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Phytohemagglutinin P
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Catalog No. T78491
Alias PHA-P
Phytohemagglutinin P (PHA-P) is a mitogen that selectively stimulates hematogenous or lymphoid monocytic cells [1].
Phytohemagglutinin P
Phytohemagglutinin P
😃Good
Catalog No. T78491Alias PHA-P
Phytohemagglutinin P (PHA-P) is a mitogen that selectively stimulates hematogenous or lymphoid monocytic cells [1].
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $73 | 7-10 days | |
| 5 mg | $185 | 7-10 days | |
| 10 mg | $278 | 7-10 days | |
| 25 mg | $473 | 7-10 days | |
| 50 mg | $710 | 7-10 days |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Phytohemagglutinin P (PHA-P) is a mitogen that selectively stimulates hematogenous or lymphoid monocytic cells [1]. |
| In vitro | Activation of decidual CD8+ T lymphocytes by phytohemagglutinin-P (10 μg/ml; 24-48 hours) increases interferon gamma and interleukin (IL) 8 production, while decreasing granulocyte-macrophage colony-stimulating factor (CSF2), IL1B, IL2, IL6, IL10, IL12, and tumor necrosis factor secretion, independent of gestational age [2]. |
| In vivo | Phytohemagglutinin-P, administered intraperitoneally at doses of 25 and 50 mg/kg daily for 15 days to male Sprague-Dawley rats, resulted in a reduction of longitudinal bone growth, chondrocyte numbers, cartilage plate thickness, metaphyseal hard tissue mass, calcified cartilage core percentage, and osteoblast count per millimeter of bone surface. Furthermore, PHA-P elevated osteoclast quantity, osteoclastic nuclei labeling, and the average nuclei count per osteoclast [1]. |
| Alias | PHA-P |
Storage & Solubility Information
| Storage | Shipping with blue ice. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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