerts its therapeutic effects via upregulation of mitochondrial biogenesis.Sciadopitysin sh...
|
T6S1597 |
Mulberroside A
|
102841-42-9
|
99.05%
|
|
1. Mulberroside has nephroprotective, hypoglycemic, and antidiabetic effects. 2. Mulberroside A is a glycosylated stilbene of oxyresveratrol; thus, the deglycosy...
|
TN2064 |
Physcion 8-O-β-D-glucopyranoside
|
23451-01-6
|
99.04%
|
|
Physcion 8-O-β-D-glucopyranoside (Physcion 8-O-beta-D-monoglucoside) has anti-inflammatory and anti-cancer activities. Physcion 8-O-β-D-glucopyranoside can be us...
|
T0122 |
Bergenin
|
477-90-7
|
99.01%
|
|
Bergenin (Bengenin) is a polyphenol, which is an effective antinarcotic agent with antioxidant action.
|
T0875 |
Acetylcysteine
|
616-91-1
|
98.98%
|
|
Acetylcysteine (NAC) is an N-acetyl derivative of cysteine, a ROS inhibitor and mucolytic agent. Acetylcysteine induces apoptosis, can be used to reduce mucus th...
|
T6S0627 |
Mesaconitine
|
2752-64-9
|
98.98%
|
|
1. Mesaconitine has antiinflammatory activity. 2. Mesaconitine has antinociceptive activity through cyclic AMP and stimulation of the central β-adrenergic system...
|
T4637 |
R-7050
|
303997-35-5
|
98.95%
|
|
R-7050 (TNF-α Antagonist III), a tumor necrosis factor receptor (TNFR) antagonist, exhibits heightened selectivity for TNFα.
|
T2S2264 |
Linalool
|
78-70-6
|
98.95%
|
|
1. Linalool (Linalol), a natural compound of the essential oils, has been shown to have antinociceptive, antimicrobial, and anti-inflammatory properties. 2. Lina...
|
T4S0227 |
Sinensetin
|
2306-27-6
|
98.93%
|
|
Sinensetin (Pedalitin permethyl ether) is a methylated flavone found in certain citrus fruits. pocess potent antiangiogenesis and anti-inflammatory, sinensetin e...
|
T60657 |
(R)-STU104
|
2767124-77-4
|
98.91%
|
|
(R)-STU104 is a novel TAK1-MKK3 protein-protein interaction (PPI) inhibitor that inhibits TNF-α and suppresses the TAK1/MKK3/p38/MnK1/MK2/elF4E signalling pathwa...
|
T1738 |
Taxifolin
|
480-18-2
|
98.9%
|
|
Taxifolin (Dihydroquercetin) is a flavonoid in many plants such as Taxus chinensis, Siberian larch, Cedrus deodara and so on.
|
T3S1641 |
Esculentoside H
|
66656-92-6
|
98.9%
|
|
Phytolaccaceae has anti-tumor activity, the mechanism may be related to the capacity of Esculentoside H for TNF release.
|
T2367 |
SKF-86002
|
72873-74-6
|
98.89%
|
|
SKF-86002 is an effective inhibitor of p38 MAP kinase (IC50: 0.5-1 uM); inhibits LPS-induced IL-1 and TNF-α production in human monocytes (IC50: 1 μM).
|
T10866 |
Cot inhibitor-2
|
915363-56-3
|
98.87%
|
|
Cot inhibitor-2 is a cot (Tpl2/MAP3K8) inhibitor (IC50: 1.6 nM) with potency, selectivity and oral activity. cot inhibitor-2 inhibits LPS-stimulated TNF-α produc...
|
T29857 |
Alethine
|
646-08-2
|
98.82%
|
|
Alethine (β-Alethine) is a small molecule compound with antitumour activity and is used to treat tumours and infections. The alethine-induced up-regulation of TN...
|
T10730 |
CDC801
|
192819-27-5
|
98.81%
|
|
CDC801 is an inhibitor of PDE4 and TNF-α with IC50s of 1.1 μM and 2.5 μM, respectively.
|
T2384 |
Pomalidomide
|
19171-19-8
|
98.8%
|
|
Pomalidomide (CC-4047) inhibits TNF-α release in LPS stimulated human PBMCs (IC50: 13 nM). It is an anti-angiogenic agent and an immunomodulator.
|