biotin-peg4-amino-t-bu-dadps-c3-alykne

Biotin-PEG4-amino-t-Bu-DADPS-C3-alkyne serves as a PEG-based linker for PROTAC synthesis [1].

Biotin-PEG4-amino-t-Bu-DADPS-C6-azide is a PEGylated PROTAC linker suitable for PROTAC synthesis [1].

Biotin-C5-amino-C5-amino is an alkyl chain-based PROTAC linker utilized in PROTAC synthesis.

N-(Amino-PEG4)-N-Biotin-PEG4-acid is a PEG-based PROTAC linker incorporating biotin for labeling, making it a versatile tool in PROTAC synthesis[1].

Biotin-PEG-triethoxysilane (MW 1000) is a PEG-based PROTAC linker used in the synthesis of PROTACs[1].

Biotin-PEG3-(CH2)3-NH2 TFA salt is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

DBCO-(PEG)3-VC-PAB-MMAE is a chemical compound where monomethyl auristatin E (MMAE), a potent tubulin inhibitor used as a toxin payload in antibody-drug conjugates, is conjugated via a DBCO-(PEG)3-vc-PAB linker.

Amino-PEG7-t-butyl ester is a PEG-based linker for PROTACs that joins two essential ligands, facilitating selective protein degradation through the ubiquitin-proteasome system within cells.

Biotin-PEG-amine (MW 2000) is a polyethylene glycol (PEG) derivative commonly used as a linker in the synthesis of proteolysis targeting chimeras (PROTACs)[1].

DSPE-PEG-Biotin (MW 2000) is a PEG-based PROTAC linker for PROTAC synthesis.

Biotin-PEG-triethoxysilane (MW 5000) is a PEG-based PROTAC linker used in PROTAC synthesis[1].

(4-Oxo-4H-quinazolin-3-yl)-acetic acid is an alkyl chain-derived PROTAC linker applicable for the synthesis of PROTACs [1].

4-Boc-amino-22-dimethylbutyric acid is an alkyl ether-derived PROTAC linker, suitable for PROTAC synthesis.

4-(6-Methyl-1,2,4,5-tetrazin-3-yl)phenol is an alkyl chain-derived PROTAC linker used in the synthesis of PROTACs[1].

Biotin-PEG-triethoxysilane (MW 2000) is a polyethylene glycol (PEG) derivative functionalized with triethoxysilane and biotin moieties, serving as a PEG-based linker for PROTAC synthesis to facilitate the targeted degradation of proteins of interest.

4-(N-Boc-amino)-1,6-heptanedioic acid is an alkyl ether-based linker suitable for PROTAC synthesis [1].

DOTA-(t-butyl)3-PEG5-azide is a polyethylene glycol (PEG)-derived linker specifically designed for the synthesis of proteolysis targeting chimeras (PROTACs)[1].

1-(t-Boc-Aminooxy)-3-aminooxy-propane is an alkyl ether-based PROTAC linker used in the synthesis of PROTACs [1].

DP-C-4 is a Cereblon-based dual PROTAC for simultaneous degradation of EGFR and PARP[1]. DP-C-4 (1-50 μM; 24 hours) has degradation effects on EGFR and PARP simultaneously in a dose-dependent manner in SW1990 cells[1]. [1]. Mengzhu Zheng, et al. Rational Design and Synthesis of Novel Dual PROTACs for Simultaneous Degradation of EGFR and PARP. J Med Chem. 2021 May 26.

TAMRA-Azide-PEG-biotin is a PEG-based linker for PROTACs, joining two essential ligands. This linker facilitates selective protein degradation by utilizing the ubiquitin-proteasome system within cells.

Biotin-PEG-amine (MW 3400) is a polyethylene glycol (PEG)-based linker compound used in the synthesis of PROTACs [1].

N-Boc-PEG-t-butyl ester is a PEG-based linker for PROTACs, joining two essential ligands to facilitate selective protein degradation via the ubiquitin-proteasome system within cells.

Biotin-PEG-Biotin (MW 1000) is a PEG-derived PROTAC linker utilized in PROTAC synthesis [1].