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Cat No. | Product Name | Synonyms | Targets |
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T7506 | Yoda 1 | Piezo Channel | |
Yoda1 is a Piezo1 ion channel agonist (EC50s = 17.1 and 26.6 μM for murine and human Piezo1-transfected HEK293T cells, respectively) | |||
Fr13138 | Jedi2 | ||
Jedi2 is a Piezo1 activator rather than a specific Piezo2 activator. Jedi2 binds to the mouse Piezo1 proteins with a K d of 2770 μM [1]. | |||
T11076 | Dooku1 | Others | |
Dooku1 is an analog of Yoda1 and a selective antagonist of endogenous Piezo1 channels. Dooku1 inhibits Ca2+ entry induced by 2μMYoda1 with IC50 values of 1.3μM (in HEK 293 cells) and 1.5μM (in HUVEC). Dooku1 inhibits Yod... |
Cat No. | Product Name | Species | Expression System |
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TMPH-01863 | PIEZO1 Protein, Human, Recombinant (His & Myc) | Human | E. coli |
Pore-forming subunit of a mechanosensitive non-specific cation channel. Generates currents characterized by a linear current-voltage relationship that are sensitive to ruthenium red and gadolinium. Plays a key role in ep... |