Search Result

Search Results for " aquaporin "

Targets

Compounds

Natural Products

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T5102	TGN-020	TGN020	Aquaporin , PROTAC Linker
	TGN-020 is an inhibitor of Aquaporin 4 (AQP4, IC50: 3.1 μM), the most abundant water channel in the brain.		Aquaporin , PROTAC Linker
T7946	AER-271		Aquaporin
	AER-271 is an inhibitor of aquaporin-4.		Aquaporin
T21044	P-Tolylmaleimide	p Tolylmaleimide	Aquaporin
	p-Tolylmaleimide (p Tolylmaleimide) is an inhibitor of the water channel and binds to Aquaporin Z.		Aquaporin
T13381	Z433927330		Others
	Z433927330 is a potent and selective Aquaporin-7 (AQP7) inhibitor(IC50s of 0.2).		Others
T11014	DFP00173		Aquaporin
	DFP00173 is a potent and selective aquaporin 3 (AQP3) inhibitor. DFP00173 inhibits mouse and human AQP3 with IC50 of ~0.1-0.4 μM. Compared with the homologous AQP subtypes AQP7 and AQP9, DFP00173 is selective for AQP3.		Aquaporin
T24859	TC-AQP1-1		Aquaporin
	TC-AQP1-1 is a blocker of the aquaporin 1 channel identified by virtual screening and inhibits water flux through hAQP1 in Xenopus laevis oocyte swelling assays at low micromolar concentrations.		Aquaporin
T20887	Atorvastatin Sodium	Lipitor	LDL , Aquaporin , HMG-CoA Reductase
	Atorvastatin Sodium (Lipitor) is a competitive inhibitor of HMG-CoA reductase and increases the expression of low density lipoprotein (LDL) receptors on hepatocytes. Atorvastatin Sodium treatment inhibits aquaporin 4 to ...		LDL , Aquaporin , HMG-CoA Reductase
T71598	AqB011
	AqB011 is a selective blocker of the Aquaporin-1 ion channel conductance, slowing cancer cell migration.
T69387	NMO-IgG blocker A-01
	NMO-IgG blocker A-01 is a idiotype-specific blocker of neuromyelitis opticaimmunoglobulin g (nmo-igg) binding to aquaporin-4 (aqp4)
T71599	AqB007
	AqB007 is a selective blocker of the Aquaporin-1 ion channel conductance, thereby slowing cancer cell migration.
T24769	Scaff10-8	Scaff 10 8,Scaff-10-8
	Scaff10-8 is an inhibitor of AKAP-Lbc-RhoA interaction that acts by promoting the translocation of aquaporin-2 to the plasma membrane of renal collecting duct principal cells.
T74230	Dioleoylphosphatidylglycerol
	Dioleoylphosphatidylglycerol (DOPG), a naturally occurring phospholipid, is synthesized through the action of aquaporin 3 (AQP3) and phospholipase D2 (PLD2). It functions to suppress the production of inflammatory mediat...

Compounds

TGN-020

T5102

Synonym: TGN020

Target: Aquaporin, PROTAC Linker

Synonym: p Tolylmaleimide

Target: LDL, Aquaporin, HMG-CoA Reductase

Synonym: Scaff 10 8,Scaff-10-8

Target:

Dioleoylphosphatidylglycerol

T74230

Synonym:

Target:

Cat No.	Product Name	Targets
TN1420	Bacopaside I	Others
	Bacopaside I is a saponin isolated from Bacopa monniera. Bacopaside I is a modulator of Aquaporin-1 channel, has neuroprotective functions, it has anti-Alzheimer's disease, it ameliorates cognitive impairment in APP/PS1 ...	Others
TN1421	Bacopaside II	Apoptosis
	Bacopaside II is a potential anti-angiogenic agent, it can reduce endothelial cell migration and tubulogenesis and induce apoptosis.	Apoptosis

Natural Products

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPH-00954	Aquaporin-5/AQP5 Protein, Human, Recombinant (His)	Human	in vitro E. coli expression system
	Aquaporin-5/AQP5 Protein, Human, Recombinant (His) is expressed in in vitro E. coli expression system.
TMPH-02980	Aquaporin-4/AQP4 Protein, Mouse, Recombinant (His)	Mouse	Yeast
	Forms a water-specific channel. Plays an important role in brain water homeostasis and in glymphatic solute transport. Required for a normal rate of water exchange across the blood brain interface. Required for normal le...
TMPH-00952	Aquaporin-1/AQP1 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Aquaporin-1/AQP1 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli.
TMPH-00953	Aquaporin-4/AQP4 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Aquaporin-4/AQP4 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli.
TMPH-00580	Aquaporin Z Protein, E. coli, Recombinant (His)	E. coli	in vitro E. coli expression system
	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid...
TMPH-03246	AQP2 Protein, Rat, Recombinant (His)	Rat	in vitro E. coli expression system
	Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Plays an essential rol...
TMPH-02523	AQP2 Protein, Mouse, Recombinant (His)	Mouse	in vitro E. coli expression system
	Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Plays an essential rol...
TMPJ-00045	Podoplanin Protein, Human, Recombinant (hFc)	Human	Human Cells
	Podoplanin is a type-1 transmembrane protein that belongs to Podoplanin family. PDPN expressed in various specialized cell types throughout the body. It highly expressed in placenta, lung, skeletal muscle and brain, weak...
TMPJ-00055	Podoplanin Protein, Mouse, Recombinant (hFc)	Mouse	Human Cells
	Podoplanin belongs to the podoplanin family, also known as Glycoprotein 38. Podoplanin is synthesized as a 172 amino acid (aa) precursor with a 22 aa signal sequence, a 119 aa extracellular domain (ECD), a 21 aa transmem...