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  • 5-HT Receptor
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antimigraine activity

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  • Inhibitors & Agonists
    3
    TargetMol | Activity
Sumatriptan succinate
GR 43175
T0203103628-48-4
Sumatriptan succinate (GR 43175), a serotonin1 (5-HT1) receptor agonist, is used in the acute treatment of a migraine headache.
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Sumatriptan hydrochloride
T60989103628-62-2
Sumatriptan (GR 43175) hydrochloride can be used in the research of migraine headache that is an orally active agonist of 5-HT1 receptor. The Ki values of Sumatriptan hydrochloride against 5-HT1D, 5-HT1B and 5-HT1A receptors are 17 nM, 27 nM and 100 nM, respectively. [1] [2].
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1-2 weeks
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Sumatriptan
GR 43175 free base
T23405103628-46-2
Sumatriptan (GR 43175 free base) is an orally active and potent 5-hydroxytryptamine 1 (5-HT1) receptor agonist that crosses the blood-brain barrier and has anti-inflammatory activity with high affinity for 5-HT1D, 5-HT1B, and 5-HT1F receptors for use in acute migraines and acute myocardial infarction.
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7-10 days
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