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Search Results for " piezo1 "

Targets

3

Compounds

1

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T7506 Yoda 1 Piezo Channel
Yoda1 is a Piezo1 ion channel agonist (EC50s = 17.1 and 26.6 μM for murine and human Piezo1-transfected HEK293T cells, respectively)
Fr13138 Jedi2
Jedi2 is a Piezo1 activator rather than a specific Piezo2 activator. Jedi2 binds to the mouse Piezo1 proteins with a K d of 2770 μM [1].
T11076 Dooku1 Others
Dooku1 is an analog of Yoda1 and a selective antagonist of endogenous Piezo1 channels. Dooku1 inhibits Ca2+ entry induced by 2μMYoda1 with IC50 values of 1.3μM (in HEK 293 cells) and 1.5μM (in HUVEC). Dooku1 inhibits Yod...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPH-01863 PIEZO1 Protein, Human, Recombinant (His & Myc) Human E. coli
Pore-forming subunit of a mechanosensitive non-specific cation channel. Generates currents characterized by a linear current-voltage relationship that are sensitive to ruthenium red and gadolinium. Plays a key role in ep...
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