βcatenin/cbpin1

hCA/Wnt/β-catenin-IN-1 (Compd 15) serves as an inhibitor with selective affinity for hCA isoforms II, IX, and XII, exhibiting K i values of 33.6, 24.1, and 6.8 nM, respectively. Additionally, this compound attenuates P-gp activity and impedes the Wnt/β-catenin signaling pathway. Furthermore, it compromises the viability of cancer cells, specifically targeting the NCI/ADR-RES DOX-resistant cell line [1].

β-catenin/CBP-IN-1 is a potent and selective inhibitor of CBP/β-catenin

β-Catenin modulator-1 (IIa-650) is a useful agent in cancer research for modulating β-Catenin [1].

PTK7/β-catenin-IN-1 (compound 01065) is a potent inhibitor targeting PTK7/β-catenin and p53/MDM2, with IC50 values of 8.9 μM and 56.5 μM, respectively. This compound shows promise for cancer research applications [1].

Wnt/β-catenin agonist 1 is an agonist of Wnt/β-catenin signalling pathway(EC50 of 0.27 μM).