TN5133 |
3',5,5',7-Tetrahydroxy-4',6-dimethoxyflavone
|
125537-92-0
|
98%
|
|
5,7,3',5'-tetrahydroxy-6,4'-dimethoxyflavone exhibits anti-HIV-1 activity in the anti-syncytium assay using (∆Tat/rev)MC99 virus and 1A2 cell line system, it sho...
|
TN2953 |
3-Hydroxysarpagine
|
857297-90-6
|
98%
|
|
3-Hydroxysarpagine is a natural product of Rauvolfia, Apocynaceae. The catalog number is TN2953 and the CAS number is 857297-90-6. 3-Hydroxysarpagine can be used...
|
T67909 |
TAK1 inhibitor
|
1326712-16-6
|
98%
|
|
TAK1 inhibitor is an inhibitor, which can inhibit MCF-7, A549, DU-145 and MDA MB-231, with IC50 of 0.021, 0.14, 0.064 and 0.19, respectively. TAK1 inhibitor show...
|
TN4283 |
Isodiospyrin
|
20175-84-2
|
98%
|
|
Isodiospyrin is a novel human DNA topoisomerase I inhibitor, it exhibits cytotoxic activity to tumor cell lines. Isodiospyrin has antibacterial activity, the min...
|
TN1886 |
Lucidin primeveroside
|
29706-59-0
|
98%
|
|
Lucidin primeveroside (Lucidin 3-O-primeveroside) is a natural product isolated from the root powder of akane (Rubia akane) and can be used as a coloring agent a...
|
TN4422 |
Lauterine
|
28200-65-9
|
98%
|
|
Lauterine is a DNA topoisomerase inhibitor.
|
T15586 |
Intoplicine
|
125974-72-3
|
98%
|
|
Intoplicine is an inhibitor of DNA topoisomerase I and II.
|
TN1169 |
1,4-Dihydroxy-2-carbomethoxy-3-prenylnaphthalene-1-O-β-D-glucopyranoside
|
1415729-43-9
|
98%
|
|
1,4-Dihydroxy-2-carbomethoxy-3-prenylnaphthalene-1-O-beta-glucopyranoside may have DNA topoisomerases I and II inhibitory activity and cytotoxicity.
|
T14945 |
CH-0793076
|
534605-78-2
|
98%
|
|
CH-0793076, a hexacyclic camptothecin analog, is an active drug and major metabolite of TP300. CH-0793076 is efficacious against cells expressing BCRP (breast ca...
|
TQ0134 |
Podocarpusflavone A
|
22136-74-9
|
98%
|
|
Podocarpusflavone A is a DNA topoisomerase I inhibitor. It has moderated anti-proliferative activity induce cell apoptosis in MCF-7.
|
TN4107 |
Ganoderic acid X
|
86377-53-9
|
98%
|
|
Ganoderic acid X is a potential Mdm2 inhibitor(K(i) = 16nM). It is a potential anticancer drug, inhibits topoisomerases and induces apoptosis of cancer cells.
|
TN4923 |
Rubicordifolin
|
849699-55-4
|
98%
|
|
Rubicordifolin exhibits potent cytotoxic and antitumor activities.
|
T1703 |
SN-38
|
86639-52-3
|
99.97%
|
|
SN-38 (NK012) is an active metabolite of CPT-11.
|
T3332 |
Isosteviol
|
27975-19-5
|
99.97%
|
|
Isosteviol ((-)-Isosteviol), a common natural sweetener, belongs to tetracyclic diterpene glycosides. The pharmacology researches have suggested that stevioside ...
|
T28994L |
Topixantrone 2HCl
|
2514569-86-7
|
99.96%
|
|
Topixantrone 2HCl is a DNA topoisomerase inhibitor with antitumor activity for the study of gastric and prostate cancer.
|
T1095 |
Sparfloxacin
|
110871-86-8
|
99.95%
|
|
Sparfloxacin (CI-978) is a fluoroquinolone antibiotic that inhibits bacterial DNA gyrase, thereby inhibiting DNA replication and transcription.
|
T3186 |
NU2058
|
161058-83-9
|
99.95%
|
|
NU2058 (O(6)-Cyclohexylmethylguanine) is a guanine-based CDK inhibitor, also inhibits DNA topoisomerase II ATPase activity.
|
T0909L |
Nalidixic acid sodium salt
|
3374-05-8
|
99.94%
|
|
Nalidixic acid sodium salt (Baktogram) is an antimicrobial agent with a limited bacteriocidal spectrum.
|
T9088 |
Topovale
|
500214-53-9
|
99.94%
|
|
Topovale (ARC111) is a potent inhibitor of topoisomerase I. Topovale inhibits hypoxia-mediated accumulation of hypoxia-inducible factor-1alpha. Topovale exhibite...
|
T0132 |
Etoposide
|
33419-42-0
|
99.93%
|
|
Etoposide (VP-16-213) is a topoisomerase II inhibitor that inhibits DNA synthesis by forming a complex with topoisomerase II and DNA (IC50=60.3 μM). Etoposide ha...
|