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amg510

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(S)-AMG-510
T222582252403-56-6
(S)-AMG-510 is an S-type compound of AMG-510, a potent covalent inhibitor of KRAS G12C with potential antitumor activity.
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Sotorasib
T86842296729-00-3
Sotorasib (AMG-510) is an orally active and selective covalent inhibitor of KRAS G12C. Sotorasib binds to the GDP state of the inactive conformation of KRAS G12C and inhibits KRAS and its downstream signaling. Sotorasib exhibits inhibitory activity against KRAS G12C mutant tumors.
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